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PubMed Publications| Keyword search (4,163 papers available) |  |
"Quality control" Keyword-tagged Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Metabolomics 2023 workshop report: moving toward consensus on best QA/QC practices in LC-MS-based untargeted metabolomics | Mosley JD; Dunn WB; Kuligowski J; Lewis MR; Monge ME; Ulmer Holland C; Vuckovic D; Zanetti KA; Schock TB; | 38980450 CHEMBIOCHEM |
| 2 | Establishing a framework for best practices for quality assurance and quality control in untargeted metabolomics | Mosley JD; Schock TB; Beecher CW; Dunn WB; Kuligowski J; Lewis MR; Theodoridis G; Ulmer Holland CZ; Vuckovic D; Wilson ID; Zanetti KA; | 38345679 CHEMBIOCHEM |
| 3 | Metabolomics 2022 workshop report: state of QA/QC best practices in LC-MS-based untargeted metabolomics, informed through mQACC community engagement initiatives | Dunn WB; Kuligowski J; Lewis M; Mosley JD; Schock T; Ulmer Holland C; Zanetti KA; Vuckovic D; | 37940740 CHEMBIOCHEM |
| 4 | An RNA granule for translation quality control in Saccharomyces cerevisiae | Dhaliwal JS; Panozzo C; Benard L; Zerges W; | 36373798 BIOLOGY |
| 5 | Dissemination and analysis of the quality assurance (QA) and quality control (QC) practices of LC-MS based untargeted metabolomics practitioners | Evans AM; O' Donovan C; Playdon M; Beecher C; Beger RD; Bowden JA; Broadhurst D; Clish CB; Dasari S; Dunn WB; Griffin JL; Hartung T; Hsu PC; Huan T; Jans J; Jones CM; Kachman M; Kleensang A; Lewis MR; Monge ME; Mosley JD; Taylor E; Tayyari F; Theodoridis G; Torta F; Ubhi BK; Vuckovic D; | 33044703 CONCORDIA |
| Title: | An RNA granule for translation quality control in Saccharomyces cerevisiae | ||||
| Authors: | Dhaliwal JS, Panozzo C, Benard L, Zerges W | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/36373798/ | ||||
| DOI: | 10.1242/jcs.260388 | ||||
| Publication: | Journal of cell science | ||||
| Keywords: | No-go decay; Oxidized RNA; RNA granules; Ribosome-associated quality control; Translation; | ||||
| PMID: | 36373798 | Category: | Date Added: | 2022-11-14 | |
| Dept Affiliation: |
BIOLOGY
1 Department of Biology, Concordia University, 7141 Sherbrooke W, Montreal, Quebec, H4B 1R6, Canada. 2 Institut de Biologie Physico-Chimique, UMR8226, CNRS, Sorbonne Université, 13, rue Pierre et Marie Curie, 75005, Paris, France. |
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Description: |
Cytoplasmic RNA granules compartmentalize phases of the translation cycle in eukaryotes. We previously reported the localization of oxidized RNA to cytoplasmic foci called oxidized RNA bodies (ORBs) in human cells. We show here that ORBs are RNA granules in Saccharomyces cerevisiae. Several lines of evidence support a role of ORBs in the compartmentalization of no-go decay and ribosome quality control, the translation quality control pathways that recognize and clear aberrant mRNAs, including those with oxidized bases. Translation is required by these pathways and ORBs. Translation quality control factors localize to ORBs. A substrate of translation quality control, a stalled mRNA-ribosome-nascent chain complex, localizes to ORBS. Translation quality control mutants have altered ORB numbers, sizes, or both. In addition, we identify 68 ORB proteins, by immunofluorescence staining directed by proteomics, which further support their role in translation quality control and reveal candidate new factors for these pathways. |
