PERFORM Publications

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Title		Authors	PubMed ID
1	A Fully Virtual Graded Exertion Test Is Safe and Feasible in Symptomatic and Asymptomatic Children With Concussion	Coupal J; Shabanova D; Gagnon I; Grilli L; Beaulieu C; Teel E;	41816309 SOH
2	Psychosocial Outcomes Reported in Randomized Behavioral Intervention Trials for Children and Adolescents with Overweight and Obesity: A Scoping Review	Sacco S; Booij L; Kwok C; Carrière K; Hall K; Baluyot TC; Forouhar V; Côté M; Pietrasik M; Jebeile H; Ball GDC; Johnston BC; Alberga AS;	41601261 HKAP
3	Preexisting Mental Health Disorders Are Associated With Acute Clinical Presentation and Longitudinal Recovery Trajectories in Adolescents With Concussion	Iuliano SG; Gagnon IJ; Iverson GL; Cook NE; Zemek R; Teel EF;	41505351 SOH
4	Comparing the impact of in-person vs. virtual 10-week family-based childhood obesity management program on anthropometric, cardiometabolic, and mental health outcomes	Heidl AJ; Sun D; Faustini C; Gierc M; Bains A; Cohen TR;	41332896 MATHSTATS
5	Prevalence and characteristics of neuropathic pain in adolescent survivors of childhood cancer	Mesaroli G; Olaizola S; Nair A; Nishat F; Pizzo A; Nathan PC; Alberts NM; Stinson JN;	40999274 PSYCHOLOGY
6	Deep learning-based feature discovery for decoding phenotypic plasticity in pediatric high-grade gliomas single-cell transcriptomics	Abicumaran Uthamacumaran	40848317 PSYCHOLOGY
7	Intolerance of uncertainty, psychological symptoms, and pain in long-term childhood cancer survivors: a report from the Childhood Cancer Survivor Study	Alberts NM; Stratton KL; Leisenring WM; Pizzo A; Lamoureux É; Alschuler K; Flynn J; Krull KR; Jibb LA; Nathan PC; Olgin JE; Stinson JN; Armstrong GT;	40699439 PSYCHOLOGY
8	Biopsychosocial risk factors for pain in early phases of pediatric cancer treatment	Klages KL; James RN; Kain ZN; Phipps S; Alberts NM; Fortier MA;	40365620 PSYCHOLOGY
9	Supporting parent capacity to manage pain in young children with cancer at home: Co-design and usability testing of the PainCaRe app	Jibb LA; Liu W; Stinson JN; Nathan PC; Chartrand J; Alberts NM; Hashemi E; Masama T; Pease HG; Torres LB; Cortes HG; Kuczynski S; Liu S; La H; Fortier MA;	39473834 CONCORDIA
10	Adiposity and cardiac autonomic function in children with a family history of obesity	Saade MB; Holden S; Kakinami L; McGrath JJ; Mathieu MÈ; Poirier P; Barnett TA; Beaucage P; Henderson M;	39304555 PERFORM
11	Comparison of parent-reported motivators of non-vaccination for children 5-11 years old in Australia and Canada: Results of the iCARE study	Deslauriers F; Hoq M; Kaufman J; Enticott J; Lavoie KL; Bacon SL; Boyle JA; Danchin M;	38880694 HKAP
12	Deserve's Got Nothin' to Do With It: A Philosopher Visits the NICU	David I Waddington	30214922 EDUCATION
13	Co-Development of Three Dietary Indices to Facilitate Dietary Intake Assessment of Pediatric Crohn's Disease Patients	Harvey A.; Mannette J.; Sigall-Boneh R.; Macintyre B.; Parrott M.; Cahill L.; Connors J.; Otley A.; Haskett J.; van Limbergen J.; Grant S.;	38634640 PERFORM
14	Striking a balance: triage and crisis intervention models within the pediatric emergency room	Laporte N; Hechtman L; Rousseau C; Greenfield B;	37920538 PSYCHOLOGY
15	Screening for parent and child ADHD in urban pediatric primary care: pilot implementation and stakeholder perspectives	Lui JHL; Danko CM; Triece T; Bennett IM; Marschall D; Lorenzo NE; Stein MA; Chronis-Tuscano A;	37442955 PSYCHOLOGY
16	Canadian pediatric eating disorder programs and virtual care during the COVID-19 pandemic: a mixed-methods approach to understanding clinicians' perspectives	Novack K; Dufour R; Picard L; Taddeo D; Nadeau PO; Katzman DK; Booij L; Chadi N;	37101241 PSYCHOLOGY
17	Chronic pain in children and adolescents diagnosed with cancer: the challenge of mitigating the pain and the potential of integrating exercise into pain management	Caru M; Alberts NM; Freeman MC; Dandekar SC; Rao P; McKeone DJ; Brown VI; McGregor LM; Schmitz KH;	36952029 PSYCHOLOGY
18	A multi-center, randomized, 12-month, parallel-group, feasibility study to assess the acceptability and preliminary impact of family navigation plus usual care versus usual care on attrition in managing pediatric obesity: a study protocol	Ball GDC; O' Neill MG; Noor R; Alberga A; Azar R; Buchholz A; Enright M; Geller J; Ho J; Holt NL; Lebel T; Rosychuk RJ; Tarride JE; Zenlea I;	36691103 HKAP
19	Electroencephalographic characteristics of children and adolescents with chronic musculoskeletal pain	Ocay DD; Teel EF; Luo OD; Savignac C; Mahdid Y; Blain-Moraes S; Ferland CE;	36601627 HKAP
20	Acceptability of Serious Games in Pediatric Asthma Education and Self-management: Pilot Study	Silva-Lavigne N; Valderrama A; Pelaez S; Bransi M; Balli F; Gervais Y; Gaudy T; Tse SM;	35389354 CONCORDIA
21	Validation of desk-based audits using Google Street View® to monitor the obesogenic potential of neighbourhoods in a pediatric sample: a pilot study in the QUALITY cohort	Roberge JB; Contreras G; Kakinami L; Van Hulst A; Henderson M; Barnett TA;	35346220 PERFORM
22	Family Members' Perceptions of Their Psychological Responses One Year Following Pediatric Intensive Care Unit (PICU) Hospitalization: Qualitative Findings From the Caring Intensively Study	Rennick JE; Knox AM; Treherne SC; Dryden-Palmer K; Stremler R; Chambers CT; McRae L; Ho M; Stack DM; Dougherty G; Fudge H; Campbell-Yeo M;	34557460 CONCORDIA
23	Validation of a Portable Game Controller to Assess Peak Expiratory Flow Against Conventional Spirometry in Children: Cross-sectional Study.	Chelabi K, Balli F, Bransi M, Gervais Y, Marthe C, Tse SM	33512326 CONCORDIA
24	Pain in long-term survivors of childhood cancer: A systematic review of the current state of knowledge and a call to action from the Children's Oncology Group.	Schulte FSM, Patton M, Alberts NM, Kunin-Batson A, Olson-Bullis BA, Forbes C, Russell KB, Neville A, Heathcote LC, Karlson CW, Racine NM, Charnock C, Hocking MC, Banerjee P, Tutelman PR, Noel M, Krull KR	33112416 PSYCHOLOGY
25	Body composition parameters can better predict body size dissatisfaction than body mass index in children and adolescents.	Dos Santos RRG, Forte GC, Mundstock E, Amaral MA, da Silveira CG, Amantéa FC, Variani JF, Booij L, Mattiello R	31338791 PSYCHOLOGY

Title:	Prevalence and characteristics of neuropathic pain in adolescent survivors of childhood cancer
Authors:	Mesaroli G, Olaizola S, Nair A, Nishat F, Pizzo A, Nathan PC, Alberts NM, Stinson JN
Link:	https://pubmed.ncbi.nlm.nih.gov/40999274/
DOI:	10.1007/s11764-025-01892-4
Publication:	Journal of cancer survivorship : research and practice
Keywords:	Cancer survivors; Neuropathic pain; Pain; Pediatric;
PMID:	40999274	Category:	Date Added:	2025-09-26
Dept Affiliation:	PSYCHOLOGY 1 Department of Physical Therapy, University of Toronto, Toronto, Canada. giulia.mesaroli@sickkids.ca. 2 Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada. giulia.mesaroli@sickkids.ca. 3 Department of Rehabilitation Services, The Hospital for Sick Children, Toronto, Canada. giulia.mesaroli@sickkids.ca. 4 Child Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, Canada. giulia.mesaroli@sickkids.ca. 5 Child Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, Canada. 6 Dalla Lana School Public Health, University of Toronto, Toronto, Canada. 7 Department of Psychology, Concordia University, Montreal, Canada. 8 Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, Canada. 9 Lawrence Bloomberg Faculty of Nursing, University of Toronto, Toronto, Canada.

Description:

Purpose: Neuropathic pain (NP) in individuals with cancer can arise from the cancer itself or its treatments. The prevalence of NP has been estimated in children living with cancer; however, the prevalence in adolescent survivorship is unknown. The aims of this study were to estimate the prevalence of NP among adolescent survivors of childhood cancer and explore biopsychosocial factors associated with NP.

Methods: This was a cross-sectional study of cancer survivors (diagnosed > 18 months prior) aged 13-18 years in a pediatric cancer survivorship clinic. A survey was administered to participants assessing demographic, pain and psychosocial characteristics; moreover, NP was measured using self-report screening tools (painDETECT and Pediatric PainSCAN©). Disease characteristics were extracted from participants' health records. Descriptive statistics were used to report prevalence rates, pain, cancer and treatment characteristics. Fisher's exact and Mann-Whitney U tests were used to examine between group characteristics.

Results: 142 participants completed the study (median age 15, 52% female, 51% White). Primary cancer diagnosis was acute lymphoblastic leukemia in 53% of participants. The prevalence of pain was 23% (33/142) and that of NP was estimated to be 11% (16/142). Participants with NP (n = 16) had higher pain catastrophizing scores than participants with non-NP (n = 17; p = 0.0020).

Conclusions: Pain, including NP, is common in adolescent survivors of childhood cancer. Further research is needed to better understand the experience of NP in this population, including its trajectory over time, to improve pain management.

Implications for cancer survivors: Health care providers should routinely screen for pain in adolescent cancer survivors to initiate appropriate treatments.

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