Keyword search (4,163 papers available)

"Particle image velocimetry" Keyword-tagged Publications:

Title Authors PubMed ID
1 Experimental Investigation of the Effect of a MitraClip on Left Ventricular Flow Dynamics Teimouri K; Darwish A; Saleh W; Ng HD; Kadem L; 40325266
ENCS
2 Design, manufacturing, and multi-modal imaging of stereolithography 3D printed flexible intracranial aneurysm phantoms Yalman A; Jafari A; Léger É; Mastroianni MA; Teimouri K; Savoji H; Collins DL; Kadem L; Xiao Y; 39546636
BIOLOGY
3 Impact of Mitral Regurgitation on the Flow in a Model of a Left Ventricle. Papolla C, Darwish A, Kadem L, Rieu R 33000444
ENCS
4 Experimental Investigation of Left Ventricular Flow Patterns After Percutaneous Edge-to-Edge Mitral Valve Repair. Jeyhani M, Shahriari S, Labrosse M 29168199
IMAGING

 

Title:Experimental Investigation of Left Ventricular Flow Patterns After Percutaneous Edge-to-Edge Mitral Valve Repair.
Authors:Jeyhani M,  Shahriari S,  Labrosse M
Link:https://www.ncbi.nlm.nih.gov/pubmed/29168199?dopt=Abstract
DOI:10.1111/aor.13020
Publication:Artificial organs
Keywords:Doppler echocardiography;  Flow pattern;  Hemodynamic performance;  Mitral valve;  Particle image velocimetry;  Percutaneous edge-to-edge repair; 
PMID:29168199 Category:Artif Organs Date Added:2019-06-20
Dept Affiliation: IMAGING
1 Department of Mechanical and Industrial Engineering, Ryerson University, Toronto, Ontario, Canada.
2 Department of Mechanical and Industrial Engineering, Concordia University, Montreal, Quebec, Canada.
3 Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, Ontario, Canada.
4 Department of Mechanical Engineering, University of Ottawa, Ottawa, Ontario, Canada.

Description:

Experimental Investigation of Left Ventricular Flow Patterns After Percutaneous Edge-to-Edge Mitral Valve Repair.

Artif Organs. 2018 May;42(5):516-524

Authors: Jeyhani M, Shahriari S, Labrosse M

Abstract

Mitral valve percutaneous edge-to-edge repair (PEtER) is a viable solution in high-risk patients with severe symptomatic mitral regurgitation. However, the generated double-orifice configuration poses challenges for the evaluation of the hemodynamic performance of the mitral valve and may alter flow patterns in the left ventricle (LV) during diastole. This in vitro study aims to evaluate the hemodynamic modifications following a simulated PEtER. A custom-made mitral valve was developed, and two configurations were tested: (i) a single-orifice valve with mitral regurgitation and (ii) a double-orifice mitral valve configuration following PEtER. The hemodynamic performance of the valve was evaluated using Doppler echocardiography and catheterization, while the flow patterns in the LV were investigated using particle image velocimetry (PIV). The tests were run at a stroke volume of 65 mL and a heart rate of 70 bpm. PEtER was found to significantly reduce the regurgitant volume (15 vs. 34 mL). There was a good agreement between Doppler and catheter transmitral pressure gradients (peak gradient: 9 vs. 7 mm Hg; mean gradient: 4 vs. 3 mm Hg) as well as an excellent agreement between maximal velocity measured by Doppler and PIV (1.60 vs. 1.58 m/s). Vortex development in the LV during diastole was significantly different after repair. PEtER significantly increased the amplitude of Reynolds and viscous shear stresses, as well as the number of high shear regions in the LV, potentially promoting thromboembolism events.

PMID: 29168199 [PubMed - indexed for MEDLINE]




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