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PubMed Publications| Keyword search (4,163 papers available) |  |
Concordia Publications:
| Title: | On-chip integration of droplet microfluidics and nanostructure-initiator mass spectrometry for enzyme screening | ||||
| Authors: | Joshua Heinemann | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/27957569/ | ||||
| DOI: | 10.1039/c6lc01182a | ||||
| Publication: | Lab on a chip | ||||
| Keywords: | |||||
| PMID: | 27957569 | Category: | Lab Chip | Date Added: | 2019-06-20 |
| Dept Affiliation: |
MASSSPEC
1 Joint Bioenergy Institute, Emeryville, California 94608, USA and Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA. trnorthen@lbl.gov. 2 Joint Bioenergy Institute, Emeryville, California 94608, USA and Sandia National Laboratories, Livermore, California 94551, USA. 3 Department of Electrical and Computer Engineering, Concordia University, Montreal, Quebec, Canada. 4 Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA. trnorthen@lbl.gov. 5 Joint Bioenergy Institute, Emeryville, California 94608, USA and Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA. trnorthen@lbl.gov and Department of Bioengineering, University of California, Berkeley, California, 94720, USA. 6 Joint Bioenergy Institute, Emeryville, California 94608, USA and Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA. trnorthen@lbl.gov and Joint Genome Institute, Walnut creek, California, 94598, USA. |
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Description: |
Biological assays often require expensive reagents and tedious manipulations. These shortcomings can be overcome using digitally operated microfluidic devices that require reduced sample volumes to automate assays. One particular challenge is integrating bioassays with mass spectrometry based analysis. Towards this goal we have developed µNIMS, a highly sensitive and high throughput technique that integrates droplet microfluidics with nanostructure-initiator mass spectrometry (NIMS). Enzyme... |
