Keyword search (4,163 papers available)

"Psychoneuroendocrinology" Category Publications:

Title Authors PubMed ID
1 Appetitive olfactory conditioning in the neonatal male rat facilitates subsequent sexual partner preference. Ménard S, Gelez H, Jacubovitch M, Coria-Avila GA, Pfaus JG 32919208
PSYCHOLOGY
2 Stress-Related Trajectories of Diurnal Cortisol in Older Adulthood Over 12 Years. Herriot H, Wrosch C, Hamm JM, Pruessner JC 32866774
CONCORDIA
3 Disaster-related prenatal maternal stress predicts HPA reactivity and psychopathology in adolescent offspring: Project Ice Storm. Yong Ping E, Laplante DP, Elgbeili G, Jones SL, Brunet A, King S 32442863
PSYCHOLOGY
4 The non-aromatizable androgen dihydrotestosterone (DHT) facilitates sexual behavior in ovariectomized female rats primed with estradiol. Maseroli E, Santangelo A, Lara-Fontes B, Quintana GR, Mac Cionnaith CE, Casarrubea M, Ricca V, Maggi M, Vignozzi L, Pfaus JG 32087523
PSYCHOLOGY
5 Interpersonal capitalization moderates the associations of chronic caregiving stress and depression with inflammation. Gouin JP, Wrosch C, McGrath J, Booij L 31744782
PSYCHOLOGY
6 Modulation of spatial and response strategies by phase of the menstrual cycle in women tested in a virtual navigation task. Hussain D, Hanafi S, Konishi K, Brake WG, Bohbot VD 27213559
PSYCHOLOGY
7 Peripheral DNA methylation of HPA axis-related genes in humans: Cross-tissue convergence, two-year stability and behavioural and neural correlates. Di Sante J, Ismaylova E, Nemoda Z, Gouin JP, Yu WJ, Caldwell W, Vitaro F, Szyf M, Tremblay RE, Booij L 30059826
PSYCHOLOGY
8 Dehydroepiandrosterone impacts working memory by shaping cortico-hippocampal structural covariance during development. Nguyen TV, Wu M, Lew J, Albaugh MD, Botteron KN, Hudziak JJ, Fonov VS, Collins DL, Campbell BC, Booij L, Herba C, Monnier P, Ducharme S, McCracken JT 28946055
PSYCHOLOGY
9 Automatic and effortful emotional information processing regulates different aspects of the stress response. Ellenbogen MA, Schwartzman AE, Stewart J, Walker CD 16289608
PSYCHOLOGY
10 Daytime cortisol and stress reactivity in the offspring of parents with bipolar disorder. Ellenbogen MA, Hodgins S, Walker CD, Couture S, Adam S 17055665
CRDH
11 Structure provided by parents in middle childhood predicts cortisol reactivity in adolescence among the offspring of parents with bipolar disorder and controls. Ellenbogen MA, Hodgins S 19193493
CRDH
12 Intranasal oxytocin attenuates the cortisol response to physical stress: a dose-response study. Cardoso C, Ellenbogen MA, Orlando MA, Bacon SL, Joober R 22889586
PSYCHOLOGY
13 Intranasal oxytocin impedes the ability to ignore task-irrelevant facial expressions of sadness in students with depressive symptoms. Ellenbogen MA, Linnen AM, Cardoso C, Joober R 22902063
PSYCHOLOGY
14 Salivary cortisol and interpersonal functioning: an event-contingent recording study in the offspring of parents with bipolar disorder. Ellenbogen MA, Linnen AM, Santo JB, aan het Rot M, Hodgins S, Young SN 23131593
PSYCHOLOGY
15 Stress-induced negative mood moderates the relation between oxytocin administration and trust: evidence for the tend-and-befriend response to stress? Cardoso C, Ellenbogen MA, Serravalle L, Linnen AM 23768973
PSYCHOLOGY
16 Oxytocin and psychotherapy: keeping context and person in mind. Cardoso C, Ellenbogen MA 24035601
PSYCHOLOGY
17 Tend-and-befriend is a beacon for change in stress research: a reply to Tops. Cardoso C, Ellenbogen MA 24755423
PSYCHOLOGY
18 The impact of attentional training on the salivary cortisol and alpha amylase response to psychosocial stress: importance of attentional control. Pilgrim K, Ellenbogen MA, Paquin K 24767623
PSYCHOLOGY
19 A meta-analytic review of the impact of intranasal oxytocin administration on cortisol concentrations during laboratory tasks: moderation by method and mental health. Cardoso C, Kingdon D, Ellenbogen MA 25086828
PSYCHOLOGY
20 Memory response to oxytocin predicts relationship dissolution over 18 months. Cardoso C, Kalogeropoulos C, Brown CA, Orlando MA, Ellenbogen MA 26986091
PSYCHOLOGY
21 Oxytocin and social context moderate social support seeking in women during negative memory recall. Cardoso C, Valkanas H, Serravalle L, Ellenbogen MA 27164224
PSYCHOLOGY
22 Successful aging, cognitive function, socioeconomic status, and leukocyte telomere length. Huang Y, Yim OS, Lai PS, Yu R, Chew SH, Gwee X, Nyunt MSZ, Gao Q, Ng TP, Ebstein RP, Gouin JP 30708136
PSYCHOLOGY
23 Facilitation of sexual behavior in ovariectomized rats by estradiol and testosterone: A preclinical model of androgen effects on female sexual desire. Jones SL, Ismail N, Pfaus JG 28278441
PSYCHOLOGY

 

Title:Peripheral DNA methylation of HPA axis-related genes in humans: Cross-tissue convergence, two-year stability and behavioural and neural correlates.
Authors:Di Sante J,  Ismaylova E,  Nemoda Z,  Gouin JP,  Yu WJ,  Caldwell W,  Vitaro F,  Szyf M,  Tremblay RE,  Booij L
Link:https://www.ncbi.nlm.nih.gov/pubmed/30059826?dopt=Abstract
DOI:10.1016/j.psyneuen.2018.07.019
Publication:Psychoneuroendocrinology
Keywords:Brain imaging;  DNA methylation;  FKBP5;  HPA-axis;  NR3C1;  Stress; 
PMID:30059826 Category:Psychoneuroendocrinology Date Added:2019-06-20
Dept Affiliation: PSYCHOLOGY
1 CHU Sainte-Justine Research Centre, Montreal, Canada; Department of Psychiatry, University of Montreal, Montreal, Canada; Department of Psychology, Concordia University, Montreal, Canada.
2 Department of Pharmacology and Therapeutics, McGill University, Montreal, Canada; Department of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary.
3 Department of Psychology, Concordia University, Montreal, Canada.
4 CHU Sainte-Justine Research Centre, Montreal, Canada; Department of Pharmacology and Therapeutics, McGill University, Montreal, Canada.
5 CHU Sainte-Justine Research Centre, Montreal, Canada; School of Psychoeducation, University of Montreal, Montreal, Canada.
6 Department of Pharmacology and Therapeutics, McGill University, Montreal, Canada.
7 CHU Sainte-Justine Research Centre, Montreal, Canada; Department of Psychology and Pediatrics, University of Montreal, Montreal, Canada; School of Public Health, Physiotherapy and Sports Science, University College Dublin, Ireland.
8 CHU Sainte-Justine Research Centre, Montreal, Canada; Department of Psychiatry, University of Montreal, Montreal, Canada; Department of Psychology, Concordia University, Montreal, Canada. Electronic address: linda.booij@concordia.ca.

Description:

Peripheral DNA methylation of HPA axis-related genes in humans: Cross-tissue convergence, two-year stability and behavioural and neural correlates.

Psychoneuroendocrinology. 2018 11;97:196-205

Authors: Di Sante J, Ismaylova E, Nemoda Z, Gouin JP, Yu WJ, Caldwell W, Vitaro F, Szyf M, Tremblay RE, Booij L

Abstract

Environmental factors can influence gene expression via epigenetic modifications such as DNA methylation. DNA methylation levels of regulatory regions in Hypothalamo-Pituitary-Adrenal (HPA) axis-related genes assessed from brain tissues as well as from surrogate, peripheral tissues have been associated with vulnerability to stress-related psychopathologies. Commonly used peripheral samples to assess DNA methylation in living humans are derived from blood, saliva or buccal cells. Although psychiatric epigenetic studies are increasingly relying on peripheral measures of DNA methylation, it is still unknown to what extent methylation patterns across peripheral tissues are associated with each other and with measures of brain processes and behavioural stress. In the present study, with a sample of 51 healthy adults, we assessed cross-tissue correlations of DNA methylation patterns in the glucocorticoid receptor (NR3C1) 1?F promoter and the FK506 Binding Protein 5 (FKBP5) gene intron 7 region using saliva and buccal cell samples, and assessed two-year stability in both tissues in a male subsample (N?=?14). We also investigated associations between peripherally-derived DNA methylation and measures of neural function and perceived daily stress, and compared the extent of these associations across tissue samples. DNA methylation cross-tissue correlations were highly significant for FKBP5, but not significant for NR3C1. DNA methylation in both genes remained stable for two years. Tissue- and gene-specific associations were found for brain resting state connectivity and neural responses to sadness, thereby suggesting that saliva- and buccal cell-derived DNA methylation levels of NR3C1-1?F and FKBP5 gene regions might differently capture different measures of putatively related brain processes. It was also found that greater buccal cell- (but not saliva-) derived NR3C1-1?F methylation was associated with lower perceived daily life demands. Results of the present study may inform the design of future epigenetic studies on FKBP5-intron-7 and NR3C1-1?F-promoter methylation in relation to neuro-imaging and behavioural measures, and provide insight for the development of peripheral DNA methylation correlates of stress sensitivity and resilience.

PMID: 30059826 [PubMed - indexed for MEDLINE]




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