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PubMed Publications| Keyword search (4,163 papers available) |  |
"J Anal Toxicol" Category Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Enzymatic assay for GHB determination in forensic matrices. | Grenier V, Huppé G, Lamarche M, Mireault P | 22722059 MASSSPEC |
| 2 | Procedure for the Selection and Validation of a Calibration Model I-Description and Application | Brigitte Desharnais | 28137730 CHEMBIOCHEM |
| 3 | Procedure for the Selection and Validation of a Calibration Model II-Theoretical Basis | Brigitte Desharnais | 28158619 CHEMBIOCHEM |
| 4 | Challenges Related to Three Cases of Fatal Intoxication to Multiple Novel Synthetic Opioids. | Garneau B, Desharnais B, Beauchamp-Doré A, Lavallée C, Mireault P, Lajeunesse A | 30927001 CHEMBIOCHEM |
| 5 | A Tool for Automatic Correction of Endogenous Concentrations: Application to BHB Analysis by LC-MS-MS and GC-MS | Desharnais B; Lajoie MJ; Laquerre J; Savard S; Mireault P; Skinner CD; | 31141151 CHEMBIOCHEM |
| Title: | Procedure for the Selection and Validation of a Calibration Model I-Description and Application | ||||
| Authors: | Brigitte Desharnais | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/28137730/ | ||||
| Publication: | Journal of analytical toxicology | ||||
| Keywords: | |||||
| PMID: | 28137730 | Category: | J Anal Toxicol | Date Added: | 2019-05-31 |
| Dept Affiliation: |
CHEMBIOCHEM
1 Department of Toxicology, Laboratoire de sciences judiciaires et de médecine légale, 1701 rue Parthenais, Montréal, Québec, Canada H2K 3S7. 2 Department of Chemistry & Biochemistry, Concordia University, 7141 Sherbrooke Street West, Montréal, Québec, Canada H4B 1R6. 3 Department of Mathematics, Université de Sherbrooke, 2500 boulevard de l'Université, Sherbrooke, Québec, CanadaJ1K 2R1. 4 Department of Toxicology, Laboratoire de sciences judiciaires et de médecine légale, 1701 rue Parthenais, Montréal, Québec, CanadaH2K 3S7. 5 Department of Chemistry & Biochemistry,Concordia University, 7141 Sherbrooke Street West, Montréal, Québec, CanadaH4B 1R6. |
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Description: |
Calibration model selection is required for all quantitative methods in toxicology and more broadly in bioanalysis. This typically involves selecting the equation order (quadratic or linear) and weighting factor correctly modelizing the data. A mis-selection of the calibration model will generate lower quality control (QC) accuracy, with an error up to 154%. Unfortunately, simple tools to perform this selection and tests to validate the resulting model are lacking. We present a stepwise,... |
