Keyword search (4,164 papers available)

"Weiler HA" Authored Publications:

Title Authors PubMed ID
1 Evaluation of Increasing Dairy Intake on Bone Density in Postpubertal Youth: A Randomized Controlled Trial Using Motivational Interviewing Slim M; Vanstone CA; Morin SN; Rahme E; Bacon SL; Weiler HA; 36967160
HKAP
2 Evaluation of Increasing Dairy Intake on Bone Density in Post-pubertal Youth: A Randomized Controlled Trial Using Motivational Interviewing Slim M; Vanstone CA; Morin SN; Rahme E; Bacon SL; Weiler HA; 35015862
HKAP
3 Arachidonic acid status negatively associates with forearm bone outcomes and glucose homeostasis in children with an overweight condition or obesity. Mak IL; Cohen TR; Vanstone CA; Weiler HA; 31269410
PERFORM
4 Conjugated linoleic acid mitigates testosterone-related changes in body composition in male guinea pigs. Yang SQ, DeGuire JR, Lavery P, Mak IL, Weiler HA, Santosa S 27101759
PERFORM
5 Regional adiposity and markers of inflammation in pre-school age children. Delaney KZ, Vanstone CA, Weiler HA, Santosa S 30315178
PERFORM

 

Title:Conjugated linoleic acid mitigates testosterone-related changes in body composition in male guinea pigs.
Authors:Yang SQ,  DeGuire JR,  Lavery P,  Mak IL,  Weiler HA,  Santosa S
Link:https://www.ncbi.nlm.nih.gov/pubmed/27101759?dopt=Abstract
DOI:10.1016/j.nutres.2015.12.013
Publication:Nutrition research (New York, N.Y.)
Keywords:Body fat;  Conjugated linoleic acid;  Guinea pig;  Hypogonadal;  Interleukin-6;  Testosterone; 
PMID:27101759 Category:Nutr Res Date Added:2019-04-15
Dept Affiliation: PERFORM
1 School of Dietetics and Human Nutrition, McGill University, Montreal, QC H9X 3V9, Canada.
2 Department of Exercise Science, Concordia University, Montreal, QC H4B 1R6, Canada; Nutrition, Obesity and Metabolism Lab, PERFORM Centre, Concordia University, Montreal, QC H4B 1R6, Canada. Electronic address: s.santosa@concordia.ca.

Description:

Conjugated linoleic acid mitigates testosterone-related changes in body composition in male guinea pigs.

Nutr Res. 2016 May;36(5):408-17

Authors: Yang SQ, DeGuire JR, Lavery P, Mak IL, Weiler HA, Santosa S

Abstract

We hypothesize that conjugated linoleic acid (CLA) may be effective in preventing the changes in total and regional body composition and increases in interleukin (IL) 6 that occur as a result of hypogonadism. Male guinea pigs (n = 40, 70- to 72-week retired breeders) were block randomized by weight into 4 groups: (1) sham surgery (SHAM)/control (CTRL) diet, (2) SHAM/conjugated linoleic acid (CLA) diet (1%), (3) orchidectomy (ORX)/CTRL diet, and (4) ORX/CLA diet. Dual-energy x-ray absorptiometry scans were performed at baseline and week 16 to assess body composition. Serum IL-6 was analyzed using an enzyme-linked immune sorbent assay. Fatty acids (FAs) from visceral and subcutaneous adipose tissue were analyzed using gas chromatography. In ORX/CTRL guinea pigs, percent total body fat increased by 6.1%, and percent lean mass decreased by 6.7% over the 16-week treatment period, whereas no changes were observed for either parameter in ORX/CLA guinea pigs. Guinea pigs fed the CLA diet gained less percent total, upper, and lower body fat than those fed the CTRL diet regardless of surgical treatment. Regional adipose tissue FA composition was reflective of dietary FAs. Serum IL-6 concentrations were not different among groups. In this study, we observed that, in male guinea pigs, hypogonadism resulted in increased fat mass and decreased lean mass. In addition, CLA was effective in reducing gains in body fat and maintaining lean mass in both hypogonadal and intact guinea pigs.

PMID: 27101759 [PubMed - indexed for MEDLINE]




BookR developed by Sriram Narayanan
for the Concordia University School of Health
Copyright © 2011-2026
Cookie settings
Concordia University