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PubMed Publications| Keyword search (4,164 papers available) |  |
"Stoletniy AS" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Association between categorization of emotionally-charged and neutral visual scenes and parameters of event-related potentials in carriers of different COMT, HTR2A, BDNF gene genotypes | Vorobyeva EV; Ermakov PN; Borokhovski EF; Kovsh EM; Stoletniy AS; | 32983417 PSYCHOLOGY |
| Title: | Association between categorization of emotionally-charged and neutral visual scenes and parameters of event-related potentials in carriers of different COMT, HTR2A, BDNF gene genotypes | ||||
| Authors: | Vorobyeva EV, Ermakov PN, Borokhovski EF, Kovsh EM, Stoletniy AS | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/32983417/ | ||||
| DOI: | 10.12688/f1000research.22503.2 | ||||
| Publication: | F1000Research | ||||
| Keywords: | BDNF genes polymorphisms; COMT; Categorization of emotionally-charged and neutral visual scenes; HTR2A; parameters of event-related potentials; | ||||
| PMID: | 32983417 | Category: | F1000Res | Date Added: | 2020-09-29 |
| Dept Affiliation: |
PSYCHOLOGY
1 Department of Psychophysiology and Clinical Psychology, Academy of Psychology and Education Sciences of Southern Federal University, Rostov-on-Don, 344006, Russian Federation. 2 Department of Education, Centre for the Study of Learning and Performance of Concordia University, Montreal, H3H 2S2, Canada. |
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Description: |
ackground: This study aimed to discover the association between parameters of event-related potentials (ERPs) and categorization of images of visual scenes, both emotionally-charged and neutral, in carriers of different genotypes of the COMT, HTR2A, BDNF genes. Methods: Electroencephalogram (EEG) and ERPs were recorded at 128 leads, with two ear referents. Images of different visual scenes were presented to the study participants sequentially on a monitor screen. The participants' task was to examine these images and indicate what emotions (negative, neutral or positive) they elicit. Comparison of event-related potentials was carried out using unpaired Student t-test in EEGLAB toolbox. Results: COMT. A stronger reaction, as reflected in the amplitude of the ERPs, in participants with the recessive homozygous Met/Met genotype was observed on latency around 200 ms to the stimuli, assessed as positive. Carriers of dominant homozygous Val/Val genotype had higher amplitude of 200 ms peak when assessed scene images as either neutral or negative in comparison to other genotypes. Participant with the Val/Met heterozygous genotype had higher amplitude of ERP that Met/Met group on same latency when assessed stimuli as negative. HTR2A . Significant increase in negativity in the parietal-occipital regions revealed in the range of 350-420 ms in participants with the recessive homozygous A/A genotype when choosing any type of assessment, compared to carriers of the heterozygous genotype A/G and the dominant homozygous G/G genotype. BDNF. Participants with Val/Val genotype categorized the visual images more thoroughly, as reflected in greater activation of the parietal-occipital zones and higher amplitude on ERP peak on 190 ms (negative assessment) and 160 ms (neutral assessment) then Val/Met carriers. Conclusions: The COMT, HTR2A, BDNF gene different genotypes are associated with the process of categorizing emotionally charged and neutral visual scenes, and this relationship is reflected in the ERP parameters. |
