Keyword search (4,164 papers available)

"Schoenbaum G" Authored Publications:

Title Authors PubMed ID
1 Disentangling prediction error and value in a formal test of dopamine s role in reinforcement learning Usypchuk AA; Maes EJP; Lozzi M; Avramidis DK; Schoenbaum G; Esber GR; Gardner MPH; Iordanova MD; 40738112
CSBN
2 Hippocampal output suppresses orbitofrontal cortex schema cell formation Zong W; Zhou J; Gardner MPH; Zhang Z; Costa KM; Schoenbaum G; 40229506
CONCORDIA
3 The Rescorla-Wagner Model: It Is Not What You Think It Is Esber G; Schoenbaum G; Iordanova MD; 39805526
CSBN
4 OFC neurons do not represent the negative value of a conditioned inhibitor Esber GR; Usypchuk A; Saini S; Deroche M; Iordanova MD; Schoenbaum G; 38042330
CONCORDIA
5 Calcium activity is a degraded estimate of spikes Hart EE; Gardner MPH; Panayi MC; Kahnt T; Schoenbaum G; 36368324
PSYCHOLOGY
6 Anterior cingulate neurons signal neutral cue pairings during sensory preconditioning Hart EE; Gardner MPH; Schoenbaum G; 34936884
PSYCHOLOGY
7 Causal evidence supporting the proposal that dopamine transients function as temporal difference prediction errors. Maes EJP, Sharpe MJ, Usypchuk AA, Lozzi M, Chang CY, Gardner MPH, Schoenbaum G, Iordanova MD 31959935
CSBN
8 Neural correlates of two different types of extinction learning in the amygdala central nucleus. Iordanova MD, Deroche ML, Esber GR, Schoenbaum G 27531638
CSBN

 

Title:Neural correlates of two different types of extinction learning in the amygdala central nucleus.
Authors:Iordanova MDDeroche MLEsber GRSchoenbaum G
Link:https://www.ncbi.nlm.nih.gov/pubmed/27531638?dopt=Abstract
DOI:10.1038/ncomms12330
Publication:Nature communications
Keywords:
PMID:27531638 Category:Nat Commun Date Added:2019-06-20
Dept Affiliation: CSBN
1 National Institute on Drug Abuse Intramural Research Program, Cellular Neurobiology Research Branch, Behavioral Neurophysiology Research Section, 251 Bayview Boulevard, Baltimore, Maryland 21224, USA.
2 Department of Anatomy and Neurobiology, University of Maryland, School of Medicine, 20 Penn Street, Baltimore, Maryland 21201, USA.
3 Department of Psychology and Centre for Studies in Behavioral Neurobiology, Concordia University, 7141 Sherbrooke West, Montreal, Quebec, Canada H4B 1R6.
4 Center for Research on Brain, Language, and Music, McGill University, 3640 Rue de la Montagne, Montreal, Quebec, Canada H3G 2A8.
5 Solomon H. Snyder Department of Neuroscience, the Johns Hopkins Univeristy, Baltimore, Maryland 21287, USA.

Description:

Neural correlates of two different types of extinction learning in the amygdala central nucleus.

Nat Commun. 2016 08 17;7:12330

Authors: Iordanova MD, Deroche ML, Esber GR, Schoenbaum G

Abstract

Extinction is a fundamental form of memory updating in which one learns to stop expecting an event that no longer occurs. This learning ensues when one experiences a change in environmental contingencies, that is, when an expected outcome fails to occur (simple extinction), or when a novel inflated expectation of a double outcome (overexpectation) is in conflict with the real outcome, and is a process that has been linked to amygdala function. Here, we show that in rats, the same neuronal population in the amygdala central nucleus updates reward expectancies and behaviour in both types of extinction, and neural changes in one paradigm are reflected in the other. This work may have implications for the management of addiction and anxiety disorders that require treatments based on the outcome omission, and disorders such as obesity that could use overexpectation, but not omission strategies.

PMID: 27531638 [PubMed - indexed for MEDLINE]





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