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PubMed Publications| Keyword search (4,163 papers available) |  |
"Phillips N" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Biological sex and bilingualism: Its impact on risk and resilience for dementia | Calvo N; Phillips N; Bialystok E; Einstein G; | 41573422 PSYCHOLOGY |
| 2 | Hearing loss is associated with decreased default-mode network connectivity in individuals with mild cognitive impairment | Grant N; Phillips N; | 40567819 PSYCHOLOGY |
| 3 | Connected speech profiles in mild cognitive impairment reflect global cognition | Pellerin S; Houzé B; Bedetti C; Phillips N; Brambati SM; | 40232260 PSYCHOLOGY |
| 4 | Biomarkers | Grant N; Phillips N; | 39785420 CONCORDIA |
| 5 | Clinical Manifestations | Phillips N; Best PT; Grant N; Kabir A; | 39750307 CONCORDIA |
| 6 | Clinical Manifestations | Calvo N; Siddiqui R; Phillips N; Einstein G; | 39750698 CONCORDIA |
| 7 | Basic Science and Pathogenesis | Lima BS; Rosa-Neto P; Phillips N; Borrie M; Roncero CT; Lahiri D; Dori D; Chertkow H; | 39751468 CONCORDIA |
| 8 | Impact of a national dementia research consortium: The Canadian Consortium on Neurodegeneration in Aging (CCNA) | Chertkow H; Phillips N; Rockwood K; Anderson N; Andrew MK; Bartha R; Beaudoin C; Bélanger N; Bellec P; Belleville S; Bergman H; Best S; Bethell J; Bherer L; Black S; Borrie M; Camicioli R; Carrier J; Cashman N; Chan S; Crowshoe L; Cuello C; Cynader M; Dang-Vu T; Das S; Dixon RA; Ducharme S; Einstein G; Evans AC; Fahnestock M; Feldman H; Ferland G; Finger E; Fisk JD; Fogarty J; Fon E; Gan-Or Z; Gauthier S; Greenwood C; Henri-Bellemare C; Herrmann N; Hogan DB; Hsiung R; Itzhak I; Jacklin K; Lanctôt K; Lim A; MacKenzie I; Masellis M; Maxwell C; McAiney C; McGilton K; McLaurin J; Mihailidis A; Mohades Z; Montero-Odasso M; Morgan D; Naglie G; Nygaard H; O' Connell M; Petersen R; Pilon R; Rajah MN; Rapoport M; Roach P; Robillard JM; Rogaeva E; Rosa-Neto P; Rylett J; Sadavoy J; St George-Hyslop P; Seitz D; Smith E; Stefanovic B; Vedel I; Walker JD; Wellington C; Whitehead V; Wittich W; | 39636028 HKAP |
| 9 | Development and validation of risk of CPS decline (RCD): a new prediction tool for worsening cognitive performance among home care clients in Canada | Guthrie DM; Williams N; O' Rourke HM; Orange JB; Phillips N; Pichora-Fuller MK; Savundranayagam MY; Sutradhar R; | 38041046 CRDH |
| 10 | Associations Between Cardiovascular Risk Factors and Audiometric Hearing: Findings From the Canadian Longitudinal Study on Aging | Mick PT; Kabir R; Pichora-Fuller MK; Jones C; Moxham L; Phillips N; Urry E; Wittich W; | 37122082 PSYCHOLOGY |
| 11 | The association between information and communication technologies, loneliness and social connectedness: A scoping review | Petersen B; Khalili-Mahani N; Murphy C; Sawchuk K; Phillips N; Li KZH; Hebblethwaite S; | 37034933 PSYCHOLOGY |
| 12 | Consensus Statement Regarding the Application of Biogen to Health Canada for Approval of Aducanumab | Chertkow H; Rockwood K; Hogan DB; Phillips N; Montero-Odasso M; Amanullah S; Black S; Bocti C; Borrie M; Feldman H; Freedman M; Hsiung R; Kirk A; Masellis M; Nygaard H; Rajji T; Verret L; | 34912492 PSYCHOLOGY |
| 13 | Neural correlates of resilience to the effects of hippocampal atrophy on memory. | Belleville S, Mellah S, Cloutier S, Dang-Vu TT, Duchesne S, Maltezos S, Phillips N, Hudon C, CIMA-Q group | 33360019 HKAP |
| 14 | CCCDTD5 recommendations on early non cognitive markers of dementia: A Canadian consensus | Montero-Odasso M; Pieruccini-Faria F; Ismail Z; Li K; Lim A; Phillips N; Kamkar N; Sarquis-Adamson Y; Speechley M; Theou O; Verghese J; Wallace L; Camicioli R; | 33094146 CRDH |
| 15 | The Prevalence of Hearing, Vision, and Dual Sensory Loss in Older Canadians: An Analysis of Data from the Canadian Longitudinal Study on Aging. | Mick PT, Hämäläinen A, Kolisang L, Pichora-Fuller MK, Phillips N, Guthrie D, Wittich W | 32546290 PSYCHOLOGY |
| 16 | Sensory-cognitive associations are only weakly mediated or moderated by social factors in the Canadian Longitudinal Study on Aging. | Hämäläinen A, Phillips N, Wittich W, Pichora-Fuller MK, Mick P | 31873079 PSYCHOLOGY |
| 17 | Evidence of a Relation Between Hippocampal Volume, White Matter Hyperintensities, and Cognition in Subjective Cognitive Decline and Mild Cognitive Impairment | Caillaud M; Hudon C; Boller B; Brambati S; Duchesne S; Lorrain D; Gagnon JF; Maltezos S; Mellah S; Phillips N; Belleville S; | 31758692 CRDH |
| 18 | Associations between sensory loss and social networks, participation, support, and loneliness: Analysis of the Canadian Longitudinal Study on Aging. | Mick P, Parfyonov M, Wittich W, Phillips N, Guthrie D, Kathleen Pichora-Fuller M | 29358266 PSYCHOLOGY |
| 19 | The Effects of Age and Hearing Loss on Dual-Task Balance and Listening. | Bruce H, Aponte D, St-Onge N, Phillips N, Gagné JP, Li KZH | 28486677 PERFORM |
| Title: | Biomarkers | ||||
| Authors: | Grant N, Phillips N | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/39785420/ | ||||
| DOI: | 10.1002/alz.091882 | ||||
| Publication: | Alzheimer s & dementia : the journal of the Alzheimer s Association | ||||
| Keywords: | |||||
| PMID: | 39785420 | Category: | Date Added: | 2025-01-09 | |
| Dept Affiliation: |
CONCORDIA
1 Concordia University, Montreal, QC, Canada. |
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Description: |
Background: Hearing loss (HL) is a risk factor for dementia that is prevalent in older adults. Altered brain connectivity is present in individuals with HL, individuals with subjective cognitive decline (SCD), and individuals with mild cognitive impairment (MCI). In individuals with HL, altered brain connectivity has been associated with impaired scores on cognitive tests. In individuals with MCI, altered brain connectivity has been associated with degree of cognitive impairment and progression to dementia. Therefore, altered brain connectivity is a potential mechanism by which HL is associated with increased dementia risk. Methods: Data are from the Comprehensive Assessment of Neurodegeneration in Dementia study (Data Release 6, May 2023). Participants include cognitively unimpaired (CU, n=78, age=69.5), %female=77%), SCD (n=85, age=70.0, %female=74%), and MCI (n=159, age=72.2), %female=40%) individuals. Independent component analysis was used to identify the default-mode network (DMN), a resting-state network that is altered in individuals at risk for dementia. Hearing data include a pure-tone hearing screening protocol and speech-in-noise perception. Based on the pure-tone hearing screening, participants were classified as having normal hearing (NH) or HL. In each diagnostic group (CU, SCD, MCI), analyses of covariance compared DMN connectivity between the NH and HL participants and linear regressions evaluated the relationship between speech-in-noise perception and DMN connectivity. Results: Preliminary results are available for 94 older adults with MCI (NH = 60, pure-tone HL=34). Compared to individuals with MCI and NH, those with MCI and HL had decreased connectivity between the DMN and the caudate and thalamus. There was no relationship between DMN connectivity and speech-in-noise perception. The CU and SCI groups are expected to have a greater capacity for compensatory changes in functional connectivity. Therefore, it is expected that in the CU and SCI groups, pure-tone HL and speech-in-noise perception will be associated with increased DMN connectivity. Conclusion: Current results suggest that the increased dementia risk associated with HL may be due to decreased DMN connectivity and that pure-tone HL and speech-in-noise perception are differentially related to DMN connectivity. Future research will determine whether the relationship between hearing and DMN connectivity differs between older adults with varying risk of cognitive impairment. |
