Keyword search (4,163 papers available)

"Perrault AA" Authored Publications:

Title Authors PubMed ID
1 The effectiveness of Cognitive behavioral therapy for insomnia on sleep EEG hyperarousal: a multicentric polysomnographic study Sforza M; Morin CM; Dang-Vu TT; Pomares FB; Perrault AA; Gouin JP; Bušková J; Janku K; Vgontzas A; Fernandez-Mendoza J; Bastien CH; Riemann D; Baglioni C; Carollo G; Casoni F; Zucconi M; Castronovo V; Galbiati A; Ferini-Strambi L; 41688421
SOH
2 Effects of cognitive-behavioral therapy for insomnia during sedative-hypnotics withdrawal on sleep and cognition in older adults Barbaux L; Cross NE; Perrault AA; Es-Sounni M; Desrosiers C; Clerc D; Andriamampionona F; Lussier D; Tannenbaum C; Guimond A; Grenier S; Gouin JP; Dang-Vu TT; 41092866
SOH
3 Identification of five sleep-biopsychosocial profiles with specific neural signatures linking sleep variability with health, cognition, and lifestyle factors Perrault AA; Kebets V; Kuek NMY; Cross NE; Tesfaye R; Pomares FB; Li J; Chee MWL; Dang-Vu TT; Yeo BTT; 41056215
HKAP
4 Effect of chronic benzodiazepine and benzodiazepine receptor agonist use on sleep architecture and brain oscillations in older adults with chronic insomnia Barbaux L; Perrault AA; Cross NE; Weiner OM; Es-Sounni M; Pomares FB; Tarelli L; McCarthy M; Maltezos A; Smith D; Gong K; O' Byrne J; Yue V; Desrosiers C; Clerc D; Andriamampionona F; Lussier D; Gilbert S; Tannenbaum C; Gouin JP; Dang-Vu TT; 40570297
CSBN
5 Phase-Amplitude Coupling of NREM Sleep Oscillations Shows Between-Night Stability and is Related to Overnight Memory Gains Cross N; O' Byrne J; Weiner OM; Giraud J; Perrault AA; Dang-Vu TT; 40214027
PERFORM
6 Cognitive-behavioural therapy for insomnia mechanism of action: Exploring the homeostatic K-complex involvement Sforza M; Morin CM; Dang-Vu TT; Pomares FB; Perrault AA; Gouin JP; Bušková J; Janku K; Vgontzas A; Fernandez-Mendoza J; Bastien CH; Riemann D; Baglioni C; Carollo G; Casoni F; Zucconi M; Castronovo V; Galbiati A; Ferini-Strambi L; 39739397
SOH
7 NREM sleep brain networks modulate cognitive recovery from sleep deprivation Lee K; Wang Y; Cross NE; Jegou A; Razavipour F; Pomares FB; Perrault AA; Nguyen A; Aydin Ü; Uji M; Abdallah C; Anticevic A; Frauscher B; Benali H; Dang-Vu TT; Grova C; 39005401
PERFORM
8 A multidimensional investigation of sleep and biopsychosocial profiles with associated neural signatures Perrault AA; Kebets V; Kuek NMY; Cross NE; Tesfaye R; Pomares FB; Li J; Chee MWL; Dang-Vu TT; Yeo BTT; 38659875
HKAP
9 A Pilot Randomized Trial of Combined Cognitive-Behavioral Therapy and Exercise Training Versus Exercise Training Alone for the Management of Chronic Insomnia in Obstructive Sleep Apnea Cammalleri A; Perrault AA; Hillcoat A; Carrese-Chacra E; Tarelli L; Patel R; Baltzan M; Chouchou F; Dang-Vu TT; Gouin JP; Pepin V; 38663849
PERFORM
10 A multidimensional investigation of sleep and biopsychosocialprofiles with associated neural signatures Perrault AA; Kebets V; Kuek NMY; Cross NE; Tesfaye R; Pomares FB; Li J; Chee MWL; Dang-Vu TT; Thomas Yeo BT; 38559143
HKAP
11 Methodological approach to sleep state misperception in insomnia disorder: Comparison between multiple nights of actigraphy recordings and a single night of polysomnography recording Maltezos A; Perrault AA; Walsh NA; Phillips EM; Gong K; Tarelli L; Smith D; Cross NE; Pomares FB; Gouin JP; Dang-Vu TT; 38325157
HKAP
12 Effects of cognitive behavioral therapy for insomnia on subjective and objective measures of sleep and cognition Perrault AA; Pomares FB; Smith D; Cross NE; Gong K; Maltezos A; McCarthy M; Madigan E; Tarelli L; McGrath JJ; Savard J; Schwartz S; Gouin JP; Dang-Vu TT; 35691208
PERFORM
13 An altered balance of integrated and segregated brain activity is a marker of cognitive deficits following sleep deprivation Cross NE; Pomares FB; Nguyen A; Perrault AA; Jegou A; Uji M; Lee K; Razavipour F; Ali OBK; Aydin U; Benali H; Grova C; Dang-Vu TT; 34735431
PERFORM
14 Data-driven beamforming technique to attenuate ballistocardiogram artefacts in electroencephalography-functional magnetic resonance imaging without detecting cardiac pulses in electrocardiography recordings Uji M; Cross N; Pomares FB; Perrault AA; Jegou A; Nguyen A; Aydin U; Lina JM; Dang-Vu TT; Grova C; 34101939
PERFORM
15 Cortical gradients of functional connectivity are robust to state-dependent changes following sleep deprivation. Cross N; Paquola C; Pomares FB; Perrault AA; Jegou A; Nguyen A; Aydin U; Bernhardt BC; Grova C; Dang-Vu TT; 33186718
PERFORM

 

Title:Effects of cognitive-behavioral therapy for insomnia during sedative-hypnotics withdrawal on sleep and cognition in older adults
Authors:Barbaux LCross NEPerrault AAEs-Sounni MDesrosiers CClerc DAndriamampionona FLussier DTannenbaum CGuimond AGrenier SGouin JPDang-Vu TT
Link:pubmed.ncbi.nlm.nih.gov/41092866/
DOI:10.1016/j.sleep.2025.106826
Publication:Sleep medicine
Keywords:AgeingCBTiCognitionSedative-hypnotics withdrawalSpindleSubjective sleep
PMID:41092866 Category: Date Added:2025-10-16
Dept Affiliation: SOH
1 Sleep, Cognition and Neuroimaging Lab, Department of Health, Kinesiology and Applied Physiology, School of Health & Center for Studies in Behavioural Neurobiology, Concordia University, Montreal, Quebec, Canada; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, CIUSSS Centre-Sud-de-l'Ile-de-Montréal, Québec, Canada. Electronic address: loicbrb@gmail.com.2 Sleep, Cognition and Neuroimaging Lab, Department of Health, Kinesiology and Applied Physiology, School of Health & Center for Studies in Behavioural Neurobiology, Concordia University, Montreal, Quebec, Canada; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, CIUSSS Centre-Sud-de-l'Ile-de-Montréal, Québec, Canada; School of Psychology, University of Sydney, NSW, Australia.3 Sleep, Cognition and Neuroimaging Lab, Department of Health, Kinesiology and Applied Physiology, School of Health & Center for Studies in Behavioural Neurobiology, Concordia University, Montreal, Quebec, Canada; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, CIUSSS Centre-Sud-de-l'Ile-de-Montréal, Québec, Canada; Sleep and Circadian Group, Woolcock Institute of Medical Research and Macquarie University, Sydney, NSW, Australia.4 Sleep, Cognition and Neuroimaging Lab, Department of Health, Kinesiology and Applied Physiology, School of Health & Center for Studies in Behavioural Neurobiology, Concordia University, Montreal, Quebec, Canada; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, CIUSSS Centre-Sud-de-l'Ile-de-Montréal, Québec, Canada.5 Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, CIUSSS Centre-Sud-de-l'Ile-de-Montréal, Québec, Canada.6 Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, CIUSSS Centre-Sud-de-l'Ile-de-Montréal, Québec, Canada; Department of Psychology, University of Montreal, Quebec, Canada.7 Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, CIUSSS Centre-Sud-de-l'Ile-de-Montréal, Québec, Canada; Stress, Interpersonal Relationship and Health Lab, Department of Psychology & Centre for Clinical Research in Health, Concordia University, Quebec, Canada.8 Sleep, Cognition and Neuroimaging Lab, Department of Health, Kinesiology and Applied Physiology, School of Health & Center for Studies in Behavioural Neurobiology, Concordia University, Montreal, Quebec, Canada; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, CIUSSS Centre-Sud-de-l'Ile-de-Montréal, Québec, Canada. Electronic address: tt.dangvu@concordia.ca.

Description:

Objectives: Our objective was to assess the effect of cognitive-behavioral therapy for insomnia (CBTi) on subjective and objective sleep quality (including sleep spindles) and cognition during a sedative-hypnotics withdrawal program in older adults with insomnia disorder.

Methods: We performed a two-arm randomized controlled trial (RCT) of a sedative-hypnotic withdrawal plan alone (WPo group) or combined with CBTi (WP + CBTi group) in 47 older adults with insomnia disorder over a sixteen-week period. Our primary outcomes were change in self-reported insomnia severity (Insomnia Severity Index (ISI)), sleep efficiency (SE) from sleep diaries, and change in SE and spindle density from polysomnographic (PSG) recordings collected at baseline and at post-intervention (16 weeks). Secondary outcomes included other sleep changes from PSG, actigraphy and sleep diaries, sleep and mood questionnaires and neuropsychological assessments (manual dexterity, attention/concentration, verbal inhibition, visuo-spatial abilities).

Results: The withdrawal program was effective in achieving discontinuation and reducing insomnia severity, with similar success with and without CBTi. The combined intervention additionally improved subjective sleep quality and prevented the decrease in subjective sleep duration induced by sedative-hypnotic discontinuation. Neither intervention significantly impacted objective sleep architecture or cognitive performance. Furthermore, reduction in sleep spindle density was observed with combined CBTi and withdrawal, but not with withdrawal alone.

Conclusions: Both withdrawal alone and sedative-hypnotic withdrawal combined with CBTi effectively facilitated discontinuation and reduced insomnia severity, with the combined intervention further enhancing subjective sleep quality and preserving sleep duration. Although neither approach significantly impacted objective sleep architecture or cognitive performance, the potential reduction in sleep spindle density linked to the combined intervention warrants further investigation.




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