Keyword search (4,164 papers available)

"Orange JB" Authored Publications:

Title Authors PubMed ID
1 Development and validation of risk of CPS decline (RCD): a new prediction tool for worsening cognitive performance among home care clients in Canada Guthrie DM; Williams N; O' Rourke HM; Orange JB; Phillips N; Pichora-Fuller MK; Savundranayagam MY; Sutradhar R; 38041046
CRDH
2 Hearing loss is associated with gray matter differences in older adults at risk for and with Alzheimer's disease Giroud N; Pichora-Fuller MK; Mick P; Wittich W; Al-Yawer F; Rehan S; Orange JB; Phillips NA; 36911511
CRDH
3 A Newly Identified Impairment in Both Vision and Hearing Increases the Risk of Deterioration in Both Communication and Cognitive Performance Guthrie DM; Williams N; Campos J; Mick P; Orange JB; Pichora-Fuller MK; Savundranayagam MY; Wittich W; Phillips NA; 35859361
PSYCHOLOGY
4 Hearing and Cognitive Impairments Increase the Risk of Long-term Care Admissions Williams N; Phillips NA; Wittich W; Campos JL; Mick P; Orange JB; Pichora-Fuller MK; Savundranayagam MY; Guthrie DM; 31911955
PSYCHOLOGY

 

Title:Hearing loss is associated with gray matter differences in older adults at risk for and with Alzheimer's disease
Authors:Giroud NPichora-Fuller MKMick PWittich WAl-Yawer FRehan SOrange JBPhillips NA
Link:https://pubmed.ncbi.nlm.nih.gov/36911511/
DOI:10.1016/j.nbas.2021.100018
Publication:Aging brain
Keywords:Alzheimer's dementiaCLSAHearing lossMild cognitive impairmentSubjective cognitive decline
PMID:36911511 Category: Date Added:2023-03-13
Dept Affiliation: CRDH
1 Department of Psychology, Centre for Research in Human Development, Concordia University, Montréal, Québec, Canada.
2 Centre for Research on Brain, Language, and Music, Montréal, Québec, Canada.
3 Department of Psychology, University of Toronto, Mississauga, Ontario, Canada.
4 Department of Surgery, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
5 School of Optometry, Université de Montréal, Montreal, Quebec, Canada.
6 School of Communication Sciences and Disorders, Western University, London, Canada.
7 Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada.

Description:

Using data from the COMPASS-ND study we investigated associations between hearing loss and hippocampal volume as well as cortical thickness in older adults with subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer's dementia (AD). SCD participants with greater pure-tone hearing loss exhibited lower hippocampal volume, but more cortical thickness in the left superior temporal gyrus and right pars opercularis. Greater speech-in-noise reception thresholds were associated with lower cortical thickness bilaterally across much of the cortex in AD. The AD group also showed a trend towards worse speech-in-noise thresholds compared to the SCD group.





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