PERFORM Publications

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Title		Authors	PubMed ID
1	Empowering Melatonin Therapeutics with Drosophila Models	Millet-Boureima C; Ennis CC; Jamison J; McSweeney S; Park A; Gamberi C;	34698120 BIOLOGY
2	The Biology of Vasopressin.	Sparapani S, Millet-Boureima C, Oliver J, Mu K, Hadavi P, Kalostian T, Ali N, Avelar CM, Bardies M, Barrow B, Benedikt M, Biancardi G, Bindra R, Bui L, Chihab Z, Cossitt A, Costa J, Daigneault T, Dault J, Davidson I, Dias J, Dufour E, El-Khoury S, Farhangdoost N, Forget A, Fox A, Gebrael M, Gentile MC, Geraci O, Gnanapragasam A, Gomah E, Haber E, Hamel C, Iyanker T, Kalantzis C, Kamali S, Kassardjian E, Kontos HK, Le TBU, LoScerbo D, Low YF, Mac Rae D, Maurer F, Mazhar S, Nguyen A, Nguyen-Duong K, Osborne-L	33477721 BIOLOGY
3	Cyst Reduction by Melatonin in a Novel Drosophila Model of Polycystic Kidney Disease.	Millet-Boureima C; Rozencwaig R; Polyak F; Gamberi C;	33238462 BIOLOGY
4	Drug discovery and chemical probing in Drosophila.	Millet-Boureima C, Selber-Hnatiw S, Gamberi C	32551911 BIOLOGY
5	Cyst Reduction in a Polycystic Kidney Disease Drosophila Model Using Smac Mimics.	Millet-Boureima C, Chingle R, Lubell WD, Gamberi C	31635379 BIOLOGY
6	Modeling Renal Disease "On the Fly".	Millet-Boureima C, Porras Marroquin J, Gamberi C	29955604 BIOLOGY

Title:	Modeling Renal Disease "On the Fly".
Authors:	Millet-Boureima C, Porras Marroquin J, Gamberi C
Link:	https://www.ncbi.nlm.nih.gov/pubmed/29955604?dopt=Abstract
DOI:	10.1155/2018/5697436
Publication:	BioMed research international
Keywords:
PMID:	29955604	Category:	Biomed Res Int	Date Added:	2019-06-07
Dept Affiliation:	BIOLOGY 1 Biology Department, Concordia University, Montreal, QC, Canada.

Description:

Modeling Renal Disease "On the Fly".

Biomed Res Int. 2018;2018:5697436

Authors: Millet-Boureima C, Porras Marroquin J, Gamberi C

Abstract

Detoxification is a fundamental function for all living organisms that need to excrete catabolites and toxins to maintain homeostasis. Kidneys are major organs of detoxification that maintain water and electrolyte balance to preserve physiological functions of vertebrates. In insects, the renal function is carried out by Malpighian tubules and nephrocytes. Due to differences in their circulation, the renal systems of mammalians and insects differ in their functional modalities, yet carry out similar biochemical and physiological functions and share extensive genetic and molecular similarities. Evolutionary conservation can be leveraged to model specific aspects of the complex mammalian kidney function in the genetic powerhouse Drosophila melanogaster to study how genes interact in diseased states. Here, we compare the human and Drosophila renal systems and present selected fly disease models.

PMID: 29955604 [PubMed - indexed for MEDLINE]

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