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PubMed Publications| Keyword search (4,163 papers available) |  |
"Mick P" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Clinical Manifestations | Rehan S; Mehrabi F; Mick P; Phillips NA; | 41447555 CONCORDIA |
| 2 | Does social connection mediate the association between neuroticism and cognition? Cross-sectional analysis of the Canadian Longitudinal Study on Aging | Bethell J; Andrew MK; Hothi S; Mick P; Morgan D; O' Connell ME; Phillips NA; Stewart S; Walker JD; Wittich W; McGilton KS; | 37667914 CRDH |
| 3 | Hearing loss is associated with gray matter differences in older adults at risk for and with Alzheimer's disease | Giroud N; Pichora-Fuller MK; Mick P; Wittich W; Al-Yawer F; Rehan S; Orange JB; Phillips NA; | 36911511 CRDH |
| 4 | Sex-Specific Interactions Between Hearing and Memory in Older Adults With Mild Cognitive Impairment: Findings From the COMPASS-ND Study | Al-Yawer F; Pichora-Fuller MK; Wittich W; Mick P; Giroud N; Rehan S; Phillips NA; | 36607746 PSYCHOLOGY |
| 5 | Sex-Linked Biology and Gender-Related Research Is Essential to Advancing Hearing Health | Reavis KM; Bisgaard N; Canlon B; Dubno JR; Frisina RD; Hertzano R; Humes LE; Mick P; Phillips NA; Pichora-Fuller MK; Shuster B; Singh G; | 36384870 PSYCHOLOGY |
| 6 | A Newly Identified Impairment in Both Vision and Hearing Increases the Risk of Deterioration in Both Communication and Cognitive Performance | Guthrie DM; Williams N; Campos J; Mick P; Orange JB; Pichora-Fuller MK; Savundranayagam MY; Wittich W; Phillips NA; | 35859361 PSYCHOLOGY |
| 7 | Hearing and Cognitive Impairments Increase the Risk of Long-term Care Admissions | Williams N; Phillips NA; Wittich W; Campos JL; Mick P; Orange JB; Pichora-Fuller MK; Savundranayagam MY; Guthrie DM; | 31911955 PSYCHOLOGY |
| 8 | Sensory-cognitive associations are only weakly mediated or moderated by social factors in the Canadian Longitudinal Study on Aging. | Hämäläinen A, Phillips N, Wittich W, Pichora-Fuller MK, Mick P | 31873079 PSYCHOLOGY |
| 9 | Detection of vision and /or hearing loss using the interRAI Community Health Assessment aligns well with common behavioral vision/hearing measurements. | Urqueta Alfaro A, Guthrie DM, Phillips NA, Pichora-Fuller MK, Mick P, McGraw C, Wittich W | 31581243 PSYCHOLOGY |
| 10 | Associations between sensory loss and social networks, participation, support, and loneliness: Analysis of the Canadian Longitudinal Study on Aging. | Mick P, Parfyonov M, Wittich W, Phillips N, Guthrie D, Kathleen Pichora-Fuller M | 29358266 PSYCHOLOGY |
| Title: | Clinical Manifestations | ||||
| Authors: | Rehan S, Mehrabi F, Mick P, Phillips NA | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/41447555/ | ||||
| DOI: | 10.1002/alz70857_105917 | ||||
| Publication: | Alzheimer s & dementia : the journal of the Alzheimer s Association | ||||
| Keywords: | |||||
| PMID: | 41447555 | Category: | Date Added: | 2025-12-25 | |
| Dept Affiliation: |
CONCORDIA
1 Concordia University, Montreal, QC, Canada. 2 University of Saskatchewan, Saskatoon, SK, Canada. |
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Description: |
Background: Sensory and psychosocial factors are potentially modifiable risk factors for dementia. Social factors and indicators of mental health are associated with cognitive performance and risk for Alzheimer's disease (AD). Sensory impairment can lead to communication and mobility difficulties, reducing social engagement and possibly accelerating cognitive decline. We aimed to 1) characterize sensory and psychosocial function in groups with (or at risk for) AD and 2) test whether psychosocial factors and group membership moderate the sensory-cognitive relationship. Method: We used data from the Comprehensive Assessment of Neurodegeneration and Dementia (COMPASS-ND) study (Release 7) to assess sensory, psychosocial, and cognitive function in cognitively normal controls (N = 123, MAge=69.7, 76% female), individuals with mild cognitive impairment (MCI, N = 348, MAge=73.2, 42% female), or with mild AD (N = 151, MAge=75.1, 41% female). Sensory loss was measured using speech-reception thresholds (hearing) and contrast sensitivity (vision). Psychosocial factors (depression, anxiety, quality of life, social support, social isolation) were assessed via self-reported questionnaires. Cognitive function was evaluated using scores on neuropsychological tests (memory, executive function, verbal fluency, processing speed). Correlation analyses were done to assess sensory, psychosocial, and cognitive function for all groups. For moderated moderation analyses, we examined the three-way interaction of psychosocial factors and diagnostic group on cognitive performance, controlling for age, sex, education, and income. Result: Hearing loss was more prevalent in those with MCI (42%) and AD (48%) compared to controls (27%), as was low contrast sensitivity (4% controls, 20% MCI, 37% AD). Compared to controls, individuals with MCI and AD reported worse psychosocial function (e.g., depression, anxiety, lower quality of life) and reduced social engagement. Moderation analyses indicated that poor psychosocial function (e.g., social isolation, depressive or anxiety symptoms) amplified the sensory-cognitive association in individuals with MCI, compared to controls and those with AD. Conclusion: Psychosocial function moderates the relationship between sensory loss and cognitive function differently across diagnostic groups. Particularly, individuals with MCI show the strongest relationship between sensory and cognitive function at poor levels of psychosocial function. Our research explored sensory-psychosocial-cognitive interactions in groups with varying degrees of cognitive impairment, laying the groundwork for understanding how sensory loss and psychosocial deficits contribute to cognitive decline. |
