| Keyword search (4,163 papers available) | ![]() |
"Messina C" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Regioselective Stepwise Synthesis of Unsymmetrical 1,2,5-Triarylpyrroles via Palladium-Catalyzed Decarboxylative Cross-Coupling and C-H Arylation | Buonomano C; Patterson S; Ngou JS; Messina C; Taylor S; Bilodeau F; Forgione P; | 41900086 CHEMBIOCHEM |
| 2 | A Modular and Regioselective Synthesis of Di- and Triarylated Thiophenes: Strategies for Accessing Challenging Isomeric Motifs | Messina C; McKibbon K; Wong KS; Prevost P; Petkov V; Forgione P; | 41160050 CONCORDIA |
| 3 | Diverse Applications of Biomass-Derived 5-Hydroxymethylfurfural and Derivatives as Renewable Starting Materials | Chacón-Huete F; Messina C; Cigana B; Forgione P; | 35652539 CHEMBIOCHEM |
| 4 | Programmed Synthesis of Tetra-Aryl Thiophenes with Stepwise, Ester-Controlled Regioselectivity | Messina C; Ottenwaelder X; Forgione P; | 34506149 CHEMBIOCHEM |
| Title: | Programmed Synthesis of Tetra-Aryl Thiophenes with Stepwise, Ester-Controlled Regioselectivity | ||||
| Authors: | Messina C, Ottenwaelder X, Forgione P | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/34506149/ | ||||
| DOI: | 10.1021/acs.orglett.1c02447 | ||||
| Publication: | Organic letters | ||||
| Keywords: | |||||
| PMID: | 34506149 | Category: | Date Added: | 2021-09-11 | |
| Dept Affiliation: |
CHEMBIOCHEM
1 Department of Chemistry and Biochemistry, Concordia University, Montreal, Quebec H4B 1R6, Canada. |
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Description: |
Herein, we report a modular synthetic route to access tetra-arylated thiophene compounds with four different substituents with programmed chemical control provided by an ester activating/directing group. This method enables the functionalization of individual positions of thiophene sequentially via regioselective halogenations and cross-coupling reactions. The reaction sequence described provides tetra-arylated thiophenes in higher yields than previous routes and employs practical reaction protocols, simple catalytic systems, and short reaction times. |



