PERFORM Publications

Keyword search (4,163 papers available)

Title		Authors	PubMed ID
1	Mechanochemically-mediated dynamic imine bond conjugation for drug delivery using carbon dots	Fuoco G; Mandl GA; De Mesa C; Capobianco JA; Naccache R;	41288467 CHEMBIOCHEM
2	Enhancing X-ray Activated Photodynamic Therapy with Supported Lipid Bilayer-Coated Radioluminescent Nanoparticles	Bondon N; Mandl GA; Mena-Giraldo P; Ferron Z; Sadeghipour N; DeWolf C; Capobianco JA;	41059546 CNSR
3	A Spike-Accum bioconjugate protein vaccine confers potent SARS-CoV-2-specific immunity	Pierre Bikorimana J; Caveney NA; El-Hachem N; Mandl GA; Capobianco JA; Stanga D; Abusarah J; Hancock MA; Farah R; Gonçalves MP; Falzarano D; Liao M; Hamonic G; Liu Q; Beaudoin S; Talbot S; Rafei M;	41054531 CNSR
4	Light-Activated Micromotors in Air Propelled by Thermal Convection	Mena-Giraldo P; Mandl GA; Quezada-Novoa V; Garcia-Henao C; Bondon N; Hazlett MJ; Capobianco JA;	40964823 CNSR
5	Upconversion Lanthanide-Based 2D Metal-Organic Frameworks for Multimode Information Encryption	Chen J; Xie Y; Yang W; Sun R; Xing F; Mandl GA; Capobianco JA; Sun L;	40557752 CNSR
6	Janus Micromotors for Photophoretic Motion and Photon Upconversion Applications Using a Single Near-Infrared Wavelength	Mena-Giraldo P; Kaur M; Maurizio SL; Mandl GA; Capobianco JA;	38197400 CHEMBIOCHEM
7	Achieving photostability in dye-sensitized upconverting nanoparticles and their use in Fenton type photocatalysis	Kaur M; Maurizio SL; Mandl GA; Capobianco JA;	37552506 CHEMBIOCHEM
8	The role of lanthanide luminescence in advancing technology	Tessitore G; Mandl GA; Maurizio SL; Kaur M; Capobianco JA;	37323462 CHEMBIOCHEM
9	Combining Pr3+-Doped Nanoradiosensitizers and Endogenous Protoporphyrin IX for X-ray-Mediated Photodynamic Therapy of Glioblastoma Cells	Mandl GA; Vettier F; Tessitore G; Maurizio SL; Bietar K; Stochaj U; Capobianco JA;	37267436 CHEMBIOCHEM
10	Cooperative Sensitization Upconversion in Solution Dispersions of Co-Crystal Assemblies of Mononuclear Yb3+ and Eu3+ Complexes	Sun G; Xie Y; Wang Y; Mandl GA; Maurizio SL; Zhang H; Ottenwaelder X; Capobianco JA; Sun L;	37040148 CNSR
11	Biomolecules incorporated in halide perovskite nanocrystals: synthesis, optical properties, and applications	Aminzare M; Jiang J; Mandl GA; Mahshid S; Capobianco JA; Dorval Courchesne NM;	36722934 CHEMBIOCHEM
12	Upconversion Luminescence through Cooperative and Energy-Transfer Mechanisms in Yb3+ -Metal-Organic Frameworks	Xie Y; Sun G; Mandl GA; Maurizio SL; Chen J; Capobianco JA; Sun L;	36437239 CNSR
13	Investigating the reactive oxygen species production of Rose Bengal and Merocyanine 540-loaded radioluminescent nanoparticles	Nsubuga A; Mandl GA; Capobianco JA;	36132856 CNSR
14	On the photostability and luminescence of dye-sensitized upconverting nanoparticles using modified IR820 dyes	Kaur M; Mandl GA; Maurizio SL; Tessitore G; Capobianco JA;	36132705 CNSR
15	Evaluation of Lanthanide-Doped Upconverting Nanoparticles for in Vitro and in Vivo Applications	Samhadaneh DM; Mandl GA; Han Z; Mahjoob M; Weber SC; Tuznik M; Rudko DA; Capobianco JA; Stochaj U;	35025434 CNSR
16	Energy migration control of multi-modal emissions in an Er3+ doped nanostructure toward information encryption and deep learning decoding	Song Y; Lu M; Mandl GA; Xie Y; Sun G; Chen J; Liu X; Capobianco JA; Sun L;	34476872 ENCS
17	On a local (de-)trapping model for highly doped Pr3+ radioluminescent and persistent luminescent nanoparticles	Mandl GA; Van der Heggen D; Cooper DR; Joos JJ; Seuntjens J; Smet PF; Capobianco JA;	33030192 CNSR
18	A NIR-responsive azobenzene-based supramolecular hydrogel using upconverting nanoparticles.	Mandl GA, Rojas-Gutierrez PA, Capobianco JA	29726556 CNSR
19	Perspective: lanthanide-doped upconverting nanoparticles.	Mandl GA, Cooper DR, Hirsch T, Seuntjens J, Capobianco JA	30572318 CNSR
20	Recent insights into upconverting nanoparticles: spectroscopy, modeling, and routes to improved luminescence.	Tessitore G, Mandl GA, Brik MG, Park W, Capobianco JA	31120083 CNSR

Title:	Enhancing X-ray Activated Photodynamic Therapy with Supported Lipid Bilayer-Coated Radioluminescent Nanoparticles
Authors:	Bondon N, Mandl GA, Mena-Giraldo P, Ferron Z, Sadeghipour N, DeWolf C, Capobianco JA
Link:	https://pubmed.ncbi.nlm.nih.gov/41059546/
DOI:	10.1021/acs.langmuir.5c03152
Publication:	Langmuir : the ACS journal of surfaces and colloids
Keywords:
PMID:	41059546	Category:	Date Added:	2025-10-08
Dept Affiliation:	CNSR 1 Concordia University, Department of Chemistry and Biochemistry and Centre for Nanoscience Research, Montreal, Quebec H4B 1R6, Canada. 2 Département de Pharmacologie et Physiologie, Université de Montréal, Montreal, Québec H3T 1J4, Canada.

Description:

We report the synthesis of supported lipid bilayer (SLB)-coated radioluminescent nanoparticles (RLNPs) possessing a lanthanide-based core for low-dose X-ray activated photodynamic therapy (XPDT). Methylene blue (MB) photosensitizer molecules, incorporated within the SLB, are excited by energy transfer from europium, leading to an enhanced generation of reactive oxygen species by the XPDT effect. The stability and biophysical features of the bilayer coating were studied using Langmuir monolayers, as well as dynamic light scattering and zeta potential. MB loading within lipid bilayers was confirmed by pressure-area monolayer isotherms and quantified by fluorescence spectroscopy. In vitro XPDT studies were carried out on A549 lung cancer cells to characterize NP localization and cell damage. Notably, radiation enhancement ratios up to 4.6 were observed using a low radiation dose of 2 Gy and 200 µg mL^-1 SLB-MB-RLNPs illustrating their potential in low-dose XPDT.

BookR: School of Health Core Facilities Booking

"Mandl GA" Authored Publications:

Search Publications

No results