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"Mahmud A" Authored Publications:

Title Authors PubMed ID
1 The serial blocking effect: a testbed for the neural mechanisms of temporal-difference learning. Mahmud A; Petrov P; Esber GR; Iordanova MD; 30979910
CSBN

 

Title:The serial blocking effect: a testbed for the neural mechanisms of temporal-difference learning.
Authors:Mahmud APetrov PEsber GRIordanova MD
Link:https://www.ncbi.nlm.nih.gov/pubmed/30979910
DOI:10.1038/s41598-019-42244-4
Publication:
Keywords:
PMID:30979910 Category:Sci Rep Date Added:2019-05-31
Dept Affiliation: CSBN
1 Department of Psychology, Center for Studies in Behavioral Neurobiology/Groupe de recherche en neurobiologie comportementale, Concordia University, Montreal, Quebec, Canada.
2 Department of Psychology, Brooklyn College of the City University of New York, Brooklyn, NY, USA.
3 Department of Psychology, Center for Studies in Behavioral Neurobiology/Groupe de recherche en neurobiologie comportementale, Concordia University, Montreal, Quebec, Canada. mihaela.iordanova@concordia.ca.

Description:

Temporal-difference (TD) learning models afford the neuroscientist a theory-driven roadmap in the quest for the neural mechanisms of reinforcement learning. The application of these models to understanding the role of phasic midbrain dopaminergic responses in reward prediction learning constitutes one of the greatest success stories in behavioural and cognitive neuroscience. Critically, the classic learning paradigms associated with TD are poorly suited to cast light on its neural implementation, thus hampering progress. Here, we present a serial blocking paradigm in rodents that overcomes these limitations and allows for the simultaneous investigation of two cardinal TD tenets; namely, that learning depends on the computation of a prediction error, and that reinforcing value, whether intrinsic or acquired, propagates back to the onset of the earliest reliable predictor. The implications of this paradigm for the neural exploration of TD mechanisms are highlighted.

PMID: 30979910 [PubMed - indexed for MEDLINE]





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