BookR: School of Health Core Facilities Booking
PubMed Publications| Keyword search (4,164 papers available) |  |
"Léonard G" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Impact of different acute low back pain definitions on the predictors and on the risk of transition to chronic low back pain: a prospective longitudinal cohort study | Osagie RO; Tufa I; Angarita-Fonseca A; Pagé MG; Lacasse A; Stone LS; Rainville P; Roy M; Tétreault P; Fortin M; Léonard G; Massé-Alarie H; Roy JS; Grant AV; Meloto CB; | 40663110 HKAP |
| 2 | Low back pain definitions: effect on patient inclusion and clinical profiles | Massé-Alarie H; Angarita-Fonseca A; Lacasse A; Pagé MG; Tétreault P; Fortin M; Léonard G; Stone LS; Roy JS; | 35356510 HKAP |
| 3 | Anti-Dementia Drugs, Gait Performance and Mental Imagery of Gait: A Non-Randomized Open-Label Trial. | Beauchet O, Barden J, Liu-Ambrose T, Chester VL, Annweiler C, Szturm T, Grenier S, Léonard G, Bherer L, Allali G, Canadian Gait Consortium | 27568453 PERFORM |
| 4 | Association Between Falls and Brain Subvolumes: Results from a Cross-Sectional Analysis in Healthy Older Adults. | Beauchet O, Launay CP, Barden J, Liu-Ambrose T, Chester VL, Szturm T, Grenier S, Léonard G, Bherer L, Annweiler C, Helbostad JL, Verghese J, Allali G, Biomathics and Canadian Gait Consortium | 27785698 PERFORM |
| 5 | Noninvasive tongue stimulation combined with intensive cognitive and physical rehabilitation induces neuroplastic changes in patients with multiple sclerosis: A multimodal neuroimaging study. | Leonard G, Lapierre Y, Chen JK, Wardini R, Crane J, Ptito A | 28607750 PERFORM |
| Title: | Noninvasive tongue stimulation combined with intensive cognitive and physical rehabilitation induces neuroplastic changes in patients with multiple sclerosis: A multimodal neuroimaging study. | ||||
| Authors: | Leonard G, Lapierre Y, Chen JK, Wardini R, Crane J, Ptito A | ||||
| Link: | www.ncbi.nlm.nih.gov/pubmed/28607750?dopt=Abstract | ||||
| Publication: | |||||
| Keywords: | |||||
| PMID: | 28607750 | Category: | Mult Scler J Exp Transl Clin | Date Added: | 2019-04-15 |
| Dept Affiliation: |
PERFORM
1 Department of Neurology and Neurosurgery, Faculty of Medicine, McGill University, Canada; Cognitive Neuroscience, Montreal Neurological Institute, Canada. 2 Department of Neurology and Neurosurgery, Faculty of Medicine, McGill University, Canada; Neurology, Montreal Neurological Institute, Canada. 3 Concordia University, PERFORM Centre, Canada. |
||||
Description: |
Noninvasive tongue stimulation combined with intensive cognitive and physical rehabilitation induces neuroplastic changes in patients with multiple sclerosis: A multimodal neuroimaging study. Mult Scler J Exp Transl Clin. 2017 Jan-Mar;3(1):2055217317690561 Authors: Leonard G, Lapierre Y, Chen JK, Wardini R, Crane J, Ptito A Abstract BACKGROUND: Multiple sclerosis (MS) patients have central nervous system (CNS) lesions that may impede cognitive and sensorimotor function. Few rehabilitative therapies are available. OBJECTIVES: The objective of this paper is to study effects of noninvasive tongue stimulation using the Portable Neuromodulation Stimulator (PoNS) combined with intensive cognitive and physical rehabilitation on working memory, gait, balance and concomitant changes in the brain. METHODS: Fourteen MS patients, seven each in an active and a sham stimulation group, participated. Participants received intensive physical therapy and working memory training for 14 weeks. Functional magnetic resonance imaging (fMRI) using motor imagery and working-memory tasks were completed prior to and following therapy, as were sensory organization tests (SOT), motor performance measures, and neuropsychological assessment. RESULTS: On the SOT, the active group showed significant improvement from baseline. fMRI revealed significant blood oxygen level-dependent signal changes in the left primary motor cortex for the Active Group, while the sham group had increased activity in bilateral premotor cortices. All individuals improved on working-memory tasks, but only the active group showed increased dorsolateral prefrontal cortex activity. CONCLUSIONS: In this cohort of MS patients, the results suggest that PoNS stimulation can enhance motor performance and working memory while also driving neuroplasticity. Further studies are warranted to explore these findings. PMID: 28607750 [PubMed] |
