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PubMed Publications| Keyword search (4,163 papers available) |  |
"Kang MS" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Mesocorticolimbic function in cocaine polydrug users: A multimodal study of drug cue reactivity and cognitive regulation | Scala SG; Kang MS; Cox SML; Rosa-Neto P; Massarweh G; Leyton M; | 38221806 CSBN |
| 2 | Brain PET Imaging in Small Animals: Tracer Formulation, Data Acquisition, Image Reconstruction, and Data Analysis | Bdair H; Kang MS; Ottoy J; Aliaga A; Kunach P; Singleton TA; Blinder S; Soucy JP; Leyton M; Rosa-Neto P; Kostikov A; | 38006502 PERFORM |
| 3 | Radiosynthesis and In Vivo Evaluation of Four Positron Emission Tomography Tracer Candidates for Imaging of Melatonin Receptors | Bdair H; Singleton TA; Ross K; Jolly D; Kang MS; Aliaga A; Tuznik M; Kaur T; Yous S; Soucy JP; Massarweh G; Scott PJH; Koeppe R; Spadoni G; Bedini A; Rudko DA; Gobbi G; Benkelfat C; Rosa-Neto P; Brooks AF; Kostikov A; | 35420022 PERFORM |
| 4 | Topographical distribution of Aβ predicts progression to dementia in Aβ positive mild cognitive impairment | Pascoal TA, Therriault J, Mathotaarachchi S, Kang MS, Shin M, Benedet AL, Chamoun M, Tissot C, Lussier F, Mohaddes S, Soucy JP, Massarweh G, Gauthier S, Rosa-Neto P, | 32582834 PERFORM |
| 5 | Amyloid and tau signatures of brain metabolic decline in preclinical Alzheimer's disease. | Pascoal TA, Mathotaarachchi S, Shin M, Park AY, Mohades S, Benedet AL, Kang MS, Massarweh G, Soucy JP, Gauthier S, Rosa-Neto P, Alzheimer’s Disease Neuroimaging Initiative | 29396637 PERFORM |
| Title: | Brain PET Imaging in Small Animals: Tracer Formulation, Data Acquisition, Image Reconstruction, and Data Analysis | ||||
| Authors: | Bdair H, Kang MS, Ottoy J, Aliaga A, Kunach P, Singleton TA, Blinder S, Soucy JP, Leyton M, Rosa-Neto P, Kostikov A | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/38006502/ | ||||
| DOI: | 10.1007/978-1-0716-3499-8_16 | ||||
| Publication: | Methods in molecular biology (Clifton, N.J.) | ||||
| Keywords: | PET image acquisition; PET image analysis; PET image reconstruction; PET tracers; Positron emission tomography; Preclinical imaging; | ||||
| PMID: | 38006502 | Category: | Date Added: | 2023-11-26 | |
| Dept Affiliation: |
PERFORM
1 Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada. 2 Department of Psychiatry, McGill University, Montreal, QC, Canada. 3 McConnell Brain Imaging Centre, Montreal Neurological Institute-Hospital (The Neuro), McGill University, Montreal, QC, Canada. 4 Translational Neuroimaging Laboratory, Research Centre for Studies in Aging, Douglas Research Institute, McGill University, Montreal, QC, Canada. 5 LC Campbell Cognitive Neurology Unit, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada. 6 PERFORM Centre, Concordia University, Montreal, QC, Canada. 7 Department of Psychology, McGill University, Montreal, QC, Canada. 8 Center for Studies in Behavioral Neurobiology, Concordia University, Montreal, QC, Canada. 9 Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada. alexey.kostikov@mcgill.ca. 10 Translational Neuroimaging Laboratory, Research Centre for Studies in Aging, Douglas Research Institute, McGill University, Montreal, QC, Canada. alexey.kostikov@mcgill.ca. 11 McConnell Brain Imaging Centre, Montreal Neurological Institute-Hospital (The Neuro), McGill University, Montreal, QC, Canada. alexey.kostikov@mcgill.ca. 12 Department of Chemistry, McGill University, Montreal, QC, Canada. alexey.kostikov@mcgill.ca. |
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Description: |
Positron emission tomography (PET) is a noninvasive functional imaging modality that involves in vivo detection of spatiotemporal changes in the binding of radioactive pharmaceuticals (a.k.a. PET tracers) to their target sites in different organs. The development of new PET tracers commonly involves their preclinical evaluation in small rodents. Moreover, laboratory animal PET research is now being used with progressively greater frequency to complement human PET studies, to investigate in greater depth the underlying pathophysiology of human diseases, and to monitor the efficiency of novel therapeutic interventions. Here we describe the steps toward a successful small animal PET study, from tracer formulation and image acquisition to data reconstruction and analysis of the acquired scans, with a particular focus on its utility for the brain. |
