Keyword search (4,163 papers available)

"Kadem L" Authored Publications:

Title Authors PubMed ID
1 Hemodynamic performance and blood damage of the Intra-aortic pumps: A CFD-Based investigation Aycan O; Park Y; Kadem L; 41863715
ENCS
2 A high-fidelity simulator for evaluation of hemodynamic response during cardiopulmonary resuscitation in hypogravity environments Lord Z; Andrade C; Leroux L; Kadem L; 41741473
CHEMISTRY
3 Comprehensive review of reinforcement learning for medical ultrasound imaging Elmekki H; Islam S; Alagha A; Sami H; Spilkin A; Zakeri E; Zanuttini AM; Bentahar J; Kadem L; Xie WF; Pibarot P; Mizouni R; Otrok H; Singh S; Mourad A; 40567264
ENCS
4 Experimental Investigation of the Effect of a MitraClip on Left Ventricular Flow Dynamics Teimouri K; Darwish A; Saleh W; Ng HD; Kadem L; 40325266
ENCS
5 CACTUS: An open dataset and framework for automated Cardiac Assessment and Classification of Ultrasound images using deep transfer learning Elmekki H; Alagha A; Sami H; Spilkin A; Zanuttini AM; Zakeri E; Bentahar J; Kadem L; Xie WF; Pibarot P; Mizouni R; Otrok H; Singh S; Mourad A; 40107020
ENCS
6 Numerical investigation of the flow induced by a transcatheter intra-aortic entrainment pump Park Y; Aycan O; Kadem L; 40014031
ENCS
7 Design, manufacturing, and multi-modal imaging of stereolithography 3D printed flexible intracranial aneurysm phantoms Yalman A; Jafari A; Léger É; Mastroianni MA; Teimouri K; Savoji H; Collins DL; Kadem L; Xiao Y; 39546636
BIOLOGY
8 Design and validation of an In Vitro test bench for the investigation of cardiopulmonary resuscitation procedure El-Khoury A; Leroux L; Dupuis Desroches J; Di Labbio G; Kadem L; 39305857
ENCS
9 An Anatomically Shaped Mitral Valve for Hemodynamic Testing Darwish A; Papolla C; Rieu R; Kadem L; 38228812
ENCS
10 Spectral-Clustering of Lagrangian Trajectory Graphs: Application to Abdominal Aortic Aneurysms Darwish A; Norouzi S; Kadem L; 34845627
ENCS
11 On Left Ventricle Stroke Work Efficiency in Children with Moderate Aortic Valve Regurgitation or Moderate Aortic Valve Stenosis Asaadi M; Mawad W; Djebbari A; Keshavardz-Motamed Z; Dahdah N; Kadem L; 34357415
ENCS
12 Response to: "Color Doppler Splay: a New Tool for the Assessment of Valvular Regurgitations?" by Allievi et al Wiener PC; Friend EJ; Bhargav R; Radhakrishnan K; Kadem L; Pressman GS; 34062241
ENCS
13 Energy loss associated with in-vitro modeling of mitral annular calcification. Wiener PC, Darwish A, Friend E, Kadem L, Pressman GS 33591991
ENCS
14 Proper Orthogonal Decomposition Analysis of the Flow Downstream of a Dysfunctional Bileaflet Mechanical Aortic Valve. Darwish A, Di Labbio G, Saleh W, Kadem L 33469847
ENCS
15 Impact of Mitral Regurgitation on the Flow in a Model of a Left Ventricle. Papolla C, Darwish A, Kadem L, Rieu R 33000444
ENCS
16 Color Doppler Splay: A Clue to the Presence of Significant Mitral Regurgitation. Wiener PC, Friend EJ, Bhargav R, Radhakrishnan K, Kadem L, Pressman GS 32712051
ENCS
17 Effects of Hemodynamic Conditions and Valve Sizing on Leaflet Bending Stress in Self-Expanding Transcatheter Aortic Valve: An In-vitro Study. Stanová V, Zenses AS, Thollon L, Kadem L, Barragan P, Rieu R, Pibarot P 31995230
ENCS
18 Experimental Investigation of the Effect of Heart Rate On Flow in the Left Ventricle in Health and Disease -- Aortic Valve Regurgitation. Di Labbio G, Ben-Assa E, Kadem L 31701119
ENCS
19 Jet collisions and vortex reversal in the human left ventricle. Di Labbio G, Kadem L 30049450
ENCS
20 Response to letter to the editor: 'Left ventricular flow in the presence of aortic regurgitation'. Di Labbio G, Kadem L 30871721
ENCS
21 Experimental investigation of the flow downstream of a dysfunctional bileaflet mechanical aortic valve. Darwish A, Di Labbio G, Saleh W, Smadi O, Kadem L 31066923
ENCS

 

Title:Impact of Mitral Regurgitation on the Flow in a Model of a Left Ventricle.
Authors:Papolla C,  Darwish A,  Kadem L,  Rieu R
Link:https://www.ncbi.nlm.nih.gov/pubmed/33000444
DOI:10.1007/s13239-020-00490-y
Publication:Cardiovascular engineering and technology
Keywords:In vitro study;  Left ventricle flow;  Mitral valve regurgitation;  Particle image velocimetry;  Viscous energy dissipation; 
PMID:33000444 Category:Cardiovasc Eng Technol Date Added:2020-10-02
Dept Affiliation: ENCS
1 Aix-Marseille University, Gustave Eiffel University, LBA UMR_T 24, Marseille, France.
2 Képhalios, part of Affluent Medical Group, Aix-en-Provence, France.
3 Laboratory of Cardiovascular Fluid Dynamics, Mechanical, Industrial and Aerospace Engineering, Concordia University, Montréal, QC, Canada.
4 Aix-Marseille University, Gustave Eiffel University, LBA UMR_T 24, Marseille, France. regis.rieu@univ-amu.fr.
5 Laboratoire de Biomécanique Appliquée, Bd. P. Dramard, Faculté de Medecine secteur-Nord, 13916, Marseille Cedex 20, France. regis.rieu@univ-amu.fr.

Description:

Impact of Mitral Regurgitation on the Flow in a Model of a Left Ventricle.

Cardiovasc Eng Technol. 2020 Sep 30; :

Authors: Papolla C, Darwish A, Kadem L, Rieu R

Abstract

PURPOSE: Mitral regurgitation (MR) is the second most common valve disease in industrialized countries. Despite its high prevalence, little is known about its impact on the flow dynamics in the left ventricle (LV). Because of the interdependence between valvular function and hemodynamics in the heart chambers, an exploration of the dynamics in the LV could lead to a diagnosis of MR. This in vitro study aimed to develop an advanced left heart simulator capable of reproducing several conditions of MR and to evaluate their impact on the LV flow dynamics in terms of flow structures and viscous energy dissipation (VED).

METHODS: A simulator, previously developed to test mechanical and biological valves, was upgraded with an original anatomically-shaped mitral valve made from a hydrogel. The valve can be used in healthy or pathological configurations. The nature and severity of the disease was controlled by applying specific strain to the chordae. In this study, in addition to a healthy condition, two different severities of MR were investigated: moderate MR and severe MR. Planar time-resolved particle image velocimetry measurements were performed in order to evaluate the velocity field in the LV and the VED induced by each condition.

RESULTS: Our results showed that MR led to flow disturbances in the LV that were characterized by an increase in mitral inflow velocity and by elevated values of VED. Interestingly VED increased in proportion to the severity of MR and with a dissipation predominating during systole.

CONCLUSION: Considering these results, the introduction of new parameters based on LV VED could provide crucial information regarding the coupling between the mitral valve and the LV and allow for a better stratification of patients with MR.

PMID: 33000444 [PubMed - as supplied by publisher]




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