Keyword search (4,163 papers available)

"Iordanova MD" Authored Publications:

Title Authors PubMed ID
1 Different behavioral measures of conditioned magazine activity can tell different stories about brain function Volz S; Loewinger G; Marquez I; Fevola S; Kang M; Reverte I; Krishnan A; Gardner MPH; Iordanova MD; Esber GR; 41922165
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2 Reduction in reward-driven behaviour depends on the basolateral but not central nucleus of the amygdala in female rats Lay BPP; Esber GR; Iordanova MD; 40925675
PSYCHOLOGY
3 Disentangling prediction error and value in a formal test of dopamine s role in reinforcement learning Usypchuk AA; Maes EJP; Lozzi M; Avramidis DK; Schoenbaum G; Esber GR; Gardner MPH; Iordanova MD; 40738112
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4 The Rescorla-Wagner Model: It Is Not What You Think It Is Esber G; Schoenbaum G; Iordanova MD; 39805526
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5 OFC neurons do not represent the negative value of a conditioned inhibitor Esber GR; Usypchuk A; Saini S; Deroche M; Iordanova MD; Schoenbaum G; 38042330
CONCORDIA
6 Parvalbumin interneuron loss mediates repeated anesthesia-induced memory deficits in mice Roque PS; Thörn Perez C; Hooshmandi M; Wong C; Eslamizade MJ; Heshmati S; Brown N; Sharma V; Lister KC; Goyon VM; Neagu-Lund L; Shen C; Daccache N; Sato H; Sato T; Mogil JS; Nader K; Gkogkas CG; Iordanova MD; Prager-Khoutorsky M; McBride HM; Lacaille JC; Wykes L; Schricker T; Khoutorsky A; 36394958
PSYCHOLOGY
7 The Recruitment of a Neuronal Ensemble in the Central Nucleus of the Amygdala During the First Extinction Episode Has Persistent Effects on Extinction Expression Lay BPP; Koya E; Hope BT; Esber GR; Iordanova MD; 36336498
PSYCHOLOGY
8 Correction to: Persistent disruption of overexpectation learning after inactivation of the lateral orbitofrontal cortex in male rats Lay BPP; Choudhury R; Esber GR; Iordanova MD; 36006415
PSYCHOLOGY
9 Experimental chambers Persistent disruption of overexpectation learning after inactivation of the lateral orbitofrontal cortex in male rats Lay BPP; Choudhury R; Esber GR; Iordanova MD; 35932299
PSYCHOLOGY
10 Understanding Associative Learning Through Higher-Order Conditioning Gostolupce D; Lay BPP; Maes EJP; Iordanova MD; 35517574
PSYCHOLOGY
11 Agency rescues competition for credit assignment among predictive cues from adverse learning conditions Kang M; Reverte I; Volz S; Kaufman K; Fevola S; Matarazzo A; Alhazmi FH; Marquez I; Iordanova MD; Esber GR; 34376741
PSYCHOLOGY
12 Mechanisms of higher-order learning in the amygdala Gostolupce D; Iordanova MD; Lay BPP; 34197867
PSYCHOLOGY
13 Threat perception: Fear and the retrorubal field Bradfield LA; Iordanova MD; 34033766
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14 Neural substrates of appetitive and aversive prediction error. Iordanova MD, Yau JO, McDannald MA, Corbit LH 33453307
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15 Adaptive behaviour under conflict: deconstructing extinction, reversal, and active avoidance learning. Manning EE, Bradfield LA, Iordanova MD 33035525
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16 Different methods of fear reduction are supported by distinct cortical substrates. Lay BP, Pitaru AA, Boulianne N, Esber GR, Iordanova MD 32589138
PSYCHOLOGY
17 A self-initiated cue-reward learning procedure for neural recording in rodents. Reverte I, Volz S, Alhazmi FH, Kang M, Kaufman K, Chan S, Jou C, Iordanova MD, Esber GR 32135212
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18 Causal evidence supporting the proposal that dopamine transients function as temporal difference prediction errors. Maes EJP, Sharpe MJ, Usypchuk AA, Lozzi M, Chang CY, Gardner MPH, Schoenbaum G, Iordanova MD 31959935
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19 Neural correlates of two different types of extinction learning in the amygdala central nucleus. Iordanova MD, Deroche ML, Esber GR, Schoenbaum G 27531638
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20 Dopamine Signaling Is Critical for Supporting Cue-Driven Behavioral Control. Iordanova MD 31103706
PSYCHOLOGY
21 Thought control with the dopamine transient. Iordanova MD 30338459
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22 Dissociation of Appetitive Overexpectation and Extinction in the Infralimic Cortex. Lay BPP, Nicolosi M, Usypchuk AA, Esber GR, Iordanova MD 30371757
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23 Corrigendum: Dissociation of Appetitive Overexpectation and Extinction in the Infralimbic Cortex. Lay BPP, Nicolosi M, Usypchuk AA, Esber GR, Iordanova MD 30590441
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24 The serial blocking effect: a testbed for the neural mechanisms of temporal-difference learning. Mahmud A; Petrov P; Esber GR; Iordanova MD; 30979910
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Title:Different methods of fear reduction are supported by distinct cortical substrates.
Authors:Lay BP,  Pitaru AA,  Boulianne N,  Esber GR,  Iordanova MD
Link:https://www.ncbi.nlm.nih.gov/pubmed/32589138?dopt=Abstract
DOI:10.7554/eLife.55294
Publication:eLife
Keywords:extinction;  fear;  infralimbic;  learning;  neuroscience;  orbitofrontal;  rat; 
PMID:32589138 Category:Elife Date Added:2020-06-27
Dept Affiliation: PSYCHOLOGY
1 Center for Studies in Behavioural Neurobiology, Department of Psychology, Concordia University, Montreal, Canada.
2 Department of Psychology, Brooklyn College of the City University of New York, Brooklyn, United States.

Description:

Different methods of fear reduction are supported by distinct cortical substrates.

Elife. 2020 Jun 26;9:

Authors: Lay BP, Pitaru AA, Boulianne N, Esber GR, Iordanova MD

Abstract

Understanding how learned fear can be reduced is at the heart of treatments for anxiety disorders. Tremendous progress has been made in this regard through extinction training in which the aversive outcome is omitted. However, current progress almost entirely rests on this single paradigm, resulting in a very specialized knowledgebase at the behavioural and neural level of analysis. Here, we used a dual-paradigm approach to show that different methods that lead to reduction in learned fear in rats are dissociated in the cortex. We report that the infralimbic cortex has a very specific role in fear reduction that depends on the omission of aversive events but not on overexpectation. The orbitofrontal cortex, a structure generally overlooked in fear, is critical for downregulating fear when novel predictions about upcoming aversive events are generated, such as when fear is inflated or overexpected, but less so when an expected aversive event is omitted.

PMID: 32589138 [PubMed - as supplied by publisher]




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