Keyword search (4,163 papers available)

"Fan AP" Authored Publications:

Title Authors PubMed ID
1 Modeling venous bias in resting state functional MRI metrics Huck J; Jäger AT; Schneider U; Grahl S; Fan AP; Tardif C; Villringer A; Bazin PL; Steele CJ; Gauthier CJ; 37498014
PERFORM
2 BOLD signal physiology: Models and applications. Gauthier CJ, Fan AP 29544818
IMAGING
3 High resolution atlas of the venous brain vasculature from 7 T quantitative susceptibility maps. Huck J, Wanner Y, Fan AP, Jäger AT, Grahl S, Schneider U, Villringer A, Steele CJ, Tardif CL, Bazin PL, Gauthier CJ 31278570
PSYCHOLOGY
4 Elevated brain oxygen extraction fraction measured by MRI susceptibility relates to perfusion status in acute ischemic stroke. Fan AP, Khalil AA, Fiebach JB, Zaharchuk G, Villringer A, Villringer K, Gauthier CJ 30732551
PHYSICS

 

Title:BOLD signal physiology: Models and applications.
Authors:Gauthier CJFan AP
Link:https://www.ncbi.nlm.nih.gov/pubmed/29544818?dopt=Abstract
DOI:10.1016/j.neuroimage.2018.03.018
Publication:NeuroImage
Keywords:
PMID:29544818 Category:Neuroimage Date Added:2019-08-07
Dept Affiliation: IMAGING
1 Concordia University, Montreal, Canada. Electronic address: claudine.gauthier@concordia.ca.
2 Stanford University, California, USA.

Description:

BOLD signal physiology: Models and applications.

Neuroimage. 2019 02 15;187:116-127

Authors: Gauthier CJ, Fan AP

Abstract

The BOLD contrast mechanism has a complex relationship with functional brain activity, oxygen metabolism, and neurovascular factors. Accurate interpretation of the BOLD signal for neuroscience and clinical applications necessitates a clear understanding of the sources of BOLD contrast and its relationship to underlying physiology. This review describes the physiological components that contribute to the BOLD signal and the steady-state calibrated BOLD models that enable quantification of functional changes with a separate challenge paradigm. The principles derived from these biophysical models are then used to interpret BOLD measurements in different neurological disorders in the presence of confounding vascular factors related to disease.

PMID: 29544818 [PubMed - indexed for MEDLINE]





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