Keyword search (4,163 papers available)

"Einstein G" Authored Publications:

Title Authors PubMed ID
1 Biological sex and bilingualism: Its impact on risk and resilience for dementia Calvo N; Phillips N; Bialystok E; Einstein G; 41573422
PSYCHOLOGY
2 Use of lecanemab and donanemab in the Canadian healthcare system: Evidence, challenges, and areas for future research Smith EE; Phillips NA; Feldman HH; Borrie M; Ganesh A; Henri-Bhargava A; Desmarais P; Frank A; Badhwar A; Barlow L; Bartha R; Best S; Bethell J; Bhangu J; Black SE; Bocti C; Bronskill SE; Burhan AM; Calon F; Camicioli R; Campbell B; Collins DL; Dadar M; DeMarco ML; Ducharme S; Duchesne S; Einstein G; Fisk JD; Gawryluk JR; Grossman L; Ismail Z; Itzhak I; Joshi M; Harrison A; Kroger E; Kumar S; Laforce R; Lanctot KL; Lau M; Lee L; Masellis M; Massoud F; Mitchell SB; Montero-Odasso M; Myers Barnett K; Nygaard HB; Pasternak SH; Peters J; Rajah MN; Robillard JM; Rockwood K; Rosa-Neto P; Seitz DP; Soucy JP; Trenaman SC; Wellington CL; Zadem A; Chertkow H; 39893139
CONCORDIA
3 Clinical Manifestations Calvo N; Siddiqui R; Phillips N; Einstein G; 39750698
CONCORDIA
4 Impact of a national dementia research consortium: The Canadian Consortium on Neurodegeneration in Aging (CCNA) Chertkow H; Phillips N; Rockwood K; Anderson N; Andrew MK; Bartha R; Beaudoin C; Bélanger N; Bellec P; Belleville S; Bergman H; Best S; Bethell J; Bherer L; Black S; Borrie M; Camicioli R; Carrier J; Cashman N; Chan S; Crowshoe L; Cuello C; Cynader M; Dang-Vu T; Das S; Dixon RA; Ducharme S; Einstein G; Evans AC; Fahnestock M; Feldman H; Ferland G; Finger E; Fisk JD; Fogarty J; Fon E; Gan-Or Z; Gauthier S; Greenwood C; Henri-Bellemare C; Herrmann N; Hogan DB; Hsiung R; Itzhak I; Jacklin K; Lanctôt K; Lim A; MacKenzie I; Masellis M; Maxwell C; McAiney C; McGilton K; McLaurin J; Mihailidis A; Mohades Z; Montero-Odasso M; Morgan D; Naglie G; Nygaard H; O' Connell M; Petersen R; Pilon R; Rajah MN; Rapoport M; Roach P; Robillard JM; Rogaeva E; Rosa-Neto P; Rylett J; Sadavoy J; St George-Hyslop P; Seitz D; Smith E; Stefanovic B; Vedel I; Walker JD; Wellington C; Whitehead V; Wittich W; 39636028
HKAP
5 Effects of early midlife ovarian removal on sleep: Polysomnography-measured cortical arousal, homeostatic drive, and spindle characteristics Brown A; Gervais NJ; Gravelsins L; O' Byrne J; Calvo N; Ramana S; Shao Z; Bernardini M; Jacobson M; Rajah MN; Einstein G; 39178647
HKAP
6 A portrait of obstructive sleep apnea risk factors in 27,210 middle-aged and older adults in the Canadian Longitudinal Study on Aging Thompson C; Legault J; Moullec G; Baltzan M; Cross N; Dang-Vu TT; Martineau-Dussault MÈ; Hanly P; Ayas N; Lorrain D; Einstein G; Carrier J; Gosselin N; 35332170
PERFORM

 

Title:Biological sex and bilingualism: Its impact on risk and resilience for dementia
Authors:Calvo NPhillips NBialystok EEinstein G
Link:https://pubmed.ncbi.nlm.nih.gov/41573422/
DOI:10.1002/dad2.70255
Publication:Alzheimer s & dementia (Amsterdam, Netherlands)
Keywords:GFAPNfLbilingualismmild cognitive impairmentp‐tau181risk and resiliencesex differences
PMID:41573422 Category: Date Added:2026-01-23
Dept Affiliation: PSYCHOLOGY
1 Department of Psychology University of Toronto Toronto Ontario Canada.
2 Department of Psychology Concordia University Montreal Quebec Canada.
3 Department of Psychology York University Toronto Ontario Canada.
4 Tema Genus Linkoping University Linkoping Sweden.
5 Rotman Research Institute Baycrest Hospital Toronto Ontario Canada.
6 Dalla Lana School of Public Health University of Toronto Toronto Ontario Canada.

Description:

Introduction: The relationship between biological sex, considered a risk factor for Alzheimer's disease (AD), and bilingualism, a resilience factor, is unclear. We assessed this relationship in 335 individuals with mild cognitive impairment (MCI) in a Canadian cohort.

Methods: We used univariate analysis and structural equation modelling to study the relationship between female sex and bilingualism. We created a resilience index (RI) for each participant using the residual approach. Logistic and linear regressions predicted cognitive and brain health in relation to RI.

Results: Overall, bilingual males had increased RI. Higher RI was associated with less risk of AD and less neuropathology and glial activation as indexed by plasma p-tau181, neurofilament light, and glial fibrillary acidic protein.

Discussion: In MCI, the combination of elevated estradiol levels due to aromatization and bilingualism may provide synergistic protection for verbal memory, making old bilingual males more resilient.

Highlights: Sex steroids influence verbal memoryIn a structural equation modeling (SEM) model, verbal memory mediates cognitive declineElevated estradiol from aromatization makes old bilinguals more resilient.





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