Keyword search (4,164 papers available)

"Darlington PJ" Authored Publications:

Title Authors PubMed ID
1 Nicotine Suppresses Human Memory Th Cell Subsets With Preferential Effects on Central Memory Th Cells in an α7 Nicotinic Acetylcholine Receptor-Dependent Manner Gholizadeh F; Hajiaghayi M; Rahbari N; Choi JS; Heidt S; Como A; Kazerouni M; Kargar M; Pinard-LaRoche A; Shih SCC; Darlington PJ; 41928597
SOH
2 Nebivolol prevents exhausted T cells and enhances cytotoxicity against MCF-7 breast cancer cells in a β2-adrenergic receptor-dependent manner Hajiaghayi M; Gholizadeh F; Rahbari N; Emamnia N; Shih SCC; Darlington PJ; 41906691
SOH
3 Modulatory effects of M3 muscarinic acetylcholine receptor on inflammatory profiles of human memory T helper cells Gholizadeh F; Hajiaghayi M; Choi JS; Little SR; Rahbari N; Kargar M; Brotto K; Han E; Shih SCC; Darlington PJ; 40405417
BIOLOGY
4 A Digital Microfluidic Platform for the Microscale Production of Functional Immune Cell Therapies Little SR; Rahbari N; Hajiaghayi M; Gholizadeh F; Cloarec-Ung FM; Phillips J; Sinha H; Hirukawa A; Knapp DJHF; Darlington PJ; Shih SCC; 40390294
BIOLOGY
5 Immunomodulation of human T cells by microbubble-mediated focused ultrasound Baez A; Singh D; He S; Hajiaghayi M; Gholizadeh F; Darlington PJ; Helfield B; 39502696
BIOLOGY
6 The β2-adrenergic biased agonist nebivolol inhibits the development of Th17 and the response of memory Th17 cells in an NF-κB-dependent manner Hajiaghayi M; Gholizadeh F; Han E; Little SR; Rahbari N; Ardila I; Lopez Naranjo C; Tehranimeh K; Shih SCC; Darlington PJ; 39445009
BIOLOGY
7 The β2-adrenergic receptor agonist terbutaline upregulates T helper-17 cells in a protein kinase A-dependent manner Carvajal Gonczi CM; Hajiaghayi M; Gholizadeh F; Xavier Soares MA; Touma F; Lopez Naranjo C; Rios AJ; Pozzebon C; Daigneault T; Burchell-Reyes K; Darlington PJ; 37438188
PERFORM
8 Genetic Screening of Candida albicans Inactivation Mutants Identifies New Genes Involved in Macrophage-Fungal Cell Interactions Godoy P; Darlington PJ; Whiteway M; 35450285
PERFORM
9 Elevated Heart Rate and Pain During a Cold Pressor Test Correlates to Pain Catastrophizing Kakon G; Mohamadi AK; Levtova N; Maurice-Ventouris MEI; Benoit EA; Chouchou F; Darlington PJ; Dover G; 34453652
PERFORM
10 Association Between Pain Catastrophizing and Pain and Cardiovascular Changes During a Cold-Pressor Test in Athletes Lentini M; Scalia J; Lebel FB; Touma F; Jhajj A; Darlington PJ; Dover G; 34000018
PERFORM
11 Pain catastrophizing in athletes correlates with pain and cardiovascular changes during a painful cold pressor test Matylda L; Joseph S; Frédérike BL; Fadi T; Aneet J; Darlington PJ; Dover G; 33150380
PERFORM
12 Human Mesenchymal Stem Cells Impact Th17 and Th1 Responses Through a Prostaglandin E2 and Myeloid-Dependent Mechanism. Rozenberg A, Rezk A, Boivin MN, Darlington PJ, Nyirenda M, Li R, Jalili F, Winer R, Artsy EA, Uccelli A, Reese JS, Planchon SM, Cohen JA, Bar-Or A 27400792
HKAP
13 Comparative morphology and phagocytic capacity of primary human adult microglia with time-lapse imaging. Levtova N, Healy LM, Gonczi CMC, Stopnicki B, Blain M, Kennedy TE, Moore CS, Antel JP, Darlington PJ 28606377
PERFORM
14 Detecting glycogen in peripheral blood mononuclear cells with periodic acid schiff staining. Tabatabaei Shafiei M, Carvajal Gonczi CM, Rahman MS, East A, François J, Darlington PJ 25548935
PERFORM
15 Reciprocal modulation of helper Th1 and Th17 cells by the β2-adrenergic receptor agonist drug terbutaline. Carvajal Gonczi CM, Tabatabaei Shafiei M, East A, Martire E, Maurice-Ventouris MHI, Darlington PJ 28710773
PERFORM
16 Natural Killer Cells Regulate Th17 Cells After Autologous Hematopoietic Stem Cell Transplantation for Relapsing Remitting Multiple Sclerosis. Darlington PJ, Stopnicki B, Touil T, Doucet JS, Fawaz L, Roberts ME, Boivin MN, Arbour N, Freedman MS, Atkins HL, Bar-Or A 29867923
PERFORM
17 Helper CD4 T cells expressing granzyme B cause glial fibrillary acidic protein fragmentation in astrocytes in an MHCII-independent manner. Stopnicki B, Blain M, Cui QL, Kennedy TE, Antel JP, Healy LM, Darlington PJ 30444064
PERFORM

 

Title:Pain catastrophizing in athletes correlates with pain and cardiovascular changes during a painful cold pressor test
Authors:Matylda LJoseph SFrédérike BLFadi TAneet JDarlington PJDover G
Link:https://pubmed.ncbi.nlm.nih.gov/33150380/
DOI:10.4085/16-20
Publication:Journal of athletic training
Keywords:Pain related fearblood pressureheart ratesport
PMID:33150380 Category: Date Added:2020-11-05
Dept Affiliation: PERFORM
1 1 Concordia University, PERFORM Centre, Department of Health, Kinesiology, and Applied Physiology, Loyola Campus SP165.41 - 7141 Sherbrooke Street W. Montreal, Quebec, Canada H4B 1R6.
2 2 Centre de recherche interdisciplinaire en réadaptation du Montréal Métropolitain, Constance Lethbridge centre, CIUSSS du Centre-Ouest-de-l'Île-de-Montréal, 7005 boul. de Maisonneuve Ouest, Montréal QC H4B 1T3.

Description:

Context: Athletes are often exposed to pain due to injury and competition. There is preliminary evidence that cardiovascular measures could be an objective measure of pain, but the cardiovascular response can be influenced by psychological factors such as catastrophizing.

Objectives: The purpose of our study was to use a painful cold pressor test to measure the relationship between catastrophizing, pain, and cardiovascular variables in athletes.

Design: Pre-post test.

Setting: We completed all measures in a laboratory setting.

Participants: Thirty-six male rugby athletes participated in the study.

Main outcome measures: We measured catastrophizing with the Pain Catastrophizing Scale and pain with a Numeric Pain Rating Scale. Cardiovascular measures included heart rate, systolic, and diastolic blood pressure, and heart rate variability.

Results: During the cold pressor test, participants experienced a significant increase in pain (0 to 4.1±2.2), systolic blood pressure (126.7±16.5mm Hg to 149.7±23.4mm Hg), diastolic blood pressure (76.9±8.3mm Hg to 91.9±11.5mm Hg) and heart rate variability (from 0.0164ms±0.0121 to 0.0400ms±0.0323) (all p<.001). In addition, there was a significant decrease in heart rate after the cold pressor test (p=0.04). There was a significant correlation between athlete's pain catastrophizing to both pain intensity and change in heart rate during the cold pressor test (p=.017 and p=.003 respectively). A significant linear regression indicated pain and catastrophizing explained 29% of the variance of the change in heart rate (p=.003).

Conclusion: Athletes who have catastrophizing thoughts are more likely to experience higher levels of pain and a greater cardiovascular response during a painful stimulus. The change in cardiovascular variables may be a good alternative for an objective measure of pain in athletes in the future.





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