Keyword search (4,164 papers available)

"Cruz-Santiago D" Authored Publications:

Title Authors PubMed ID
1 Neuropsychiatric Symptoms and Psychotropic Medication Use Following SARS-Cov-2 Infection Among Elderly Residents in Long-Term Care Facilities Cruz-Santiago D; Meng X; Canac-Marquis M; Sengupta A; Brassard JP; Pavey E; Girouard H; Vinh DC; Gouin JP; 40051588
PSYCHOLOGY
2 Real-world serological responses to extended-interval and heterologous COVID-19 mRNA vaccination in frail, older people (UNCoVER): an interim report from a prospective observational cohort study Vinh DC; Gouin JP; Cruz-Santiago D; Canac-Marquis M; Bernier S; Bobeuf F; Sengupta A; Brassard JP; Guerra A; Dziarmaga R; Perez A; Sun Y; Li Y; Roussel L; Langelier MJ; Ke D; Arnold C; Whelan M; Pelchat M; Langlois MA; Zhang X; Mazer BD; 35224524
PSYCHOLOGY
3 The Association between Generalized Anxiety Disorder, Subthreshold Anxiety Symptoms and Fear of Falling among Older Adults: Preliminary Results from a Pilot Study. Payette MC, Bélanger C, Benyebdri F, Filiatrault J, Bherer L, Bertrand JA, Nadeau A, Bruneau MA, Clerc D, Saint-Martin M, Cruz-Santiago D, Ménard C, Nguyen P, Vu TTM, Comte F, Bobeuf F, Grenier S 28452660
PERFORM

 

Title:Neuropsychiatric Symptoms and Psychotropic Medication Use Following SARS-Cov-2 Infection Among Elderly Residents in Long-Term Care Facilities
Authors:Cruz-Santiago DMeng XCanac-Marquis MSengupta ABrassard JPPavey EGirouard HVinh DCGouin JP
Link:https://pubmed.ncbi.nlm.nih.gov/40051588/
DOI:10.5770/cgj.28.770
Publication:Canadian geriatrics journal : CGJ
Keywords:COVID-19dementianeuropsychiatric symptomsnursing homesolder adults
PMID:40051588 Category: Date Added:2025-03-07
Dept Affiliation: PSYCHOLOGY
1 Montreal Geriatrics Institute Research Centre, Montreal.
2 Department of Family and Emergency Medicine, University of Montreal, Montreal.
3 Department of Psychiatry, Faculty of Medicine and Health Sciences, McGill University, Montreal.
4 Douglas Research Center, Montreal.
5 Research Institute of the McGill University Health Centre, Montreal.
6 Department of Pharmacology and Physiology, University of Montreal, Montreal.
7 Infectious Diseases and Immunity in Global Health Program, Montreal.
8 Division of Infectious Diseases, Department of Medicine, McGill University Health Centre, Montréal.
9 Department of Psychology, Concordia University, Montreal, QC.

Description:

Background: SARS-CoV-2 infection can lead to persistent post-acute neuropsychiatric symptoms. Older adults with multimorbidity may be at increased risk of post-acute symptoms after COVID-19. The goals of the present study were to assess the associations of SARS-CoV-2 infection with neuropsychiatric symptoms and psychotropic medication prescription among older adults living in long-term care facilities.

Methods: Nursing home residents (n=111) participated in this three-month longitudinal study. Nurse ratings of neuropsychiatric symptoms were conducted at baseline and at the three-month follow-up. SARS-CoV-2 infection status and psychotropic medication prescription were extracted from a medical chart review.

Results: About 73.9% of participants were infected with SARS-CoV-2 on average 480.49 (SD= 228) days before study enrollment. There were no significant changes in neuropsychiatric symptoms during the study follow-up period. Participants with a SARS-CoV-2 infection had more agitation compared to those who were never infected. However, this effect disappeared after adjusting for age, sex, history of psychiatric disorder, neurocognitive status, and multimorbidity. Participants with SARS-CoV-2 had a higher number of psychotropic medication prescription. This effect was driven by increased use of antidepressants and antipsychotic medications.

Conclusion: Both acute and short-term neuropsychiatric symptoms associated with COVID-19 may contribute to long-term psychoactive polypharmacy among older adults living in long-term facilities.





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