Keyword search (4,163 papers available)

"Chaudhri N" Authored Publications:

Title Authors PubMed ID
1 Augmenting glutamatergic, but not dopaminergic, activity in the nucleus accumbens shell disrupts responding to a discrete alcohol cue in an alcohol context Valyear MD; Brown A; Deyab G; Villaruel FR; Lahlou S; Caporicci-Dinucci N; Chaudhri N; 38185906
PSYCHOLOGY
2 Neural correlates of recall and extinction in a rat model of appetitive Pavlovian conditioning Brown A; Villaruel FR; Chaudhri N; 36496079
PSYCHOLOGY
3 Optogenetic stimulation of infralimbic cortex projections to the paraventricular thalamus attenuates context-induced renewal Brown A; Chaudhri N; 36373226
PSYCHOLOGY
4 Learning processes in relapse to alcohol use: lessons from animal models Valyear MD; LeCocq MR; Brown A; Villaruel FR; Segal D; Chaudhri N; 36264342
PSYCHOLOGY
5 Supplementary dataset of context-dependent conditioned responding to an alcohol-predictive cue in female and male rats Segal D; Valyear MD; Chaudhri N; 35330738
PSYCHOLOGY
6 Corticostriatal suppression of appetitive Pavlovian conditioned responding Villaruel FR; Martins M; Chaudhri N; 34880119
PSYCHOLOGY
7 The Role of Context Conditioning in the Reinstatement of Responding to an Alcohol-Predictive Conditioned Stimulus LeCocq MR; Sun S; Chaudhri N; 34852244
PSYCHOLOGY
8 The role of context on responding to an alcohol-predictive cue in female and male rats Segal D; Valyear MD; Chaudhri N; 34742865
PSYCHOLOGY
9 Cue-alcohol associative learning in female rats. Cofresí RU, Monfils MH, Chaudhri N, Gonzales RA, Lee HJ 31002878
PSYCHOLOGY
10 Dissociable mesolimbic dopamine circuits control responding triggered by alcohol-predictive discrete cues and contexts. Valyear MD, Glovaci I, Zaari A, Lahlou S, Trujillo-Pisanty I, Andrew Chapman C, Chaudhri N 32724058
PSYCHOLOGY
11 Comparing ABA, AAB, and ABC Renewal of Appetitive Pavlovian Conditioned Responding in Alcohol- and Sucrose-Trained Male Rats. Khoo SY, Sciascia JM, Brown A, Chaudhri N 32116588
PSYCHOLOGY
12 Context controls the timing of responses to an alcohol-predictive conditioned stimulus. Valyear MD, Chaudhri N 32017964
PSYCHOLOGY
13 Considering Drug-Associated Contexts in Substance Use Disorders and Treatment Development. LeCocq MR, Randall PA, Besheer J, Chaudhri N 31898285
CSBN
14 Alcohol-associated antecedent stimuli elicit alcohol seeking in non-dependent rats and may activate the insula. Cofresí RU, Grote DJ, Le EVT, Monfils MH, Chaudhri N, Gonzales RA, Lee HJ 30612041
PSYCHOLOGY
15 The medial prefrontal cortex is required for responding to alcohol-predictive cues but only in the absence of alcohol delivery. Khoo SY, Sciascia JM, Pettorelli A, Maddux JN, Chaudhri N 31070082
PSYCHOLOGY
16 Vendor differences in alcohol consumption and the contribution of dopamine receptors to Pavlovian-conditioned alcohol-seeking in Long-Evans rats. Sparks LM, Sciascia JM, Ayorech Z, Chaudhri N 24096535
PSYCHOLOGY
17 The attribution of incentive salience to Pavlovian alcohol cues: a shift from goal-tracking to sign-tracking. Srey CS, Maddux JM, Chaudhri N 25784867
CSBN
18 Alcohol-Seeking Triggered by Discrete Pavlovian Cues is Invigorated by Alcohol Contexts and Mediated by Glutamate Signaling in the Basolateral Amygdala. Sciascia JM, Reese RM, Janak PH, Chaudhri N 25953360
PSYCHOLOGY
19 Robust optical fiber patch-cords for in vivo optogenetic experiments in rats. Trujillo-Pisanty I, Sanio C, Chaudhri N, Shizgal P 26150997
CSBN
20 Varenicline Reduces Context-Induced Relapse to Alcohol-Seeking through Actions in the Nucleus Accumbens. Lacroix F, Pettorelli A, Maddux JN, Heidari-Jam A, Chaudhri N 27834390
PSYCHOLOGY
21 Nicotine-induced enhancement of Pavlovian alcohol-seeking behavior in rats. Maddux JN, Chaudhri N 28011981
CSBN
22 Individual Differences in the Attribution of Incentive Salience to a Pavlovian Alcohol Cue. Villaruel FR, Chaudhri N 28082877
PSYCHOLOGY
23 Postretrieval Extinction Attenuates Alcohol Cue Reactivity in Rats. Cofresí RU, Lewis SM, Chaudhri N, Lee HJ, Monfils MH, Gonzales RA 28169439
CSBN
24 Alcohol-seeking and relapse: A focus on incentive salience and contextual conditioning. Valyear MD, Villaruel FR, Chaudhri N 28473252
PSYCHOLOGY
25 Optogenetic Activation of the Infralimbic Cortex Suppresses the Return of Appetitive Pavlovian-Conditioned Responding Following Extinction. Villaruel FR, Lacroix F, Sanio C, Sparks DW, Chapman CA, Chaudhri N 29045570
PSYCHOLOGY
26 Characterizing conditioned reactivity to sequential alcohol-predictive cues in well-trained rats. Cofresí RU, Lee HJ, Monfils MH, Chaudhri N, Gonzales RA 29635111
PSYCHOLOGY
27 Modeling Relapse to Pavlovian Alcohol-Seeking in Rats Using Reinstatement and Spontaneous Recovery Paradigms. LeCocq MR, Lahlou S, Chahine M, Padillo LN, Chaudhri N 29969151
CSBN
28 Context and topography determine the role of basolateral amygdala metabotropic glutamate receptor 5 in appetitive Pavlovian responding. Khoo SY, LeCocq MR, Deyab GE, Chaudhri N 30758331
PSYCHOLOGY

 

Title:Alcohol-associated antecedent stimuli elicit alcohol seeking in non-dependent rats and may activate the insula.
Authors:Cofresí RU,  Grote DJ,  Le EVT,  Monfils MH,  Chaudhri N,  Gonzales RA,  Lee HJ
Link:https://www.ncbi.nlm.nih.gov/pubmed/30612041?dopt=Abstract
Publication:
Keywords:
PMID:30612041 Category:Alcohol Date Added:2019-06-03
Dept Affiliation: PSYCHOLOGY
1 The University of Texas at Austin, Austin, TX, United States; Institute for Neuroscience, The University of Texas at Austin, Austin, TX, United States.
2 The University of Texas at Austin, Austin, TX, United States.
3 The University of Texas at Austin, Austin, TX, United States; Institute for Neuroscience, The University of Texas at Austin, Austin, TX, United States; Department of Psychology, The University of Texas at Austin, Austin, TX, United States.
4 Concordia University, Montreal, Quebec, Canada; Center for Studies in Behavioral Neurobiology, Concordia University, Montreal, Quebec, Canada.
5 The University of Texas at Austin, Austin, TX, United States; Institute for Neuroscience, The University of Texas at Austin, Austin, TX, United States; Division of Pharmacology & Toxicology, The University of Texas at Austin, Austin, TX, United States.
6 The University of Texas at Austin, Austin, TX, United States; Institute for Neuroscience, The University of Texas at Austin, Austin, TX, United States; Department of Psychology, The University of Texas at Austin, Austin, TX, United States. Electronic address: leehj@austin.utexas.edu.

Description:

Alcohol-associated antecedent stimuli elicit alcohol seeking in non-dependent rats and may activate the insula.

Alcohol. 2019 May;76:91-102

Authors: Cofresí RU, Grote DJ, Le EVT, Monfils MH, Chaudhri N, Gonzales RA, Lee HJ

Abstract

Alcohol self-administration produces brain and behavior adaptations that facilitate a progressive loss of control over drinking and contribute to relapse. One possible adaptation is the ability of antecedent environmental stimuli that are consistently paired with alcohol to trigger alcohol-seeking behaviors. We previously modeled this adaptation in rats using a Pavlovian conditioning procedure in which illumination of a houselight preceded the presentation of a sipper tube that produced unsweetened alcohol when licked. However, in our previous work we did not demonstrate whether this adaptation represented a consequence of repeated exposure to alcohol or the houselight, or whether it was the consequence of associative learning and memory. Thus, in the present study, we tested the associative basis of alcohol seeking in response to houselight illumination in our task using adult male rats that were not food- or water-deprived and were not dependent on alcohol. Separate groups of rats received houselight illumination that was explicitly paired or unpaired with presentation of the retractable sipper that provided access to unsweetened alcohol. Our primary dependent variable was appetitive alcohol-directed behavior: the frequency of movement toward and interaction with the hole in the wall of the chamber through which the sipper was presented during the period of houselight illumination trial before each sipper presentation. However, we also analyzed consummatory sipper licking behavior and blood ethanol concentration in the same rats. Finally, we explored the brain basis of cue-elicited alcohol seeking using c-Fos immunohistochemistry. Our findings confirmed the associative basis of cue-elicited alcohol seeking in our paradigm and mapped these onto the insular cortex, suggesting a role for this brain region in early stages of brain and behavior adaptation to regular alcohol use.

PMID: 30612041 [PubMed - in process]




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