BookR: School of Health Core Facilities Booking
PubMed Publications| Keyword search (4,163 papers available) |  |
"Bialystok E" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Biological sex and bilingualism: Its impact on risk and resilience for dementia | Calvo N; Phillips N; Bialystok E; Einstein G; | 41573422 PSYCHOLOGY |
| 2 | The effects of bilingualism on toddlers' executive functioning. | Poulin-Dubois D, Blaye A, Coutya J, Bialystok E | 21122877 CRDH |
| Title: | Biological sex and bilingualism: Its impact on risk and resilience for dementia | ||||
| Authors: | Calvo N, Phillips N, Bialystok E, Einstein G | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/41573422/ | ||||
| DOI: | 10.1002/dad2.70255 | ||||
| Publication: | Alzheimer s & dementia (Amsterdam, Netherlands) | ||||
| Keywords: | GFAP; NfL; bilingualism; mild cognitive impairment; p‐; tau181; risk and resilience; sex differences; | ||||
| PMID: | 41573422 | Category: | Date Added: | 2026-01-23 | |
| Dept Affiliation: |
PSYCHOLOGY
1 Department of Psychology University of Toronto Toronto Ontario Canada. 2 Department of Psychology Concordia University Montreal Quebec Canada. 3 Department of Psychology York University Toronto Ontario Canada. 4 Tema Genus Linkoping University Linkoping Sweden. 5 Rotman Research Institute Baycrest Hospital Toronto Ontario Canada. 6 Dalla Lana School of Public Health University of Toronto Toronto Ontario Canada. |
||||
Description: |
Introduction: The relationship between biological sex, considered a risk factor for Alzheimer's disease (AD), and bilingualism, a resilience factor, is unclear. We assessed this relationship in 335 individuals with mild cognitive impairment (MCI) in a Canadian cohort. Methods: We used univariate analysis and structural equation modelling to study the relationship between female sex and bilingualism. We created a resilience index (RI) for each participant using the residual approach. Logistic and linear regressions predicted cognitive and brain health in relation to RI. Results: Overall, bilingual males had increased RI. Higher RI was associated with less risk of AD and less neuropathology and glial activation as indexed by plasma p-tau181, neurofilament light, and glial fibrillary acidic protein. Discussion: In MCI, the combination of elevated estradiol levels due to aromatization and bilingualism may provide synergistic protection for verbal memory, making old bilingual males more resilient. Highlights: Sex steroids influence verbal memoryIn a structural equation modeling (SEM) model, verbal memory mediates cognitive declineElevated estradiol from aromatization makes old bilinguals more resilient. |
