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PubMed Publications| Keyword search (4,163 papers available) |  |
"Bherer L" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | The effect of hearing ability on dual-task performance following multi-domain training in older adults with mild cognitive impairment: findings from the SYNERGIC trial | Downey RI; Petersen BJ; Mohanathas N; Campos JL; Montero-Odasso M; Bherer L; Pichora-Fuller MK; Bray NW; Burhan AM; Camicioli R; Fraser S; Liu-Ambrose T; Lussier M; Middleton LE; Pieruccini-Faria F; Phillips NA; Li KZH; | 41694460 SOH |
| 2 | Cardiorespiratory fitness in relation to cerebral vascular and metabolic health in older adults with coronary artery disease | Sanami S; Tremblay SA; Potvin-Jutras Z; Rezaei A; Sabra D; Gagnon C; Intzandt B; Mainville-Berthiaume A; Wright L; Gayda M; Iglesies-Grau J; Nigam A; Bherer L; Gauthier CJ; | 41680492 SOH |
| 3 | Greater cardiorespiratory fitness is associated with higher cerebral blood flow and lower oxygen extraction fraction in healthy older adults | Sanami S; Rezaei A; Tremblay SA; Potvin-Jutras Z; Sabra D; Intzandt B; Gagnon C; Mainville-Berthiaume A; Wright L; Gayda M; Iglesies-Grau J; Nigam A; Bherer L; Gauthier CJ; | 41543005 SOH |
| 4 | The Impact of Coronary Artery Disease on Brain Vascular and Metabolic Health: Links to Cognitive Function | Sanami S; Tremblay SA; Rezaei A; Potvin-Jutras Z; Sabra D; Intzandt B; Gagnon C; Mainville-Berthiaume A; Wright L; Gayda M; Iglesies-Grau J; Nigam A; Bherer L; Gauthier CJ; | 41452711 SOH |
| 5 | Dementia Care Research and Psychosocial Factors | Mancor E; Montero-Odasso M; Bherer L; Almeida QJ; Liu-Ambrose T; Middleton LE; Camicioli R; Li K; | 41448628 CONCORDIA |
| 6 | Clinical Manifestations | Gagnon C; Montero-Odasso M; Zou G; Speechley MR; Almeida QJ; Liu-Ambrose T; Middleton LE; Camicioli R; Bray NW; Li K; Fraser S; Pieruccini-Faria F; Burhan AM; Berryman N; Lussier M; Son S; Shoemaker JK; Bherer L; | 41447475 CONCORDIA |
| 7 | Public Health | Pieruccini-Faria F; Son S; Liu-Ambrose T; Burhan AM; Almeida QJ; Middleton LE; Li K; Fraser S; Bherer L; Montero-Odasso M; | 41435121 CONCORDIA |
| 8 | Synergistic effects of exercise, cognitive training and vitamin D on gait performance and falls in mild cognitive impairment-secondary outcomes from the SYNERGIC trial | Pieruccini-Faria F; Son S; Zou G; Almeida QJ; Middleton LE; Bray NW; Lussier M; Shoemaker JK; Speechley M; Liu-Ambrose T; Burhan AM; Camicioli R; Li KZH; Fraser S; Berryman N; Bherer L; Montero-Odasso M; | 40966614 SOH |
| 9 | Multivariate white matter microstructure alterations in older adults with coronary artery disease | Tremblay SA; Potvin-Jutras Z; Sabra D; Rezaei A; Sanami S; Gagnon C; Intzandt B; Mainville-Berthiaume A; Wright L; Leppert IR; Tardif CL; Steele CJ; Iglesies-Grau J; Nigam A; Bherer L; Gauthier CJ; | 40829939 SOH |
| 10 | Investigating the effects of a randomized, double-blinded aerobic, resistance, and cognitive training clinical trial on neurocognitive function in older adults with cardiovascular risk factors: the ACTIONcardioRisk protocol | Bherer L; Vrinceanu T; Dupuy EG; Gayda M; Vincent T; Magnan PO; Mohammadi H; Gauthier C; Gagnon C; Duchesne S; Erickson KI; Gagnon D; Lesage F; Lupien S; Poirier J; Dubé MP; Thorin É; Juneau M; Breton J; Belleville S; Ferland G; Gaudreau-Majeau F; Blanchette CA; Vitali P; Nigam A; | 40625372 PSYCHOLOGY |
| 11 | NIRSTORM: a Brainstorm extension dedicated to functional near-infrared spectroscopy data analysis, advanced 3D reconstructions, and optimal probe design | Delaire É; Vincent T; Cai Z; Machado A; Hugueville L; Schwartz D; Tadel F; Cassani R; Bherer L; Lina JM; Pélégrini-Issac M; Grova C; | 40375973 SOH |
| 12 | Impact of a national dementia research consortium: The Canadian Consortium on Neurodegeneration in Aging (CCNA) | Chertkow H; Phillips N; Rockwood K; Anderson N; Andrew MK; Bartha R; Beaudoin C; Bélanger N; Bellec P; Belleville S; Bergman H; Best S; Bethell J; Bherer L; Black S; Borrie M; Camicioli R; Carrier J; Cashman N; Chan S; Crowshoe L; Cuello C; Cynader M; Dang-Vu T; Das S; Dixon RA; Ducharme S; Einstein G; Evans AC; Fahnestock M; Feldman H; Ferland G; Finger E; Fisk JD; Fogarty J; Fon E; Gan-Or Z; Gauthier S; Greenwood C; Henri-Bellemare C; Herrmann N; Hogan DB; Hsiung R; Itzhak I; Jacklin K; Lanctôt K; Lim A; MacKenzie I; Masellis M; Maxwell C; McAiney C; McGilton K; McLaurin J; Mihailidis A; Mohades Z; Montero-Odasso M; Morgan D; Naglie G; Nygaard H; O' Connell M; Petersen R; Pilon R; Rajah MN; Rapoport M; Roach P; Robillard JM; Rogaeva E; Rosa-Neto P; Rylett J; Sadavoy J; St George-Hyslop P; Seitz D; Smith E; Stefanovic B; Vedel I; Walker JD; Wellington C; Whitehead V; Wittich W; | 39636028 HKAP |
| 13 | At-home computerized executive-function training to improve cognition and mobility in normal-hearing adults and older hearing aid users: a multi-centre, single-blinded randomized controlled trial | Downey R; Gagné N; Mohanathas N; Campos JL; Pichora-Fuller KM; Bherer L; Lussier M; Phillips NA; Wittich W; St-Onge N; Gagné JP; Li K; | 37864139 PERFORM |
| 14 | Effects of Exercise Alone or Combined With Cognitive Training and Vitamin D Supplementation to Improve Cognition in Adults With Mild Cognitive Impairment: A Randomized Clinical Trial | Montero-Odasso M; Zou G; Speechley M; Almeida QJ; Liu-Ambrose T; Middleton LE; Camicioli R; Bray NW; Li KZH; Fraser S; Pieruccini-Faria F; Berryman N; Lussier M; Shoemaker JK; Son S; Bherer L; | 37471089 PERFORM |
| 15 | Multiple routes to help you roam: A comparison of training interventions to improve cognitive-motor dual-tasking in healthy older adults | Downey R; Bherer L; Pothier K; Vrinceanu T; Intzandt B; Berryman N; Lussier M; Vincent T; Karelis AD; Nigam A; Vu TTM; Bosquet L; Li KZH; | 36408116 PERFORM |
| 16 | Mastering the Relationship between the Body and the Brain? The Case of a Female Master Athlete | Saillant K; Intzandt B; Bérubé B; Sanami S; Gauthier C; Bherer L; | 35950796 PERFORM |
| 17 | A comparison of the effect of physical activity and cognitive training on dual-task performance in older adults | Vrinceanu T; Blanchette CA; Intzandt B; Lussier M; Pothier K; Vu TTM; Nigam A; Bosquet L; Karelis AD; Li KZH; Berryman N; Bherer L; | 34865009 PERFORM |
| 18 | Assessment of the Relationship Between Executive Function and Cardiorespiratory Fitness in Healthy Older Adults | Predovan D; Berryman N; Lussier M; Comte F; Vu TTM; Villalpando JM; Bherer L; | 34803824 PERFORM |
| 19 | Sex moderations in the relationship between aortic stiffness, cognition, and cerebrovascular reactivity in healthy older adults | Sabra D; Intzandt B; Desjardins-Crepeau L; Langeard A; Steele CJ; Frouin F; Hoge RD; Bherer L; Gauthier CJ; | 34582484 PERFORM |
| 20 | Comparing the effect of Cognitive vs. Exercise Training on brain MRI outcomes in healthy older adults: A systematic review | Intzandt B; Vrinceanu T; Huck J; Vincent T; Montero-Odasso M; Gauthier CJ; Bherer L; | 34245760 PERFORM |
| 21 | A comparison of physical exercise and cognitive training interventions to improve determinants of functional mobility in healthy older adults | Pothier K; Vrinceanu T; Intzandt B; Bosquet L; Karelis AD; Lussier M; Vu TTM; Nigam A; Li KZH; Berryman N; Bherer L; | 33774144 PERFORM |
| 22 | Gait variability across neurodegenerative and cognitive disorders: Results from the Canadian Consortium of Neurodegeneration in Aging (CCNA) and the Gait and Brain Study. | Pieruccini-Faria F, Black SE, Masellis M, Smith EE, Almeida QJ, Li KZH, Bherer L, Camicioli R, Montero-Odasso M | 33590967 PSYCHOLOGY |
| 23 | A Cross-Sectional Study on the Impact of Arterial Stiffness on the Corpus Callosum, a Key White Matter Tract Implicated in Alzheimer's Disease | Badji A; de la Colina AN; Boshkovski T; Sabra D; Karakuzu A; Robitaille-Grou MC; Gros C; Joubert S; Bherer L; Lamarre-Cliche M; Stikov N; Gauthier CJ; Cohen-Adad J; Girouard H; | 32741837 PERFORM |
| 24 | Synergistic effects of cognitive training and physical exercise on dual-task performance in older adults | Bherer L; Gagnon C; Langeard A; Lussier M; Desjardins-Crépeau L; Berryman N; Bosquet L; Vu TTM; Fraser S; Li KZH; Kramer AF; | 32803232 PERFORM |
| 25 | Effects of Dance/Movement Training vs. Aerobic Exercise Training on cognition, physical fitness and quality of life in older adults: A randomized controlled trial. | Esmail A, Vrinceanu T, Lussier M, Predovan D, Berryman N, Houle J, Karelis A, Grenier S, Minh Vu TT, Villalpando JM, Bherer L | 31987547 PERFORM |
| 26 | Higher cardiovascular fitness level is associated with lower cerebrovascular reactivity and perfusion in healthy older adults. | Intzandt B, Sabra D, Foster C, Desjardins-Crépeau L, Hoge RD, Steele CJ, Bherer L, Gauthier CJ | 31342831 PERFORM |
| 27 | Guidelines for Gait Assessments in the Canadian Consortium on Neurodegeneration in Aging (CCNA). | Cullen S, Montero-Odasso M, Bherer L, Almeida Q, Fraser S, Muir-Hunter S, Li K, Liu-Ambrose T, McGibbon CA, McIlroy W, Middleton LE, Sarquis-Adamson Y, Beauchet O, McFadyen BJ, Morais JA, Camicioli R, Canadian Gait and Cognition Network | 29977431 ENCS |
| 28 | The Association between Generalized Anxiety Disorder, Subthreshold Anxiety Symptoms and Fear of Falling among Older Adults: Preliminary Results from a Pilot Study. | Payette MC, Bélanger C, Benyebdri F, Filiatrault J, Bherer L, Bertrand JA, Nadeau A, Bruneau MA, Clerc D, Saint-Martin M, Cruz-Santiago D, Ménard C, Nguyen P, Vu TTM, Comte F, Bobeuf F, Grenier S | 28452660 PERFORM |
| 29 | SYNERGIC TRIAL (SYNchronizing Exercises, Remedies in Gait and Cognition) a multi-Centre randomized controlled double blind trial to improve gait and cognition in mild cognitive impairment. | Montero-Odasso M, Almeida QJ, Burhan AM, Camicioli R, Doyon J, Fraser S, Li K, Liu-Ambrose T, Middleton L, Muir-Hunter S, McIlroy W, Morais JA, Pieruccini-Faria F, Shoemaker K, Speechley M, Vasudev A, Zou GY, Berryman N, Lussier M, Vanderhaeghe L, Bherer L | 29661156 PERFORM |
| 30 | Consensus on Shared Measures of Mobility and Cognition: From the Canadian Consortium on Neurodegeneration in Aging (CCNA). | Montero-Odasso M, Almeida QJ, Bherer L, Burhan AM, Camicioli R, Doyon J, Fraser S, Muir-Hunter S, Li KZH, Liu-Ambrose T, McIlroy W, Middleton L, Morais JA, Sakurai R, Speechley M, Vasudev A, Beauchet O, Hausdorff JM, Rosano C, Studenski S, Verghese J, Canadian Gait and Cognition Network | 30101279 PERFORM |
| 31 | Arterial stiffness and brain integrity: A review of MRI findings. | Badji A, Sabra D, Bherer L, Cohen-Adad J, Girouard H, Gauthier CJ | 31063866 PERFORM |
| 32 | Switching Ability Mediates the Age-Related Difference in Timed Up and Go Performance. | Langeard A, Houdeib R, Saillant K, Kaushal N, Lussier M, Bherer L | 30909238 PSYCHOLOGY |
| 33 | Brain gray matter volume associations with gait speed and related structural covariance networks in cognitively healthy individuals and in patients with mild cognitive impairment: A cross-sectional study. | Beauchet O, Montembeault M, Barden JM, Szturm T, Bherer L, Liu-Ambrose T, Chester VL, Li K, Helbostad JL, Allali G, Canadian Gait Consortium | 31075383 PSYCHOLOGY |
| 34 | Gross Motor Skills Training Leads to Increased Brain-Derived Neurotrophic Factor Levels in Healthy Older Adults: A Pilot Study. | Grégoire CA, Berryman N, St-Onge F, Vu TTM, Bosquet L, Arbour N, Bherer L | 31031639 PERFORM |
| 35 | Higher levels of cardiovascular fitness are associated with better executive function and prefrontal oxygenation in younger and older women. | Dupuy O, Gauthier CJ, Fraser SA, Desjardins-Crèpeau L, Desjardins M, Mekary S, Lesage F, Hoge RD, Pouliot P, Bherer L | 25741267 PERFORM |
| 36 | Relationships between lower body strength and the energy cost of treadmill walking in a cohort of healthy older adults: a cross-sectional analysis. | Berryman N, Bherer L, Nadeau S, Lauzière S, Lehr L, Bobeuf F, Kergoat MJ, Vu TT, Bosquet L | 27815704 PERFORM |
| 37 | A review of the effects of physical activity and exercise on cognitive and brain functions in older adults. | Bherer L, Erickson KI, Liu-Ambrose T | 24102028 PERFORM |
| 38 | Physical exercise and brain functions in older adults. | Bherer L, Erickson KI, Liu-Ambrose T | 24163767 PERFORM |
| 39 | Age-related decline in divided-attention: from theoretical lab research to practical real-life situations. | Fraser S, Bherer L | 26304268 PERFORM |
| 40 | Glycaemic control and self-management behaviours in Type 2 diabetes: results from a 1-year longitudinal cohort study. | Houle J, Beaulieu MD, Chiasson JL, Lespérance F, Côté J, Strychar I, Bherer L, Meunier S, Lambert J | 25581545 PERFORM |
| 41 | Cognitive plasticity in older adults: effects of cognitive training and physical exercise. | Bherer L | 25773610 PERFORM |
| 42 | The relationship between exercise intensity, cerebral oxygenation and cognitive performance in young adults. | Mekari S, Fraser S, Bosquet L, Bonnéry C, Labelle V, Pouliot P, Lesage F, Bherer L | 26063061 PERFORM |
| 43 | Cerebral Hemodynamics During Exercise and Recovery in Heart Transplant Recipients. | Gayda M, Desjardins A, Lapierre G, Dupuy O, Fraser S, Bherer L, Juneau M, White M, Gremeaux V, Labelle V, Nigam A | 26577897 PERFORM |
| 44 | Limited Benefits of Heterogeneous Dual-Task Training on Transfer Effects in Older Adults. | Lussier M, Brouillard P, Bherer L | 26603017 PERFORM |
| 45 | Differences between chronological and brain age are related to education and self-reported physical activity. | Steffener J, Habeck C, O'Shea D, Razlighi Q, Bherer L, Stern Y | 26973113 PERFORM |
| 46 | Socioeconomic status and glycemic control in adult patients with type 2 diabetes: a mediation analysis. | Houle J, Lauzier-Jobin F, Beaulieu MD, Meunier S, Coulombe S, Côté J, Lespérance F, Chiasson JL, Bherer L, Lambert J | 27239316 PERFORM |
| 47 | Specific transfer effects following variable priority dual-task training in older adults. | Lussier M, Bugaiska A, Bherer L | 27372514 PERFORM |
| 48 | Drivers with Amnestic Mild Cognitive Impairment Can Benefit from a Multiple-Session Driving Simulator Automated Training Program. | Teasdale N, Simoneau M, Hudon L, Moszkowicz T, Laurendeau D, Germain Robitaille M, Bherer L, Duchesne S, Hudon C | 27564992 PERFORM |
| 49 | Anti-Dementia Drugs, Gait Performance and Mental Imagery of Gait: A Non-Randomized Open-Label Trial. | Beauchet O, Barden J, Liu-Ambrose T, Chester VL, Annweiler C, Szturm T, Grenier S, Léonard G, Bherer L, Allali G, Canadian Gait Consortium | 27568453 PERFORM |
| 50 | Longitudinal testing of the Information-Motivation-Behavioral Skills model of self-care among adults with type 2 diabetes. | Meunier S, Coulombe S, Beaulieu MD, Côté J, Lespérance F, Chiasson JL, Bherer L, Lambert J, Houle J | 27373961 PERFORM |
| 51 | Association Between Falls and Brain Subvolumes: Results from a Cross-Sectional Analysis in Healthy Older Adults. | Beauchet O, Launay CP, Barden J, Liu-Ambrose T, Chester VL, Szturm T, Grenier S, Léonard G, Bherer L, Annweiler C, Helbostad JL, Verghese J, Allali G, Biomathics and Canadian Gait Consortium | 27785698 PERFORM |
| 52 | Cognitive function in patients with stable coronary heart disease: Related cerebrovascular and cardiovascular responses. | Gayda M, Gremeaux V, Bherer L, Juneau M, Drigny J, Dupuy O, Lapierre G, Labelle V, Fortier A, Nigam A | 28937981 PERFORM |
| 53 | A comparison of the impact of physical exercise, cognitive training and combined intervention on spontaneous walking speed in older adults. | Pothier K, Gagnon C, Fraser SA, Lussier M, Desjardins-Crépeau L, Berryman N, Kergoat MJ, Vu TTM, Li KZH, Bosquet L, Bherer L | 29235076 PERFORM |
| 54 | Cognitive Involvement in Balance, Gait and Dual-Tasking in Aging: A Focused Review From a Neuroscience of Aging Perspective | Li KZH; Bherer L; Mirelman A; Maidan I; Hausdorff JM; | 30425679 PERFORM |
| Title: | Synergistic effects of exercise, cognitive training and vitamin D on gait performance and falls in mild cognitive impairment-secondary outcomes from the SYNERGIC trial | ||||
| Authors: | Pieruccini-Faria F, Son S, Zou G, Almeida QJ, Middleton LE, Bray NW, Lussier M, Shoemaker JK, Speechley M, Liu-Ambrose T, Burhan AM, Camicioli R, Li KZH, Fraser S, Berryman N, Bherer L, Montero-Odasso M | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/40966614/ | ||||
| DOI: | 10.1093/ageing/afaf242 | ||||
| Publication: | Age and ageing | ||||
| Keywords: | Falls; Mild Cognitive Impairment; cognitive; exercises; gait; older people; training; vitamin D; | ||||
| PMID: | 40966614 | Category: | Date Added: | 2025-09-18 | |
| Dept Affiliation: |
SOH
1 Department of Medicine, Division of Geriatric Medicine, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada. 2 Parkwood Institute, Gait and Brain Laboratory, London, Ontario, Canada. 3 Western University, Schulich School of Medicine and Dentistry, Department of Epidemiology and Biostatistics, London, Ontario, Canada. 4 Alimentiv Inc., London, Ontario, Canada. 5 Carespace Health and Wellness Neurodegeneration Clinics, Waterloo, Ontario, Canada. 6 Department of Kinesiology and Health Sciences, University of Waterloo, Waterloo, Ontario, Canada. 7 Schlegel-UW Research Institute for Aging, Waterloo, Ontario, Canada. 8 Recovery and Performance Laboratory, Biomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada. 9 Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Université de Montréal, Montreal, Quebec, Canada. 10 École de Réadaptation, Faculté de Médecine, Université de Montréal, Montreal, Québec, Canada. 11 School of Kinesiology, University of Western Ontario, London, Ontario, Canada. 12 Department of Epidemiology and Biostatistics, and Schulich Interfaculty Program in Public Health, Western University, London, Ontario, Canada. 13 Department of Physical Therapy, University of British Columbia, Vancouver, British Columbia, Canada. 14 Djavad Mowafaghian Centre for Brain Health, Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada. 15 Centre for Aging SMART at Vancouver Coastal Health, Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada. 16 Ontario Shores Centre for Mental Health Sciences, Whitby, Ontario, Canada. 17 Department of Psychiatry, Temerity Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. 18 Department of Medicine and Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Alberta, Canada. 19 Department of Psychology, Concordia University, Montréal, Québec, Canada. 20 Interdisciplinary School of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada. 21 Département des Sciences de l'Activité Physique, Université du Québec à Montréal, Montréal, Québec, Canada. 22 Institut national du sport du Québec, Montréal, Québec, Canada. 23 Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montréal, Québec, Canada. 24 Centre de Recherche, Institut de Cardiologie de Montréal, Montréal, Québec, Canada. 25 Département de Médecine, Université de Montréal, Montréal, Québec, Canada. |
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Description: |
Background: Older adults with mild cognitive impairment (MCI) have a higher risk of gait impairments and falls; yet, the effects of multimodal interventions, including combinations of exercises with cognitive training, on improving their mobility remain unclear. Objectives: To investigate the synergistic effects of aerobic-resistance exercise combined with cognitive training, with or without vitamin D supplementation, on gait performance and falls risk in older adults with MCI. Methods: The effect of 20 weeks of aerobic-resistance exercise, cognitive training, and Vitamin D supplementation (10 000 IU 3×/week) on gait and falls in older adults with MCI was evaluated in the SYNERGIC trial, using a fractional factorial design. Assessments were conducted at baseline, 6-month endpoint (after intervention) and 12-month endpoint (follow-up). Eligible participants were between the ages of 65 and 84 years with MCI enrolled from 19 September 2016 to 7 April 2020. Main outcomes of interest for gait performance were gait speed and gait variability changes, whilst for falls were incidental falls and incidental injurious falls. Results: Amongst 161 participants, the four exercise-based arms improved gait speed (+7.5 cm/s, P < .001) and reduced falls (incidence rate ratios (IRR) = 0.65, 95% confidence interval (CI): 0.32-1.42, P = .25) and injurious falls (IRR = 0.38, 95% CI: 0.15-1.05, P = .05) at 6-month endpoint. Falls reduction reached statistical significance (IRR = 0.28, 95% CI: 0.13-0.64, P = .002) at 12-month endpoint. Exercises combined with cognitive training showed the greatest gains in gait speed at 6-month endpoint (P < .001) and in reducing falls at 12-month endpoint (IRR = 0.24, 95% CI: 0.05-0.77, P = .02) compared to the control. Vitamin D did not enhance outcomes and increased gait variability, a marker of instability. Conclusion: Aerobic-resistance exercise combined with sequential computerised cognitive training improved gait performance at 6 months and decreased the risk of falls and injuries at 12 months in older adults with MCI. The addition of vitamin D did not produce benefits. |
