| Keyword search (4,163 papers available) | ![]() |
"An H" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Impact of COVID-19 on incidence and trends of adverse events among hospitalised patients in Calgary, Canada: a retrospective chart review study | Wu G; Eastwood CA; Cheligeer C; Southern DA; Zeng Y; Ghali WA; Bakal JA; Boussat B; Flemons W; Forster A; Xu Y; Quan H; | 41592994 CONCORDIA |
| 2 | Establishing work productivity loss norms: Absenteeism and presenteeism in a Canadian working population | Zhang W; Qian H; L' Heureux J; Johns G; Koehoorn M; Woodcock S; | 41469277 JMSB |
| 3 | Preprocessing narrative texts in electronic medical records to identify hospital adverse events: A scoping review | Jafarpour H; Wu G; Cheligeer CK; Yan J; Xu Y; Southern DA; Eastwood CA; Zeng Y; Quan H; | 41072367 ENCS |
| 4 | Pseudocapacitive MXene@Fe-TA ternary mediator enhances denitrification via optimized electron transfer and microbial regulation in wastewater treatment | Pan S; Wang X; Guo T; An H; Guo Y; Chen Z; Lian J; Guo J; | 41043789 ENCS |
| 5 | A dataset from a coordinated multi-site laboratory study investigating the Hue-Heat-Hypothesis | Bavaresco M; Cureau RJ; Pigliautile I; Barna E; Deme Belafi Z; Belussi L; Chinazzo G; Chiucchiù A; Danza L; Deng Z; Dong B; Gapski NH; Garlet L; Gnecco VM; Guo X; Pilehchi Ha P; Karimian H; Lamberts R; Liu S; da Costa Loeser B; Massucci C; Melo AP; Nagy BV; Ouf MM; Salamone F; Schweiker M; Pisello AL; | 40973711 ENCS |
| 6 | Adaptive finite-time synchronized control of multi-robotic fiber placement system with model uncertainties and disturbances | Zhang R; Wang Y; Xie W; Li P; Tan H; Jiang Y; | 40461302 ENCS |
| 7 | Utilizing large language models for detecting hospital-acquired conditions: an empirical study on pulmonary embolism | Cheligeer C; Southern DA; Yan J; Wu G; Pan J; Lee S; Martin EA; Jafarpour H; Eastwood CA; Zeng Y; Quan H; | 40105654 ENCS |
| 8 | Impact of a national dementia research consortium: The Canadian Consortium on Neurodegeneration in Aging (CCNA) | Chertkow H; Phillips N; Rockwood K; Anderson N; Andrew MK; Bartha R; Beaudoin C; Bélanger N; Bellec P; Belleville S; Bergman H; Best S; Bethell J; Bherer L; Black S; Borrie M; Camicioli R; Carrier J; Cashman N; Chan S; Crowshoe L; Cuello C; Cynader M; Dang-Vu T; Das S; Dixon RA; Ducharme S; Einstein G; Evans AC; Fahnestock M; Feldman H; Ferland G; Finger E; Fisk JD; Fogarty J; Fon E; Gan-Or Z; Gauthier S; Greenwood C; Henri-Bellemare C; Herrmann N; Hogan DB; Hsiung R; Itzhak I; Jacklin K; Lanctôt K; Lim A; MacKenzie I; Masellis M; Maxwell C; McAiney C; McGilton K; McLaurin J; Mihailidis A; Mohades Z; Montero-Odasso M; Morgan D; Naglie G; Nygaard H; O' Connell M; Petersen R; Pilon R; Rajah MN; Rapoport M; Roach P; Robillard JM; Rogaeva E; Rosa-Neto P; Rylett J; Sadavoy J; St George-Hyslop P; Seitz D; Smith E; Stefanovic B; Vedel I; Walker JD; Wellington C; Whitehead V; Wittich W; | 39636028 HKAP |
| 9 | Identifying personalized barriers for hypertension self-management from TASKS framework | Yang J; Zeng Y; Yang L; Khan N; Singh S; Walker RL; Eastwood R; Quan H; | 39143621 ENCS |
| 10 | Myelin basic protein mRNA levels affect myelin sheath dimensions, architecture, plasticity, and density of resident glial cells | Bagheri H; Friedman H; Hadwen A; Jarweh C; Cooper E; Oprea L; Guerrier C; Khadra A; Collin A; Cohen-Adad J; Young A; Victoriano GM; Swire M; Jarjour A; Bechler ME; Pryce RS; Chaurand P; Cougnaud L; Vuckovic D; Wilion E; Greene O; Nishiyama A; Benmamar-Badel A; Owens T; Grouza V; Tuznik M; Liu H; Rudko DA; Zhang J; Siminovitch KA; Peterson AC; | 39023138 CSBN |
| 11 | Translating the Interplay of Cognition and Physical Performance in COPD and Interstitial Lung Disease: Meeting Report and Literature Review | Rozenberg D; Reid WD; Camp P; Campos JL; Dechman G; Davenport PW; Egan H; Fisher JH; Guenette JA; Gold D; Goldstein RS; Goodridge D; Janaudis-Ferreira T; Kaplan AG; Langer D; Marciniuk DD; Moore B; Orchanian-Cheff A; Otoo-Appiah J; Pepin V; Rassam P; Rotenberg S; Ryerson C; Spruit MA; Stanbrook MB; Stickland MK; Tom J; Wentlandt K; | 38901488 HKAP |
| 12 | An Automated Single-Cell Droplet-Digital Microfluidic Platform for Monoclonal Antibody Discovery | Ahmadi F; Tran H; Letourneau N; Little SR; Fortin A; Moraitis AN; Shih SCC; | 38441226 BIOLOGY |
| 13 | How to present work productivity loss results from clinical trials for patients and caregivers? A mixed methods approach | L' Heureux J; McTaggart-Cowan H; Johns G; Chen L; Steiner T; Tocher P; Sun H; Zhang W; | 37276772 JMSB |
| 14 | Surgical margin assessment of bone tumours: A systematic review of current and emerging technologies | Shoman H; Al-Kassmy J; Ejaz M; Matta J; Alakhras S; Kahla K; D' Acunto M; | 36845345 ENCS |
| 15 | Design Principles in mHealth Interventions for Sustainable Health Behavior Changes: Protocol for a Systematic Review | Yang L; Kuang A; Xu C; Shewchuk B; Singh S; Quan H; Zeng Y; | 36811938 ENCS |
| 16 | Developing EMR-based algorithms to Identify hospital adverse events for health system performance evaluation and improvement: Study protocol | Wu G; Eastwood C; Zeng Y; Quan H; Long Q; Zhang Z; Ghali WA; Bakal J; Boussat B; Flemons W; Forster A; Southern DA; Knudsen S; Popowich B; Xu Y; | 36197944 ENCS |
| 17 | Data Analysis and Knowledge Mining of Machine Learning in Soil Corrosion Factors of the Pipeline Safety | Zhao Z; Chen M; Fan H; Zhang N; | 35571701 ENCS |
| 18 | Application of Machine Learning in the Reliability Evaluation of Pipelines for the External Anticorrosion Coating | Zhao Z; Chen M; Fan H; Zhang N; | 35371236 ENCS |
| 19 | Consensus Statement Regarding the Application of Biogen to Health Canada for Approval of Aducanumab | Chertkow H; Rockwood K; Hogan DB; Phillips N; Montero-Odasso M; Amanullah S; Black S; Bocti C; Borrie M; Feldman H; Freedman M; Hsiung R; Kirk A; Masellis M; Nygaard H; Rajji T; Verret L; | 34912492 PSYCHOLOGY |
| 20 | COSORE: A community database for continuous soil respiration and other soil-atmosphere greenhouse gas flux data. | Bond-Lamberty B, Christianson DS, Malhotra A, Pennington SC, Sihi D, AghaKouchak A, Anjileli H, Altaf Arain M, Armesto JJ, Ashraf S, Ataka M, Baldocchi D, Andrew Black T, Buchmann N, Carbone MS, Chang SC, Crill P, Curtis PS, Davidson EA, Desai AR, Drake JE, El-Madany TS, Gavazzi M, Görres CM, Gough CM, Goulden M, Gregg J, Gutiérrez Del Arroyo O, He JS, Hirano T, Hopple A, Hughes H, Järveoja J, Jassal R, Jian J, Kan H, Kaye J, Kominami Y, Liang N, Lipson D, Macdonald CA, Maseyk K, Mathes K, Mauritz M, Mayes | 33026137 ENCS |
| 21 | Antagonistic interactions between two MAP kinase cascades in plant development and immune signaling. | Sun T, Nitta Y, Zhang Q, Wu D, Tian H, Lee JS, Zhang Y | 29789386 BIOLOGY |
| 22 | Effects of pool size and spacing on burning rate and flame height of two square heptane pool fires. | Wan H, Gao Z, Ji J, Zhang Y, Li K, Wang L | 30776594 ENCS |
| 23 | Mms21: A Putative SUMO E3 Ligase in Candida albicans That Negatively Regulates Invasiveness and Filamentation, and Is Required for the Genotoxic and Cellular Stress Response. | Islam A, Tebbji F, Mallick J, Regan H, Dumeaux V, Omran RP, Whiteway M | 30530734 PERFORM |
| Title: | An Automated Single-Cell Droplet-Digital Microfluidic Platform for Monoclonal Antibody Discovery | ||||
| Authors: | Ahmadi F, Tran H, Letourneau N, Little SR, Fortin A, Moraitis AN, Shih SCC | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/38441226/ | ||||
| DOI: | 10.1002/smll.202308950 | ||||
| Publication: | Small (Weinheim an der Bergstrasse, Germany) | ||||
| Keywords: | antibody discovery; deterministic co-encapsulation; droplet operations; droplet-based microfluidics; | ||||
| PMID: | 38441226 | Category: | Date Added: | 2024-03-05 | |
| Dept Affiliation: |
BIOLOGY
1 Department of Electrical and Computer Engineering, Concordia University, 1455 de Maisonneuve Blvd. West, Montréal, Québec, H3G 1M8, Canada. 2 Centre for Applied Synthetic Biology, Concordia University, 7141 Sherbrooke Street West, Montréal, Québec, H4B 1R6, Canada. 3 Department of Biology, Concordia University, 7141 Sherbrooke Street West, Montréal, Québec, H4B 1R6, Canada. 4 Human Health Therapeutics Research Centre, National Research Council Canada, Montréal, Québec, H4P 2R2, Canada. |
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Description: |
Monoclonal antibody (mAb) discovery plays a prominent role in diagnostic and therapeutic applications. Droplet microfluidics has become a standard technology for high-throughput screening of antibody-producing cells due to high droplet single-cell confinement frequency and rapid analysis and sorting of the cells of interest with their secreted mAbs. In this work, a new method is described for on-demand co-encapsulation of cells that eliminates the difficulties associated with washing in between consecutive steps inside the droplets and enables the washing and addition of fresh media. The new platform identifies hybridoma cells that are expressing antibodies of interest using antibody-characterization assays to find the best-performing or rare-cell antibody candidates. |



