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Optogenetic stimulation of infralimbic cortex projections to the paraventricular thalamus attenuates context-induced renewal

Author(s): Brown A; Chaudhri N;

Contexts associated with prior reinforcement can renew extinguished conditioned responding. The prelimbic (PL) and infralimbic (IL) cortices are thought to mediate the expression and suppression of conditioned responding, respectively. Evidence suggests that PL inputs to the paraventricular nucleus of the thalamus (PVT) drive the expression of cue-induced ...

Article GUID: 36373226


Corticostriatal suppression of appetitive Pavlovian conditioned responding

Author(s): Villaruel FR; Martins M; Chaudhri N;

The capacity to suppress learned responses is essential for animals to adapt in dynamic environments. Extinction is a process by which animals learn to suppress conditioned responding when an expected outcome is omitted. The infralimbic cortex (IL) to nucleus accumbens shell (NAcS) neural circuit is implicated in suppressing conditioned responding after e ...

Article GUID: 34880119


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