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Challenges and Approaches in the Study of Neural Entrainment

Author(s): Duecker K; Doelling KB; Breska A; Coffey EBJ; Sivarao DV; Zoefel B;

When exposed to rhythmic stimulation, the human brain displays rhythmic activity across sensory modalities and regions. Given the ubiquity of this phenomenon, how sensory rhythms are transformed into neural rhythms remains surprisingly inconclusive. An influential model posits that endogenous oscillations entrain to external rhythms, thereby encoding envi ...

Article GUID: 39358026


Dopamine dysregulation in Parkinson's disease flattens the pleasurable urge to move to musical rhythms

Author(s): Pando-Naude V; Matthews TE; Højlund A; Jakobsen S; Østergaard K; Johnsen E; Garza-Villarreal EA; Witek MAG; Penhune V; Vuust P;

The pleasurable urge to move to music (PLUMM) activates motor and reward areas of the brain and is thought to be driven by predictive processes. Dopamine in motor and limbic networks is implicated in beat-based timing and music-induced pleasure, suggesting a central role of basal ganglia (BG) dop ...

Article GUID: 37724707


Respiratory sinus arrhythmia, negative social interactions, and fluctuations in unmet interpersonal needs: A daily diary study

Author(s): MacNeil S; Renaud J; Gouin JP;

Introduction: This study examined daily fluctuations in the unmet interpersonal needs of thwarted belongingness and perceived burdensomeness in response to daily negative social interactions, as well as the moderating role of respiratory sinus arrhythmia (RSA) across adolescents at lower and higher risk for suicidal ideation. Methods: Fifty five adolesce ...

Article GUID: 37208985


Respiratory sinus arrhythmia moderates the interpersonal consequences of brooding rumination

Author(s): Caldwell W; MacNeil S; Wrosch C; McGrath JJ; Dang-Vu TT; Morin AJS; Gouin JP;

Brooding rumination is an intrapersonal emotion regulation strategy associated with negative interpersonal consequences. Resting respiratory sinus arrhythmia (RSA), a psychophysiological marker of self-regulatory capacity, may buffer the association between maladaptive emotion regulation and negative interpersonal behaviors. The current work examines the ...

Article GUID: 36844897


Sleep disorders in patients with a neurocognitive disorder

Author(s): C Moderie

CONCLUSION: Multiple and sustained nonpharmacological approaches are recommended for the treatment of sleep disturbances in patients with neurocognitive disorder. Pharmacological indications remain limited, and further randomized clinical trials integrating a multimodal approach are warranted to evaluate the treatment of sleep disorders in specific neuroc ...

Article GUID: 34916075


Maturation of temporal saccade prediction from childhood to adulthood: predictive saccades, reduced pupil size and blink synchronization

Author(s): Calancie OG; Brien DC; Huang J; Coe BC; Booij L; Khalid-Khan S; Munoz DP;

When presented with a periodic stimulus, humans spontaneously adjust their movements from reacting to predicting the timing of its arrival, but little is known about how this sensorimotor adaptation changes across development. To investigate this, we analyzed saccade behavior in 114 healthy humans (ages 6-24 years) performing the visual metronome task, wh ...

Article GUID: 34759032


In utero Exposure to Valproic-Acid Alters Circadian Organisation and Clock-Gene Expression: Implications for Autism Spectrum Disorders

Author(s): Ferraro S; de Zavalia N; Belforte N; Amir S;

Autism Spectrum Disorder (ASD) is a pervasive neurodevelopmental disorder characterised by restrictive patterns of behaviour and alterations in social interaction and communication. Up to 80% of children with ASD exhibit sleep-wake cycle disturbances, emphasising the pressing need for novel approaches in the treatment of ASD-associated comorbidities. Whil ...

Article GUID: 34650409


Heart rate variability moderates the between- and within-person associations between daily stress and negative affect

Author(s): da Estrela C; MacNeil S; Gouin JP;

Stress exposure increases risk for depressive symptoms. However, there are substantial individual differences in affective responses to stress. High-frequency heart rate variability (HF-HRV), a marker of vagally-mediated parasympathetic activity, has been conceptualized as a psychophysiological index of emotion regulation that may moderate individuals' ...

Article GUID: 33556470


Cerebellar Cortex 4-12 Hz Oscillations and Unit Phase Relation in the Awake Rat.

Author(s): Lévesque M; Gao H; Southward C; Langlois JMP; Léna C; Courtemanche R;

Oscillations in the granule cell layer (GCL) of the cerebellar cortex have been related to behavior and could facilitate communication with the cerebral cortex. These local field potential (LFP) oscillations, strong at 4-12 Hz in the rodent cerebellar cortex during awake immobility, should also be an indicator of an underlying influence on the patterns of ...

Article GUID: 33240052


The phenotype associated with variants in TANGO2 may be explained by a dual role of the protein in ER-to-Golgi transport and at the mitochondria.

Author(s): Milev MP, Saint-Dic D, Zardoui K, Klopstock T, Law C, Distelmaier F, Sacher M

TANGO2 variants result in a complex disease phenotype consisting of recurrent crisis-induced rhabdomyolysis, encephalopathy, seizures, lactic acidosis, hypoglycemia, and cardiac arrhythmias. Although first described in a fruit fly model as a protein necessary for some aspect of Golgi function and organization, its role in the cell at a fundamental level h ...

Article GUID: 32909282


Heart Rate Variability, Sleep Quality, and Depression in the Context of Chronic Stress

Author(s): da Estrela C; McGrath J; Booij L; Gouin JP;

Background: Disrupted sleep quality is one of the proposed mechanisms through which chronic stress may lead to depression. However, there exist significant individual differences in sleep reactivity, which is the extent to which one experiences sleep disturbances in response to stress. Purpose: The aim of the current study was to investigate whether low ...

Article GUID: 32525208


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