Author(s): Tarmoun K; Lachance V; Le Corvec V; BĂ©langer SM; Beaucaire G; Kourrich S;
Sigma-1R (S1R) is a ubiquitously distributed protein highly expressed in the brain and liver. It acts as a ligand-inducible chaperone protein localized at the endoplasmic reticulum. S1R participates in several signaling pathways that oversee diverse cellula ...
Article GUID: 39335377
Author(s): Parrott JM; Benson-Davies S; O' Kane M; Sherf-Dagan S; Ben-Porat T; Arcone VM; Faria SL; Parrott JS; ...
Background: Clinical practice recommendations for macronutrient intake in Metabolic and Bariatric Surgery (MBS) are insufficiently grounded in the research, possibly due to a pauci ...
Article GUID: 39262138
Author(s): Bin X; Pawelek PD;
Enterobactin is a high-affinity iron chelator produced and secreted by Escherichia coli and Salmonella typhimurium to scavenge scarce extracellular Fe3+ as a micronutrient. EntC and EntB are the first two enzymes in the enterobactin biosynthetic pathway. Is ...
Article GUID: 39031458
Author(s): Bagheri H; Friedman H; Hadwen A; Jarweh C; Cooper E; Oprea L; Guerrier C; Khadra A; Collin A; Cohen-Adad J; Young A; Victoriano GM; Swire M; ...
Myelin basic protein (Mbp) is essential for both elaboration and maintenance of CNS myelin, and its reduced accumulation results in hypomyelination. How different Mbp mRNA levels affect myelin dime ...
Article GUID: 39023138
Author(s): Kozlov G; Jiang J; Rutherford T; Noronha AM; Wilds CJ; Gehring K;
La-related proteins (LARPs) are a family of RNA-binding proteins that share a conserved La motif (LaM) domain. LARP1 plays a role in regulating ribosomal protein synthesis and stabilizing mRNAs and has a unique structure without an RNA binding RRM domain ad ...
Article GUID: 39016322
Author(s): Logan CJ; Staton CC; Oliver JT; Bouffard J; Kazmirchuk TDD; Magi M; Brett CL;
The budding yeast Saccharomyces cerevisiae is a proven model organism for elucidating conserved eukaryotic biology, but to date its extracellular vesicle (EV) biology is understudied. Here, we show yeast transmit information through the extracellular medium ...
Article GUID: 38711329
Author(s): Ghazikhani H; Butler G;
This study introduces TooT-PLM-ionCT, a comprehensive framework that consolidates three distinct systems, each meticulously tailored for one of the following tasks: distinguishing ion channels (ICs) from membrane proteins (MPs), segregating ion transporters ...
Article GUID: 38656743
Author(s): Leake J; Leidl DM; Lay BPP; Fam JP; Giles MC; Qureshi OA; Westbrook RF; Holmes NM;
Activity in the basolateral amygdala complex (BLA) is needed to encode fears acquired through contact with both innate sources of danger (i.e., things that are painful) and learned sources of danger (e.g., being threatened with a gun). However, within the B ...
Article GUID: 37963767
Author(s): Brunetti SC; Arseneault MKM; Gulick PJ;
The caleosins are encoded by multi-gene families in Arabidopsis thaliana and other plant species. This work investigates the role of two family members, RD20/CLO3 and CLO7, in flowering transition and in root development in response to ABA treatment. Gene e ...
Article GUID: 37812854
Author(s): Jager K; Orozco-Hidalgo MT; Springstein BL; Joly-Smith E; Papazotos F; McDonough E; Fleming E; McCallum G; Yuan AH; Hilfinger A; Hochschild ...
Prions are self-propagating protein aggregates formed by specific proteins that can adopt alternative folds. Prions were discovered as the cause of the fatal transmissible spongiform encephalopathi ...
Article GUID: 37738299
Author(s): Ghazikhani H; Butler G;
Transmembrane transport proteins (transporters) play a crucial role in the fundamental cellular processes of all organisms by facilitating the transport of hydrophilic substrates across hydrophobic membranes. Despite the availability of numerous membrane pr ...
Article GUID: 37497772
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