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Neural correlates of recall and extinction in a rat model of appetitive Pavlovian conditioning

Author(s): Brown A; Villaruel FR; Chaudhri N;

Extinction is a fundamental form of inhibitory learning that is important for adapting to changing environmental contingencies. While numerous studies have investigated the neural correlates of extinction using Pavlovian fear conditioning and appetitive operant reward-seeking procedures, less is known about the neural circuitry mediating the extinction of ...

Article GUID: 36496079


The rodent medial prefrontal cortex and associated circuits in orchestrating adaptive behavior under variable demands

Author(s): Howland JG; Ito R; Lapish CC; Villaruel FR;

Emerging evidence implicates rodent medial prefrontal cortex (mPFC) in tasks requiring adaptation of behavior to changing information from external and internal sources. However, the computations within mPFC and subsequent outputs that determine behavior are incompletely understood. We review the involvement of mPFC subregions, and their projections to th ...

Article GUID: 35131398


Corticostriatal suppression of appetitive Pavlovian conditioned responding

Author(s): Villaruel FR; Martins M; Chaudhri N;

The capacity to suppress learned responses is essential for animals to adapt in dynamic environments. Extinction is a process by which animals learn to suppress conditioned responding when an expected outcome is omitted. The infralimbic cortex (IL) to nucleus accumbens shell (NAcS) neural circuit is implicated in suppressing conditioned responding after e ...

Article GUID: 34880119


Off-Target Influences of Arch-Mediated Axon Terminal Inhibition on Network Activity and Behavior.

Author(s): Lafferty CK, Britt JP

Front Neural Circuits. 2020;14:10 Authors: Lafferty CK, Britt JP

Article GUID: 32269514


Nucleus Accumbens Cell Type- and Input-Specific Suppression of Unproductive Reward Seeking.

Author(s): Lafferty CK, Yang AK, Mendoza JA, Britt JP

Cell Rep. 2020 Mar 17;30(11):3729-3742.e3 Authors: Lafferty CK, Yang AK, Mendoza JA, Britt JP

Article GUID: 32187545


Hippocampal Input to the Nucleus Accumbens Shell Enhances Food Palatability.

Author(s): Yang AK, Mendoza JA, Lafferty CK, Lacroix F, Britt JP

Biol Psychiatry. 2019 Sep 19;: Authors: Yang AK, Mendoza JA, Lafferty CK, Lacroix F, Britt JP

Article GUID: 31699294


Neurotensin in the nucleus accumbens reverses dopamine supersensitivity evoked by antipsychotic treatment.

Author(s): Servonnet A, Minogianis EA, Bouchard C, Bédard AM, Lévesque D, Rompré PP, Samaha AN

Neuropharmacology. 2017 Sep 01;123:10-21 Authors: Servonnet A, Minogianis EA, Bouchard C, Bédard AM, Lévesque D, Rompré PP, Samaha AN

Article GUID: 28522313


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