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Neuroinflammation and oxidative redox imbalance drive memory dysfunction in adolescent rats prenatally exposed to Datura Stramonium

Author(s): Bamisi O; Oluwalabani AO; Arogundade TT; Olajide OJ;

Although there have been reports indicating that Datura Stramonium (D. stramonium) may induce anticholinergic and neuropsychiatry effects, the compound is still being used for recreational and medicinal purposes while ingestion during pregnancy has been documented. Intriguingly, minimal studies have investigated the potential neurotoxic impact of D. stram ...

Article GUID: 39303770


TANGO2 deficiency disease is predominantly caused by a lipid imbalance

Author(s): Sacher M; DeLoriea J; Mehranfar M; Casey C; Naaz A; Gamberi C;

TANGO2 deficiency disease (TDD) is a rare genetic disorder estimated to affect ~8000 individuals worldwide. It causes neurodegeneration often accompanied by potentially lethal metabolic crises that are triggered by diet or illness. Recent work has demonstrated distinct lipid imbalances in multiple model systems either depleted for or devoid of the TANGO2 ...

Article GUID: 38836374


Removal of Nutrients from Water Using Biosurfactant Micellar-Enhanced Ultrafiltration

Author(s): Binte Rafiq Era S; Mulligan CN;

The removal of NH4+, NO3-, and NH3- from wastewater can be difficult and expensive. Through physical, chemical, and biological processes, metals and nutrients can be extracted from wastewater. Very few scientific investigations have employed surfactants with high biodegradability, low toxicity, and suitability for ion removal from wastewater at different ...

Article GUID: 36838547


Overview of Sigma-1R Subcellular Specific Biological Functions and Role in Neuroprotection

Author(s): Véronik Lachance

For the past several years, fundamental research on Sigma-1R (S1R) protein has unveiled its necessity for maintaining proper cellular homeostasis through modulation of calcium and lipid exchange between the endoplasmic reticulum (ER) and mitochondria, ER-stress response, and many other mechanisms. Most of these processes, such as ER-stress response and au ...

Article GUID: 36768299


Utilization of a biosurfactant foam/nanoparticle mixture for treatment of oil pollutants in soil

Author(s): Vu KA; Mulligan CN;

Oil contamination has become a primary environmental concern due to increased exploration, production, and use. When oil enters the soil, it may attach or adsorb to soil particles and stay in the soil for an extended period, contaminating the soil and surrounding areas. Nanoparticles have been widely used for the treatment of organic pollutants in the soi ...

Article GUID: 35834082


Mechanisms of hypericin incorporation to explain the photooxidation outcomes in phospholipid biomembrane models

Author(s): Pereira LSA; Camacho SA; Almeida AM; Gonçalves RS; Caetano W; DeWolf C; Aoki PHB;

Cell membranes are the first barriers for drug binding and key for the action of photosensitizers (PS). Herein, we report on the incorporation of the PS hypericin into Langmuir monolayers of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (DOPS), to represen ...

Article GUID: 35167859


Caloric restriction causes a distinct reorganization of the lipidome in quiescent and non-quiescent cells of budding yeast

Author(s): Mohammad K; Orfanos E; Titorenko VI;

After budding yeast cells cultured in a nutrient-rich liquid medium with 0.2% glucose (under caloric restriction conditions) or 2% glucose (under non-caloric restriction conditions), ferment glucose to ethanol and then consume ethanol, they enter the stationary phase. The process of their chronological aging begins. At that point, the yeast culture starts ...

Article GUID: 34853658


A green initiative for oiled sand cleanup using chitosan/rhamnolipid complex dispersion with pH-stimulus response

Author(s): Chen Z; An C; Wang Y; Zhang B; Tian X; Lee K;

The released oil can affect the vulnerable shoreline environment if the oil spills happen in coastal waters. The stranded oil on shorelines is persistent, posing a long-term influence on the intertidal ecosystem after weathering. Therefore, shoreline cleanup techniques are required to remove the oil from the shoreline environment. In this study, a new sho ...

Article GUID: 34687682


Body Mass Index Z Score vs Weight-for-Length Z Score in Infancy and Cardiometabolic Outcomes at Age 8-10 Years

Author(s): Roberge JB; Harnois-Leblanc S; McNealis V; van Hulst A; Barnett TA; Kakinami L; Paradis G; Henderson M;

Objectives: To confirm that World Health Organization weight-for-length z scores (zWFL) and World Health Organization body mass index z scores (zBMI) in infancy are associated with adiposity and cardiometabolic measures at 8-10 years old and to compare the predictive ability of the 2 methods. St ...

Article GUID: 34302856


Editorial: Advances in Dietary Fat Absorption

Author(s): Nauli AM; Santosa S; Dixon JB;

No abstract

Article GUID: 34168573


Phase Diagram for a Lysyl-Phosphatidylglycerol Analogue in Biomimetic Mixed Monolayers with Phosphatidylglycerol: Insights into the Tunable Properties of Bacterial Membranes.

Author(s): Wölk C, Youssef H, Guttenberg T, Marbach H, Vizcay-Barrena G, Shen C, Brezesinski G, Harvey RD

Ion pairing between the major phospholipids of the Staphylococcus aureus plasma membrane (phosphatidylglycerol - PG and lysyl-phosphatidylglycerol - LPG) confers resistance to antimicrobial peptides and other antibiotics. We developed 3adLPG, a stable synthetic analogue which can substitute for t ...

Article GUID: 32065707


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