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PARPAL: PARalog Protein Redistribution using Abundance and Localization in Yeast Database

Author(s): Greco BM; Zapata G; Dandage R; Papkov M; Pereira V; Lefebvre F; Bourque G; Parts L; Kuzmin E;

Whole-genome duplication (WGD) events are common across various organisms; however, the retention and evolution of WGD paralogs is not fully understood. Quantitative measure of protein redistribution in response to the deletion of their WGD paralog provides insight into sources of gene retention. ...

Article GUID: 40580499


No species left behind: borrowing strength to map data-deficient species

Author(s): Sharma S; Winner K; Pollock LJ; Thorson JT; Mäkinen J; Merow C; Pedersen EJ; Chefira KF; Portmann JM; Iannarilli F; Beery S; de Lutio R; Jetz W;

We lack the data needed to detect and understand biodiversity change for most species, despite some species having millions of observations. This unequal data coverage impedes conservation planning and our understanding of biodiversity patterns. The 'borrowing strength' approach leverages ...

Article GUID: 40571432


Effect of chronic benzodiazepine and benzodiazepine receptor agonist use on sleep architecture and brain oscillations in older adults with chronic insomnia

Author(s): Barbaux L; Perrault AA; Cross NE; Weiner OM; Es-Sounni M; Pomares FB; Tarelli L; McCarthy M; Maltezos A; Smith D; Gong K; O' Byrne J; Yue V; Desrosiers C; Clerc D; Andriamampionona F; Lussier D; Gilbert S; Tannenbaum C; Gouin JP; Da ...

Study objectives: Insomnia in older adults is associated with widespread benzodiazepine (BZD) and benzodiazepine receptor agonist (BZRA) use, despite evidence that chronic use disrupts sleep regulation and cognition. Little is known about BZD/BZRA effects on NREM slow oscillations (SO), spindles ...

Article GUID: 40570297


Threatened Birds in a Changing Mediterranean Wetland: Long-Term Trends and Climate-Driven Threats

Author(s): Bouregbi I; Bensakhri Z; Zebsa R; Zouaimia A; Bensouilah S; Bouteraa O; Khelifa R; Ouakid ML; Mahdjoub H; Houhamdi M;

Understanding the impact of climate change on waterbirds, particularly those of conservation concern, is essential for their long-term management and effective conservation. In arid regions such as North Africa, wetlands of international importance have been affected by severe drought events, but ...

Article GUID: 40566545


Comprehensive review of reinforcement learning for medical ultrasound imaging

Author(s): Elmekki H; Islam S; Alagha A; Sami H; Spilkin A; Zakeri E; Zanuttini AM; Bentahar J; Kadem L; Xie WF; Pibarot P; Mizouni R; Otrok H; Singh S; Mourad A;

Medical Ultrasound (US) imaging has seen increasing demands over the past years, becoming one of the most preferred imaging modalities in clinical practice due to its affordability, portability, and real-time capabilities. However, it faces several challenges that limit its applicability, such as ...

Article GUID: 40567264


Hearing loss is associated with decreased default-mode network connectivity in individuals with mild cognitive impairment

Author(s): Grant N; Phillips N;

Mild cognitive impairment (MCI) and hearing loss (HL) have been separately associated with increased dementia risk. These highly co-occurring dementia risk factors are associated with aberrant functional brain connectivity. In individuals with HL aberrant functional connectivity has been associated with cognitive impairment. In individuals with MCI, aberr ...

Article GUID: 40567819


Hemodynamic correlates of fluctuations in neuronal excitability: A simultaneous Paired Associative Stimulation (PAS) and functional near infra-red spectroscopy (fNIRS) study

Author(s): Cai Z; Pellegrino G; Spilkin A; Delaire E; Uji M; Abdallah C; Lina JM; Fecteau S; Grova C;

Background: The relationship between task-related hemodynamic activity and brain excitability is poorly understood in humans as it is technically challenging to combine simultaneously non-invasive brain stimulation and neuroimaging modalities. Cortical excitability corresponds to the readiness to ...

Article GUID: 40567300


Unveiling the hidden chronic health risks of nano- and microplastics in single-use plastic water bottles: A review

Author(s): Sajedi S; An C; Chen Z;

Single-use plastic products, such as water bottles, have become ubiquitous in modern society, contributing significantly to the growing problem of plastic waste in landfills, rivers, oceans, and natural habitats. This poses severe threats to biodiversity and ecosystem stability. The emergence of microplastics (1 µm to 5 mm) and nanoplastics (less than 1 µ ...

Article GUID: 40555020


Profiles of Physical Fitness Among Youth with Intellectual Disabilities: A Longitudinal Person-Centered Investigation

Author(s): Maïano C; Morin AJS; Hue O; Tracey D; Craven RG;

Article GUID: 40553251


Printing of Cantilevers and Millifluidic Devices Using Ultrasound Waves

Author(s): Foroughi S; Karamzadeh V; Habibi M; Packirisamy M;

Direct sound printing (DSP) is a recent development in additive manufacturing processes using sound waves, in which cavitation bubbles created by a focused ultrasound field polymerize the liquid resin via the sonochemistry route. This article presents the first attempt to create functional parts, such as cantilevers and millifluidic systems in polydimethy ...

Article GUID: 40538575


Is Adipose Tissue Inflammation the Culprit of Obesity-Associated Comorbidities?

Author(s): Turner L; Wanasinghe AI; Brunori P; Santosa S;

In individuals with obesity, the onset of chronic comorbidities coincides with the excessive accumulation of adipose tissue in various tissue beds. As obesity progresses, adipose tissue becomes increasingly dysfunctional causing chronic low-grade inflammation. Indeed, adipose tissue inflammation, which partially stems from macrophage infiltration and expr ...

Article GUID: 40533358


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