Author(s): Afnan J; Cai Z; Lina JM; Abdallah C; Pellegrino G; Arcara G; Khajehpour H; Frauscher B; Gotman J; Grova C;

Magnetoencephalography (MEG) is widely used for studying resting-state brain connectivity. However, MEG source imaging is ill posed and has limited spatial resolution. This introduces source-leakage issues, making it challenging to interpret MEG-derived connectivity in resting states. To address ...

Article GUID: 40161991

Author(s): Bokhari R; Bisson DG; Fortin M; Vigouroux M; Cata JP; Hwang KP; Chen MM; Ceniza-Bordallo G; Ouellet JA; Ingelmo PM;

Introduction: Pain in lower back is a common condition reported by astronauts, both during and after space missions. Investigating the alterations in the spine and the mechanisms driving these changes is essential for a deeper understanding of how microgravity impacts the human spine. This knowle ...

Article GUID: 40124538

Author(s): Elmekki H; Alagha A; Sami H; Spilkin A; Zanuttini AM; Zakeri E; Bentahar J; Kadem L; Xie WF; Pibarot P; Mizouni R; Otrok H; Singh S; Mourad A;

Cardiac ultrasound (US) scanning is one of the most commonly used techniques in cardiology to diagnose the health of the heart and its proper functioning. During a typical US scan, medical professionals take several images of the heart to be classified based on the cardiac views they contain, wit ...

Article GUID: 40107020

Author(s): Dugré M; Chatelain Y; Glatard T;

Magnetic resonance imaging (MRI) preprocessing is a critical step for neuroimaging analysis. However, the computational cost of MRI preprocessing pipelines is a major bottleneck for large cohort studies and some clinical applications. While high-performance computing and, more recently, deep learning have been adopted to accelerate the computations, these ...

Article GUID: 40072903

Author(s): Rosenstein B; Rye M; Roussac A; Naghdi N; Macedo LG; Elliott J; DeMont R; Weber MH; Pepin V; Dover G; Fortin M;

Study DesignProspective Randomized Controlled Trial.ObjectivesTo investigate the effect of combined motor control and isolated lumbar strengthening exercise (MC + ILEX) vs general exercise (GE) on upper lumbar paraspinal muscle volume and composition, strength and patient outcomes in individuals ...

Article GUID: 40066720

Author(s): Chae Y; Cheers GM; Kim M; Reidler P; Klein A; Fevens T; Holzapfel BM; Mayer-Wagner S;

Cavitary bone defects, defined as a volumetric loss of native bone tissue, require accurate preoperative imaging for treatment planning. While CT (computed tomography) has traditionally been the gold standard for segmentation due to its superior resolution of cortical bone, MRI (magnetic resonance imaging) offers unique advantages, particularly in visuali ...

Article GUID: 40049253

Author(s): Pereira M; Chen X; Paltarzhytskaya A; Pache?o Y; Muller N; Bovy L; Lei X; Chen W; Ren H; Song C; Lewis LD; Dang-Vu TT; Czisch M; Picchioni D; Duyn J; Peigneux P; Tagliazucchi E; Dresler M;

Sleep research has evolved considerably since the first sleep electroencephalography recordings in the 1930s and the discovery of well-distinguishable sleep stages in the 1950s. While electrophysiological recordings have been used to describe the sleeping brain in much detail, since the 1990s neu ...

Article GUID: 39940102

Author(s): Muffels IJJ; Waterham HR; D' Alessandro G; Zagnoli-Vieira G; Sacher M; Lefeber DJ; Van der Vinne C; Roifman CM; Gassen KLI; Rehmann H; Van Haaften-Visser DY; Nieuwenhuis ESS; Jackson SP; Fuchs SA; Wijk F; van Hasselt P;

Background: Deciphering variants of uncertain significance (VUS) represents a major diagnostic challenge, partially due to the lack of easy-to-use and versatile cellular readouts that aid the interpretation of pathogenicity and pathophysiology. To address this challenge, we propose a high-through ...

Article GUID: 39920830

Author(s): Yusefi H; Helfield B;

Clinical ultrasound contrast agent microbubbles remain intravascular and are between 1-8 µm in diameter, with a volume-weighted mean size of 2-3 µm. Despite their worldwide clinical utility as a diagnostic contrast agent, and their continued and ongoing success as a local therapeutic vector, the fundamental interplay between microbubbles - including bubbl ...

Article GUID: 39705920

Author(s): McKay MJ; Weber KA; Wesselink EO; Smith ZA; Abbott R; Anderson DB; Ashton-James CE; Atyeo J; Beach AJ; Burns J; Clarke S; Collins NJ; Coppieters MW; Cornwall J; Crawford RJ; De Martino E; Dunn AG; Eyles JP; Feng HJ; Fortin M; Franettovic ...

Disorders affecting the neurological and musculoskeletal systems represent international health priorities. A significant impediment to progress in trials of new therapies is the absence of responsive, objective, and valid outcome measures sensitive to early disease changes. A key finding in indi ...

Article GUID: 39590726

Author(s): Afnan J; Cai Z; Lina JM; Abdallah C; Delaire E; Avigdor T; Ros V; Hedrich T; von Ellenrieder N; Kobayashi E; Frauscher B; Gotman J; Grova C;

Electro/Magneto-EncephaloGraphy (EEG/MEG) source imaging (EMSI) of epileptic activity from deep generators is often challenging due to the higher sensitivity of EEG/MEG to superficial regions and to the spatial configuration of subcortical structures. We previously demonstrated the ability of the ...

Article GUID: 38994740