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Bioreactor as the root cause of the "manganese effect" during Aspergillus niger citric acid fermentations

Author(s): Fekete E; Bíró V; Márton A; Bakondi-Kovács I; Németh Z; Sándor E; Kovács B; Fábián I; Kubicek CP; Tsang A; Karaffa L;

High-yield citric acid production by the filamentous Ascomycete fungus Aspergillus niger requires a combination of extreme nutritional conditions, of which maintaining a low manganese (II) ion concentration (-1) is a key feature. Technical-scale production of citric acid predominantly uses stainl ...

Article GUID: 35992333


Genetic Screening of Candida albicans Inactivation Mutants Identifies New Genes Involved in Macrophage-Fungal Cell Interactions

Author(s): Godoy P; Darlington PJ; Whiteway M;

Candida albicans, an important fungal pathogen of humans, displays different morphologies, such as yeast, pseudo-hyphae and hyphae, which are recognized unequally by phagocytic cells of the innate immune response. Once C. albicans cells invade host tissues, immune cells such as macrophages are attracted to the site of infection and activated to recognize, ...

Article GUID: 35450285


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