Author(s): Feng Y; Zhen C; Li W; Whiteway M; Fang X; Shen X; Jiang Y; Lu H;

Human body temperature has been shown to limit the antifungal efficacy of azoles; however, the precise mechanisms underlying this limitation remain insufficiently understood. In this study, we observed that short-term exposure (24 h) to human body temperature (37 °C), in contrast to 30 °C, significantly enhances the tolerance of Candida albicans to azoles ...

Article GUID: 42361441

Author(s): Intzandt B; Potvin-Jutras Z; Gauthier CJ;

Circulating sex hormone levels decrease in aging, influencing cerebrovascular health. Estradiol has been shown to support female vascular and brain health, though its effects across the menopausal transition remain unknown. Similarly, the influence of testosterone and other hormones in females is not clear. In males, testosterone is associated with positi ...

Article GUID: 42361914

Author(s): Tikoo S; Noronha AM; Wilds CJ;

In this study, we report the synthesis of an alkylene linker containing a terminal 2-cyanoethyl protected selenium functionality for coupling at the 5'-end of an oligonucleotide by solid phase synthesis for the preparation of oligonucleotide conjugates. Upon deprotection and cleavage from the solid support, quantitative formation of a 5'-diselenid ...

Article GUID: 42322227

Author(s): Perovic M; Phillips NA; Einstein G;

Introduction: Women make up two-thirds of people with Alzheimer's disease (AD). Research has focused on biological explanations for this sex difference, while contributions of psychosocial risk factors are less well understood. Methods: We examined sex differences in the effects of adverse childhood experiences (ACEs) on late-life cognition in groups ...

Article GUID: 42325010

Author(s): Oliviera P; Maye F; Turak A;

Small-molecule π $\pi$ -conjugated semiconductors provide an ordered platform for probing interfacial mechanisms in organic optoelectronics, where device performance and stability are dominated by interface effects. Lithium fluoride, despite its widespread use as an interlayer, remains paradoxical: essential for high device efficiencies yet governe ...

Article GUID: 42316423

Author(s): Wikberg EC; Lucci S; Glotfelty E; Campos F; Sicotte P;

Winners of aggressive intergroup encounters are often assumed to benefit from increased access to resources, but few studies have measured whether there is differential access to resources based on the intergroup outcome. To investigate whether winning intergroup encounters is associated with increased access to food, we used 13 months of data on intergro ...

Article GUID: 42310246

Author(s): Petrossian G; Diouri Y; Xu B; Ebrahimi S; Pande A; Miquet-Westphal F; Xu H; Cicoira F;

Soft, conductive materials that simultaneously offer mechanical compliance, electrical conductivity, recyclability, and scalable manufacturing remain difficult to achieve. Here, we introduce recyclable, 3D-printable PEDOT:PSS syntactic foams based on polymer microspheres coated in situ, enabling precise control over porosity, mechanical properties, and el ...

Article GUID: 42310993

Author(s): Rasoulivalajoozi M; Farhoudi M;

Purpose: Wheelchairs should support not only safe and intuitive navigation but also positive social presence without reinforcing disability-related stereotypes. This study introduces a user-centred external communication framework (ECF) to guide the design of wheelchair external human-machine interfaces and their perceptual dimensions.Materials and method ...

Article GUID: 42300838

Author(s): Nikolic M; Caswell CB; Prada NP; Iqbal M; Cox SML; Jaworska N; Castellanos-Ryan N; Vitaro F; Brendgen M; Parent S; Boivin M; Côté S; Tremblay RE; Séguin JR; Leyton M;

Background: We recently reported evidence that a biopsychosocial model predicts lifetime histories of commonly comorbid early-onset psychiatric disorders. This transdiagnostic model was produced when incorporating either positron emission tomography-measured midbrain dopamine autoreceptors or fun ...

Article GUID: 42293407

Author(s): Wu N; Joyal-Desmarais K; Linkins LA; Flórez ID; Bacon SL;

Background: The COVID-19 pandemic demanded evidence synthesis approaches that could keep pace with rapidly evolving science and urgent policy needs. Rapid reviews and living evidence syntheses (LES) emerged as critical methodological responses, yet limited guidance exists for teams undertaking such work, particularly regarding the operational challenges o ...

Article GUID: 42282099

Author(s): David LeRue

This practitioner reflection examines how painting in plein-air-meaning outdoors from life-inspired multimodal fieldnotes that became the node between research, teaching, and place. This work was conducted during a 4-year, community-engaged art education study where the community art classroom was employed to develop participatory arts-based research meth ...

Article GUID: 42273064