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Contextual variations in the effects of social withdrawal, peer exclusion, and friendship on growth curves of depressed affect in late childhood

Author(s): Commisso M; Persram RP; Lopez LS; Bukowski WM;

The moderating roles of friendship and contextual variables on associations between social withdrawal and peer exclusion and growth curves of depressed affect were studied with a three-wave multilevel longitudinal design. Participants were 313 boys and girls aged 10-12 from Canada (n = 139), mostly of European and North African descent, and Colombia (n = ...

Article GUID: 40583455


PARPAL: PARalog Protein Redistribution using Abundance and Localization in Yeast Database

Author(s): Greco BM; Zapata G; Dandage R; Papkov M; Pereira V; Lefebvre F; Bourque G; Parts L; Kuzmin E;

Whole-genome duplication (WGD) events are common across various organisms; however, the retention and evolution of WGD paralogs is not fully understood. Quantitative measure of protein redistribution in response to the deletion of their WGD paralog provides insight into sources of gene retention. ...

Article GUID: 40580499


No species left behind: borrowing strength to map data-deficient species

Author(s): Sharma S; Winner K; Pollock LJ; Thorson JT; Mäkinen J; Merow C; Pedersen EJ; Chefira KF; Portmann JM; Iannarilli F; Beery S; de Lutio R; Jetz W;

We lack the data needed to detect and understand biodiversity change for most species, despite some species having millions of observations. This unequal data coverage impedes conservation planning and our understanding of biodiversity patterns. The 'borrowing strength' approach leverages ...

Article GUID: 40571432


Multiphase OH Oxidation of Bisphenols: Chemical Transformation and Persistence in the Environment

Author(s): Yu J; Wu B; Peng C; Wentzell J; Wheeler MJ; Osagu JO; Zhang X; Li L; Abbatt JPD; Liggio J;

Bisphenol A (BPA) is a common endocrine disruptor widely found in commercial products. Despite negative human health effects, its usage is not fully banned worldwide with ongoing human exposure from sources including dust, aerosol particles, and surfaces. Although attention has been paid to the a ...

Article GUID: 40569786


Hearing loss is associated with decreased default-mode network connectivity in individuals with mild cognitive impairment

Author(s): Grant N; Phillips N;

Mild cognitive impairment (MCI) and hearing loss (HL) have been separately associated with increased dementia risk. These highly co-occurring dementia risk factors are associated with aberrant functional brain connectivity. In individuals with HL aberrant functional connectivity has been associated with cognitive impairment. In individuals with MCI, aberr ...

Article GUID: 40567819


Protecting shorelines in Canadian Indigenous communities: Environmental challenges, policy interventions, and mitigation technologies

Author(s): Iravani R; Biagi M; Laforest S; Lee K; Isaacman L; Chen Z; An C;

There is growing concern regarding the environmental protection of shorelines in Canadian Indigenous communities, as these regions face increasing threats from pollution and environmental degradation. This review examines various types of pollution affecting coastal Indigenous communities, such as oil spills, plastic waste, industrial runoff, and other co ...

Article GUID: 40554913


Ten new insights in climate science 2024

Author(s): Schaeffer R; Schipper ELF; Ospina D; Mirazo P; Alencar A; Anvari M; Artaxo P; Biresselioglu ME; Blome T; Boeckmann M; Brink E; Broadgate W; Bustamante M; Cai W; Canadell JG; Cardinale R; Chidichimo MP; Ditlevsen P; Eicker U; Feron S; Fik ...

The years 2023 and 2024 were characterized by unprecedented warming across the globe, underscoring the urgency of climate action. Robust science advice for decision makers on subjects as complex as climate change requires deep cross- and interdisciplinary understanding. However, navigating the ev ...

Article GUID: 40546753


Unraveling the resuspension and transformation of stranded oil: Mechanisms driving oil-particle aggregate formation in intertidal zones

Author(s): Yang X; Bi H; Huang G; Zhang H; Lyu L; An C;

The intertidal zone, serving as a dynamic interface, presents a challenging environment for understanding the transport of spilled oil. This study explores the resuspension of stranded oil and the formation of suspended oil-particle aggregates (OPAs) under varying sediment properties, water chemistry, hydrodynamic forces, and biodegradation conditions. Fi ...

Article GUID: 40544777


Is Adipose Tissue Inflammation the Culprit of Obesity-Associated Comorbidities?

Author(s): Turner L; Wanasinghe AI; Brunori P; Santosa S;

In individuals with obesity, the onset of chronic comorbidities coincides with the excessive accumulation of adipose tissue in various tissue beds. As obesity progresses, adipose tissue becomes increasingly dysfunctional causing chronic low-grade inflammation. Indeed, adipose tissue inflammation, which partially stems from macrophage infiltration and expr ...

Article GUID: 40533358


em Candida albicans /em : a historical overview of investigations into an important human pathogen

Author(s): Shrivastava M; Whiteway M;

In recent decades, the study of the opportunistic pathogenic fungus, Candida albicans, has been revolutionized by genomics, transforming our understanding of its molecular biology, pathogenicity, and modes of drug resistance. In this review, our effort is to trace the historical development of C. albicans research, from early clinical observations to mode ...

Article GUID: 40522159


In vitro evaluation of isatin-pyridine oxime hybrids as potential acetylcholinesterase inhibitors for nerve agent prophylaxis

Author(s): Silva MCJD; Pinto AMV; Balthar MA; Correa ABA; Bhattacharyya D; Simas ABC; Kuca K; Forgione P; França TCC; Cavalcante SFA; Kitagawa DAS;

Given the recent deployment of nerve agents as a method of warfare and in targeted assassinations, the development of robust, broad-spectrum medical countermeasures is essential. Our research group has synthesized isatin-pyridine oxime hybrids that have previously demonstrated the ability to resc ...

Article GUID: 40516590


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