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Potential value streams of an integrated Canadian serosurveillance network

Author(s): Campbell JR; Russell WA; Wagner CE; Manuel DG; Anipindi V; Baral P; Evans TG; Hankins CA; Sander B;

The Government of Canada, through the COVID-19 Immunity Task Force (CITF), supported over 100 serosurveillance studies during the COVID-19 pandemic, building and strengthening the technical infrastructure necessary for a national serosurveillance network. The value of such a network extends beyon ...

Article GUID: 40588636


Contextual variations in the effects of social withdrawal, peer exclusion, and friendship on growth curves of depressed affect in late childhood

Author(s): Commisso M; Persram RP; Lopez LS; Bukowski WM;

The moderating roles of friendship and contextual variables on associations between social withdrawal and peer exclusion and growth curves of depressed affect were studied with a three-wave multilevel longitudinal design. Participants were 313 boys and girls aged 10-12 from Canada (n = 139), mostly of European and North African descent, and Colombia (n = ...

Article GUID: 40583455


PARPAL: PARalog Protein Redistribution using Abundance and Localization in Yeast Database

Author(s): Greco BM; Zapata G; Dandage R; Papkov M; Pereira V; Lefebvre F; Bourque G; Parts L; Kuzmin E;

Whole-genome duplication (WGD) events are common across various organisms; however, the retention and evolution of WGD paralogs is not fully understood. Quantitative measure of protein redistribution in response to the deletion of their WGD paralog provides insight into sources of gene retention. ...

Article GUID: 40580499


Single-cell imaging of protein dynamics of paralogs reveals sources of gene retention

Author(s): Dandage R; Papkov M; Greco BM; Pereira V; Fishman D; Friesen H; Wang K; Styles EB; Kraus O; Grys B; Zapata G; Lefebvre F; Bourque G; Boone C; Andrews BJ; Parts L; Kuzmin E;

Gene duplication is common across the Tree of Life and contributes to genomic robustness. In this study, we examined changes in the subcellular localization and abundance of proteins in response to the deletion of their paralogs originating from the whole-genome duplication event, which is a larg ...

Article GUID: 40585364


No species left behind: borrowing strength to map data-deficient species

Author(s): Sharma S; Winner K; Pollock LJ; Thorson JT; Mäkinen J; Merow C; Pedersen EJ; Chefira KF; Portmann JM; Iannarilli F; Beery S; de Lutio R; Jetz W;

We lack the data needed to detect and understand biodiversity change for most species, despite some species having millions of observations. This unequal data coverage impedes conservation planning and our understanding of biodiversity patterns. The 'borrowing strength' approach leverages ...

Article GUID: 40571432


Multiphase OH Oxidation of Bisphenols: Chemical Transformation and Persistence in the Environment

Author(s): Yu J; Wu B; Peng C; Wentzell J; Wheeler MJ; Osagu JO; Zhang X; Li L; Abbatt JPD; Liggio J;

Bisphenol A (BPA) is a common endocrine disruptor widely found in commercial products. Despite negative human health effects, its usage is not fully banned worldwide with ongoing human exposure from sources including dust, aerosol particles, and surfaces. Although attention has been paid to the a ...

Article GUID: 40569786


Effect of chronic benzodiazepine and benzodiazepine receptor agonist use on sleep architecture and brain oscillations in older adults with chronic insomnia

Author(s): Barbaux L; Perrault AA; Cross NE; Weiner OM; Es-Sounni M; Pomares FB; Tarelli L; McCarthy M; Maltezos A; Smith D; Gong K; O' Byrne J; Yue V; Desrosiers C; Clerc D; Andriamampionona F; Lussier D; Gilbert S; Tannenbaum C; Gouin JP; Da ...

Study objectives: Insomnia in older adults is associated with widespread benzodiazepine (BZD) and benzodiazepine receptor agonist (BZRA) use, despite evidence that chronic use disrupts sleep regulation and cognition. Little is known about BZD/BZRA effects on NREM slow oscillations (SO), spindles ...

Article GUID: 40570297


Threatened Birds in a Changing Mediterranean Wetland: Long-Term Trends and Climate-Driven Threats

Author(s): Bouregbi I; Bensakhri Z; Zebsa R; Zouaimia A; Bensouilah S; Bouteraa O; Khelifa R; Ouakid ML; Mahdjoub H; Houhamdi M;

Understanding the impact of climate change on waterbirds, particularly those of conservation concern, is essential for their long-term management and effective conservation. In arid regions such as North Africa, wetlands of international importance have been affected by severe drought events, but ...

Article GUID: 40566545


Comprehensive review of reinforcement learning for medical ultrasound imaging

Author(s): Elmekki H; Islam S; Alagha A; Sami H; Spilkin A; Zakeri E; Zanuttini AM; Bentahar J; Kadem L; Xie WF; Pibarot P; Mizouni R; Otrok H; Singh S; Mourad A;

Medical Ultrasound (US) imaging has seen increasing demands over the past years, becoming one of the most preferred imaging modalities in clinical practice due to its affordability, portability, and real-time capabilities. However, it faces several challenges that limit its applicability, such as ...

Article GUID: 40567264


Hearing loss is associated with decreased default-mode network connectivity in individuals with mild cognitive impairment

Author(s): Grant N; Phillips N;

Mild cognitive impairment (MCI) and hearing loss (HL) have been separately associated with increased dementia risk. These highly co-occurring dementia risk factors are associated with aberrant functional brain connectivity. In individuals with HL aberrant functional connectivity has been associated with cognitive impairment. In individuals with MCI, aberr ...

Article GUID: 40567819


Hemodynamic correlates of fluctuations in neuronal excitability: A simultaneous Paired Associative Stimulation (PAS) and functional near infra-red spectroscopy (fNIRS) study

Author(s): Cai Z; Pellegrino G; Spilkin A; Delaire E; Uji M; Abdallah C; Lina JM; Fecteau S; Grova C;

Background: The relationship between task-related hemodynamic activity and brain excitability is poorly understood in humans as it is technically challenging to combine simultaneously non-invasive brain stimulation and neuroimaging modalities. Cortical excitability corresponds to the readiness to ...

Article GUID: 40567300


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