Author(s): Memari E; Helfield B;
The recent and exciting success of anti-inflammatory therapies for ischemic heart disease (e.g. atherosclerosis) is hindered by the lack of site-specific and targeted therapeutic deposition. Microbubble-mediated focused ultrasound, which uses circulating, l ...
Article GUID: 38988819
Author(s): Gholami Farashah MS; Javadi M; Soleimani Rad J; Shakouri SK; Asnaashari S; Dastmalchi S; Nikzad S; Roshangar L; ...
Purpose: Exosomes are natural nanoparticles that participate in intercellular communication through molecular transport. Recently, due to their membrane vesicular structure and surface proteins, ex ...
Article GUID: 38022800
Author(s): Memari E; Hui F; Yusefi H; Helfield B;
The local fluid dynamics experienced by circulating microbubbles vary across different anatomical sites, which can influence ultrasound-mediated therapeutic delivery efficacy. This study aimed to elucidate the effect of fluid flow rate in combination with r ...
Article GUID: 37150403
Author(s): Choi M; Jazani AM; Oh JK; Noh SM;
Nitric oxide (NO) plays a critical role as an important signaling molecule for a variety of biological functions, particularly inhibiting cell proliferation or killing target pathogens. To deliver active radical NO gaseous molecule whose half-life is a few ...
Article GUID: 35683912
Author(s): Huang HY; Skripka A; Zaroubi L; Findlay BL; Vetrone F; Skinner C; Oh JK; Cuccia LA;
Chronic wounds present a high risk of infection due to delayed and incomplete healing, leading to increased health risks and financial burden to health-care systems. Numerous approaches to promote wound healing have been extensively explored, especially the ...
Article GUID: 35019380
Author(s): Jazani AM; Shetty C; Movasat H; Bawa KK; Oh JK;
Acid-degradable (or acid-cleavable) polymeric nanoassemblies have witnessed significant progress in anti-cancer drug delivery. However, conventional nanoassemblies designed with acid-cleavable linkages at a single location have several challenges, such as, ...
Article GUID: 34050688
Author(s): Copp W, Pontarelli A, Wilds CJ
The chemical and self-assembly properties of nucleic acids make them ideal for the construction of discrete structures and stimuli-responsive devices for a diverse array of applications. Amongst the various three-dimensional assemblies, DNA tetrahedra are o ...
Article GUID: 33506614
Author(s): Huang Y, Jazani AM, Howell EP, Reynolds LA, Oh JK, Moffitt MG
We demonstrate microfluidic manufacturing of glutathione (GSH)-responsive polymer nanoparticles (PNPs) with controlled in vitro pharmacological properties for selective drug delivery. This work leverages previous fundamental work on microfluidic control of ...
Article GUID: 33455300
Author(s): Huang Y, Moini Jazani A, Howell EP, Oh JK, Moffitt MG
Microfluidic flow-directed self-assembly of biological stimuli-responsive block copolymers is demonstrated with dual-location cleavable linkages at the junction between hydrophilic and hydrophobic blocks and on pendant group within the hydrophobic blocks. O ...
Article GUID: 31820915
Author(s): Hyland L, Rosenbaum S, Edwards A, Palacios D, Graham MD, Pfaus JG, Woodside B, Abizaid A
Horm Behav. 2018 01;97:56-66 Authors: Hyland L, Rosenbaum S, Edwards A, Palacios D, Graham MD, Pfaus JG, Woodside B, Abizaid A
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