Author(s): Lacasse JM; Boulos V; Fisher C; Hamilton S; Heron M; Mac Cionnaith CE; Peronace V; Tito N; Brake WG;

During maze navigation rats can rely on hippocampus-mediated place memory or striatum-mediated response memory. Ovarian hormones bias whether females use place or response memory to reach a reward. Here, we investigated the impact of the contraceptive hormones, ethinyl estradiol (EE) and levonorg ...

Article GUID: 36403510

Author(s): Eamonn L Gomez-Perales

Rats can use several memory systems to navigate a maze toward a reward. Two of these are place memory and response memory and female rats can be biased to predominantly use one over another. Both progesterone and estrogens have been shown to alter memory bias. Although the effects of estrogens have been well documented, the effects of progesterone remain ...

Article GUID: 36165431

Author(s): Lacasse JM; Patel S; Bailey A; Peronace V; Brake WG;

17ß-Estradiol (E2) and progesterone (P) influence place and response memory in female rats in spatial navigation tasks. Use of these memory systems is associated with the hippocampus and the dorsal striatum, respectively. Injections of E2 result in a well-established bias to use place memory, while much less is understood about the role of P. A total of 1 ...

Article GUID: 35158200

Author(s): Howland JG; Ito R; Lapish CC; Villaruel FR;

Emerging evidence implicates rodent medial prefrontal cortex (mPFC) in tasks requiring adaptation of behavior to changing information from external and internal sources. However, the computations within mPFC and subsequent outputs that determine behavior are incompletely understood. We review the involvement of mPFC subregions, and their projections to th ...

Article GUID: 35131398