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Transcriptomics identify the triggering of citrate export as the key event caused by manganese deficiency in Aspergillus niger

Author(s): Fekete E; Bíró V; Márton A; Bakondi-Kovács I; Sándor E; Kovács B; Geoffrion N; Tsang A; Kubicek CP; Karaffa L;

For over a century, the filamentous Ascomycete fungus Aspergillus niger has played a pivotal role in the industrial production of citric acid. A critical fermentation parameter that sustains high-yield citric acid accumulation is the suboptimal concentration of manganese(II) ions in the culture b ...

Article GUID: 39377610


Bioreactor as the root cause of the "manganese effect" during Aspergillus niger citric acid fermentations

Author(s): Fekete E; Bíró V; Márton A; Bakondi-Kovács I; Németh Z; Sándor E; Kovács B; Fábián I; Kubicek CP; Tsang A; Karaffa L;

High-yield citric acid production by the filamentous Ascomycete fungus Aspergillus niger requires a combination of extreme nutritional conditions, of which maintaining a low manganese (II) ion concentration (-1) is a key feature. Technical-scale production of citric acid predominantly uses stainl ...

Article GUID: 35992333


Effect of Fe2+ ions on gypsum precipitation during bulk crystallization of reverse osmosis concentrates.

Author(s): Melliti E, Touati K, Van der Bruggen B, Elfil H

In reverse osmosis desalination, the concentrate is a saline solution that may become supersaturated. Heterogeneous nucleation of salts occurs at the membrane surface, resulting in the buildup of inorganic deposits on the membrane. The inorganic nucleation process, however, is complex in natural waters. Most studies focused primarily on single salt foulin ...

Article GUID: 32814139


Biosynthesis of Alkylcitric Acids in Aspergillus niger Involves Both Co-localized and Unlinked Genes.

Author(s): Palys S, Pham TTM, Tsang A

Front Microbiol. 2020;11:1378 Authors: Palys S, Pham TTM, Tsang A

Article GUID: 32695080


The effects of external Mn2+ concentration on hyphal morphology and citric acid production are mediated primarily by the NRAMP-family transporter DmtA in Aspergillus niger.

Author(s): Fejes B, Ouedraogo JP, Fekete E, Sándor E, Flipphi M, Soós Á, Molnár ÁP, Kovács B, Kubicek CP, Tsang A, Karaffa L

Microb Cell Fact. 2020 Jan 30;19(1):17 Authors: Fejes B, Ouedraogo JP, Fekete E, Sándor E, Flipphi M, Soós Á, Molnár ÁP, Kovács B, Kubicek CP, Tsang A, Karaffa L

Article GUID: 32000778


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