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Intrinsic structural covariation links cerebellum subregions to the cerebral cortex

Author(s): Wang Z; Diedrichsen J; Saltoun K; Steele C; Arnold-Anteraper SR; Yeo BTT; Schmahmann JD; Bzdok D;

The human cerebellum is increasingly recognized to be involved in non-motor and higher-order cognitive functions. Yet, its ties with the entire cerebral cortex have not been holistically studied in a whole-brain exploration with a unified analytical framework. Here, we characterized dissociable c ...

Article GUID: 39052236


Mapping pontocerebellar connectivity with diffusion MRI

Author(s): Rousseau PN; Chakravarty MM; Steele CJ;

The cerebellum's involvement in cognitive, affective and motor functions is mediated by connections to different regions of the cerebral cortex. A distinctive feature of cortico-cerebellar loops that has been demonstrated in the animal work is a topographic organization that is preserved across its corticopontine, pontocerebellar, and cerebello-thalmo ...

Article GUID: 36252913


White matter correlates of sensorimotor synchronization in persistent developmental stuttering

Author(s): Jossinger S; Sares A; Zislis A; Sury D; Gracco V; Ben-Shachar M;

Introduction: Individuals with persistent developmental stuttering display deficits in aligning motor actions to external cues (i.e., sensorimotor synchronization). Diffusion imaging studies point to stuttering-associated differences in dorsal, not ventral, white matter pathways, and in the cerebellar peduncles. Here, we studied microstructural white matt ...

Article GUID: 34856426


Early musical training shapes cortico-cerebellar structural covariation

Author(s): Shenker JJ; Steele CJ; Chakravarty MM; Zatorre RJ; Penhune VB;

Adult abilities in complex cognitive domains such as music appear to depend critically on the age at which training or experience begins, and relevant experience has greater long-term effects during periods of peak maturational change. Previous work has shown that early trained musicians (ET; < age 7) out-perform later-trained musicians (LT; > age 7 ...

Article GUID: 34657166


TRAPPC11-related muscular dystrophy with hypoglycosylation of alpha-dystroglycan in skeletal muscle and brain

Author(s): Munot P; McCrea N; Torelli S; Manzur A; Sewry C; Chambers D; Feng L; Ala P; Zaharieva I; Ragge N; Roper H; Marton T; Cox P; Milev MP; Liang WC; Maruyama S; Nishino I; Sacher M; Phadke R; Muntoni F;

Aims: TRAPPC11, a subunit of the transport protein particle (TRAPP) complex is important for complex integrity and anterograde membrane transport from the endoplasmic reticulum (ER) to the ER-Golgi intermediate compartment. Several individuals with TRAPPC11 mutations have been reported with muscl ...

Article GUID: 34648194


Cerebellar Cortex 4-12 Hz Oscillations and Unit Phase Relation in the Awake Rat.

Author(s): Lévesque M; Gao H; Southward C; Langlois JMP; Léna C; Courtemanche R;

Oscillations in the granule cell layer (GCL) of the cerebellar cortex have been related to behavior and could facilitate communication with the cerebral cortex. These local field potential (LFP) oscillations, strong at 4-12 Hz in the rodent cerebellar cortex during awake immobility, should also be an indicator of an underlying influence on the patterns of ...

Article GUID: 33240052


Inhibitory potentials of Cymbopogon citratus oil against aluminium-induced behavioral deficits and neuropathology in rats.

Author(s): Temitayo GI, Olawande B, Emmanuel YO, Timothy AT, Kehinde O, Susan LF, Ezra L, Joseph OO

Cymbopogon citratus is a tropical phytomedicinal plant that is widely known for its hypoglycemic, hypolipidemic, anxiolytic, sedative, antioxidative and anti-inflammatory properties. In this study, we have examined the neuroprotective effects of the essential oil (ESO) of Cymbopogon citratus, following aluminum chloride (AlCl3)-induced neurotoxicity withi ...

Article GUID: 32839358


State-Dependent Entrainment of Prefrontal Cortex Local Field Potential Activity Following Patterned Stimulation of the Cerebellar Vermis.

Author(s): Tremblay SA, Chapman CA, Courtemanche R

Front Syst Neurosci. 2019;13:60 Authors: Tremblay SA, Chapman CA, Courtemanche R

Article GUID: 31736718


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