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The β2-adrenergic biased agonist nebivolol inhibits the development of Th17 and the response of memory Th17 cells in an NF-κB-dependent manner

Author(s): Hajiaghayi M; Gholizadeh F; Han E; Little SR; Rahbari N; Ardila I; Lopez Naranjo C; Tehranimeh K; Shih SCC; Darlington PJ;

Introduction: Adrenergic receptors regulate metabolic, cardiovascular, and immunological functions in response to the sympathetic nervous system. The effect of ß2-adrenergic receptor (AR) as a high expression receptor on different subpopulations of T cells is complex and varies depending on the t ...

Article GUID: 39445009


Weight bias among Canadians: Associations with sociodemographics, BMI and body image constructs

Author(s): Côté M; Forouhar V; Edache IY; Alberga AS;

This cross-sectional study examined the associations between sociodemographic characteristics, BMI, and body image constructs (body satisfaction and weight bias internalization; WBI) and explicit weight bias. A near-representative sample of 995 English-speaking Canadian adults (52% Female) completed a survey which assessed explicit weight bias (Anti-Fat A ...

Article GUID: 38964079


Exploring the association between internalized weight bias and mental health among Canadian adolescents

Author(s): Lucibello KM; Goldfield GS; Alberga AS; Leatherdale ST; Patte KA;

Background: Internalized weight bias (IWB) has been identified as a correlate of higher depressive and anxiety symptoms in adolescents with higher weights. However, there has been limited investigation into how IWB relates to positive mental health and whether these associations differ across genders. Objectives: To examine the associations between IWB a ...

Article GUID: 38676448


Weighty words: exploring terminology about weight among samples of physicians, obesity specialists, and the general public

Author(s): Wilson OWA; Nutter S; Russell-Mayhew S; Ellard JH; Alberga AS; MacInnis CC;

Background: The words used to refer to weight and individuals with large bodies can be used to reinforce weight stigma. Given that most previous research has examined preferred terminology within homogenous groups, this research sought to examine terminology preferences across populations. Methods: This paper reports on data gathered with the general pub ...

Article GUID: 38131299


Putting things right: An experimental investigation of memory biases related to symmetry, ordering and arranging behaviour

Author(s): Radomsky AS; Ouellet-Courtois C; Golden E; Senn JM; Parrish CL;

Background and objectives: Research indicates the presence of both explicit and implicit memory biases for threat. However, empirical support for the presence of memory biases related to symmetry, ordering and arranging is lacking, despite the fact that many individuals report anxiety associated with their personal belongings being out of place. The aim o ...

Article GUID: 37793286


Do trauma cue exposure and/or PTSD symptom severity intensify selective approach bias toward cannabis cues in regular cannabis users with trauma histories?

Author(s): DeGrace S; Romero-Sanchiz P; Tibbo P; Barrett S; Arenella P; Cosman T; Atasoy P; Cousijn J; Wiers R; Keough MT; Yakovenko I; O' Connor R; Wardell J; Rudnick A; Nicholas Carleton R; Heber A; Stewart SH;

Trauma cue-elicited activation of automatic cannabis-related cognitive biases are theorized to contribute to comorbid posttraumatic stress disorder and cannabis use disorder. This phenomenon can be studied experimentally by combining the trauma cue reactivity paradigm (CRP) with cannabis-related ...

Article GUID: 37625353


Weight bias internalization and beliefs about the causes of obesity among the Canadian public

Author(s): Vida Forouhar

CONCLUSIONS: Weight bias internalization is prevalent among Canadians across all body weight statuses, and the public endorses behavioural causes of obesity, namely physical inactivity and overeating, more than its other causes. Findings warrant the reinforcement of efforts aimed at mitigating weight bias by educating the public about the complexity of ob ...

Article GUID: 37620795


Modeling venous bias in resting state functional MRI metrics

Author(s): Huck J; Jäger AT; Schneider U; Grahl S; Fan AP; Tardif C; Villringer A; Bazin PL; Steele CJ; Gauthier CJ;

Resting-state (rs) functional magnetic resonance imaging (fMRI) is used to detect low-frequency fluctuations in the blood oxygen-level dependent (BOLD) signal across brain regions. Correlations between temporal BOLD signal fluctuations are commonly used to infer functional connectivity. However, ...

Article GUID: 37498014


Visual biases in evaluation of speakers' and singers' voice type by cis and trans listeners

Author(s): Marchand Knight J; Sares AG; Deroche MLD;

Introduction: A singer's or speaker's Fach (voice type) should be appraised based on acoustic cues characterizing their voice. Instead, in practice, it is often influenced by the individual's physical appearance. This is especially distressful for transgender people who may be excluded from formal singing because of perceived mismatch between ...

Article GUID: 37205083


Predictors of support for anti-weight discrimination policies among Canadian adults

Author(s): Levy M; Forouhar V; Edache IY; Alberga AS;

Introduction: Weight discrimination of individuals with overweight or obesity is associated with adverse mental and physical health. Weight discrimination is prevalent in many sectors such as within workplaces, where individuals with overweight and obesity are denied the same opportunities as individuals with lower weight status, regardless of performance ...

Article GUID: 37139379


How well do covariates perform when adjusting for sampling bias in online COVID-19 research? Insights from multiverse analyses

Author(s): Joyal-Desmarais K; Stojanovic J; Kennedy EB; Enticott JC; Boucher VG; Vo H; Košir U; Lavoie KL; Bacon SL;

COVID-19 research has relied heavily on convenience-based samples, which-though often necessary-are susceptible to important sampling biases. We begin with a theoretical overview and introduction to the dynamics that underlie sampling bias. We then empirically examine sampling bias in online COVI ...

Article GUID: 36335560


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