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Does Intranasal Oxytocin Reduce Symptoms of Mental Disorders? A Meta-Analysis of Clinical Trials

Author(s): Bonnieux J; Gumuchian ST; Harboun A; Trespalacios F; Bélisle KA; Haddad A; Quintus-Bosz O; McLellan A; Chester-Trudel L; Garred D; Resendes T; Hazel L; Wong SF; Ellenbogen MA;

Intranasal administration of oxytocin has been shown to enhance social cognition and reduce stress reactivity in healthy individuals, suggesting therapeutic potential for mental disorders. However, clinical trials have produced mixed results. Following a systematic search, data were extracted fro ...

Article GUID: 42134427


Sex-specific anxiety and depression multi-trajectories and associated risk factors in the Canadian Partnership for Tomorrow s Health longitudinal study

Author(s): Kapasa RL; Grenon C; Berbiche D; Gouin JP; Vena JE; Vasiliadis HM;

Aims: This study identified sex-specific multi-trajectories of anxiety and depression symptoms among Canadians before and during the COVID-19 pandemic, and associated factors according to a public mental health framework for the surveillance of mental health. Methods: Data from 15,021 participants in the Canadian Partnership for Tomorrow's Health coh ...

Article GUID: 42107659


The effect of a multimodal exercise program on paraspinal muscle morphology and clinical outcomes in chronic low back pain

Author(s): Rosenstein B; Bergevin M; Bobeuf F; Bherer L; Pageaux B; Roy M; Fortin M;

Background: Multimodal exercise programs do not specifically target lumbar paraspinal musculature, but incorporate aspects of different exercises to have an overall benefit. Objective: To investigate the effect of a multimodal exercise program on paraspinal muscle volume and composition, and patient outcomes in individuals with chronic low back pain (CLB ...

Article GUID: 42093855


A Functional Shape Framework for the Detection of Multiple Sclerosis Using Optical Coherence Tomography Images

Author(s): Tahvilian H; Kafieh R; Ashtari F; Swamy MNS; Ahmad MO;

Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease. Optical coherence tomography (OCT) is a non-invasive imaging technique of the retina. The thickness of the ganglion cell-inner plexiform layer (GCIPL) obtained from an OCT image is a valuable biomarker for monitoring MS. Since the functional shape (F-shape)-based technique has prove ...

Article GUID: 42076512


Advanced Separators for Liquid and Quasi-Solid Lithium Rechargeable Batteries: Design and Development

Author(s): Vishweswariah K; Ningappa NG; Kumar M R A; Dawkins JIG; Selva TMG; Zaghib K;

Separators have evolved from passive polymeric barriers into multifunctional components that critically govern the performance, safety, and lifetime of liquid and quasi-solid lithium rechargeable batteries. This Review provides a comprehensive analysis of separator materials and architectures spanning commercial polyolefins and their ceramic coatings, hig ...

Article GUID: 42015518


Quantitative modeling of nanoplastic accumulation from single-use water bottles: exposure scenarios and tissue concentration estimates

Author(s): Sajedi S; An C;

The widespread use of single-use plastic (SUP) water bottles has raised growing concerns about chronic human exposure to nanoplastics (NPs). This study presents a quantitative assessment of NP accumulation in human tissues resulting from the long-term consumption of SUP water bottles. Using survey-derived consumption data and the Human Exposure and Absorp ...

Article GUID: 42007012


Widespread exposure to GLP-1RAs and weight loss-related discourse: Considering potential public health implications

Author(s): Côté M; Ramos Salas X; Carrière K; Alberga AS;

Incretin-based therapies, including glucagon-like peptide-1 receptor agonists (GLP-1RAs), are approved for the treatment of type 2 diabetes, obesity, and related conditions, and have demonstrated significant benefits for individuals with these conditions. However, in recent years, public interest and demand for GLP-1RAs-often driven by media, social media ...

Article GUID: 41986775


Deep learning-based femoral reconstruction from intraoperative point clouds for enhanced knee arthroplasty registration

Author(s): Kafian Safari M; Mirzae M; Gheflati B; Sharifzade M; Zuhars J; Rottoo S; Rivaz H;

Purpose: Computer- and robotic-assisted technologies improve total knee arthroplasty (TKA) through intraoperative bone registration. However, limited bone exposure restricts point collection to the distal femur, omitting key geometric features and reducing registration accuracy and the surgical outcomes. Methods: We introduce a deep learning-based method ...

Article GUID: 41984365


Reliability and Validity of Risk Assessment Tools for Violent Extremism: A Systematic Review

Author(s): Brouillette-Alarie S; Hassan G; Varela W; Danis E; Ousman S; Madriaza P; Pauls IL; Kilinc D; Pickup D; Pelzer R; Borokhovski E;

Assessment of the risk of engaging in a violent radicalization/extremism trajectory has evolved quickly in the last 10 years. Guided by what has been achieved in psychology and criminology, scholars from the field of preventing violent extremism (PVE) have tried to import key lessons from violenc ...

Article GUID: 41978672


Rethinking Obesity Prevention: A Call for Strategic and Operational Clarity

Author(s): Ramos Salas X; Hussey B; Alberga AS; Kyle T; Small F;

Article GUID: 41945228


From periodontitis to neurodegeneration: Can probiotics modulate the em P. gingivalis /em -amyloid pathway in Alzheimer s disease?

Author(s): Sharif-Askari Z; Atoui K; El Zein W; Rizk M; Sharif Askari E;

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the gradual destruction of cognitive and behavioral functions. Despite the continuous research efforts, there is still no cure for this disease. In recent years, researchers have investigated Porphyromonas gingivalis (P. gingivalis) as a potential cause of AD. P. gingivalis-lipo ...

Article GUID: 41940869


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