Author(s): Pontarelli A; Wilds CJ;
The introduction of chemical modifications on the nucleic acid scaffold has allowed for the progress of antisense oligonucleotides (ASOs) in the clinic for the treatment of a variety of disorders. In contribution to the repertoire of gene-silencing nucleic ...
Article GUID: 36857293
Author(s): Liczner C; Duke K; Juneau G; Egli M; Wilds CJ;
Over the past 25 years, the acceleration of achievements in the development of oligonucleotide-based therapeutics has resulted in numerous new drugs making it to the market for the treatment of various diseases. Oligonucleotides with alterations to their sc ...
Article GUID: 33981365
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