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Fitness Costs of Antibiotic Resistance Impede the Evolution of Resistance to Other Antibiotics

Author(s): Chowdhury FR; Findlay BL;

Antibiotic resistance is a major threat to global health, claiming the lives of millions every year. With a nearly dry antibiotic development pipeline, novel strategies are urgently needed to combat resistant pathogens. One emerging strategy is the use of sequential antibiotic therapy, postulated to reduce the rate at which antibiotic resistance evolves. ...

Article GUID: 37726252


A resistome survey across hundreds of freshwater bacterial communities reveals the impacts of veterinary and human antibiotics use

Author(s): Kraemer SA; Barbosa da Costa N; Oliva A; Huot Y; Walsh DA;

Our decreasing ability to fight bacterial infections is a major health concern. It is arising due to the evolution of antimicrobial resistance (AMR) in response to the mis- and overuse of antibiotics in both human and veterinary medicine. Lakes integrate watershed processes and thus may act as receptors and reservoirs of antibiotic resistance genes (ARGs) ...

Article GUID: 36338036


Antibiotic Pollution in the Environment: From Microbial Ecology to Public Policy.

Author(s): Kraemer SA, Ramachandran A, Perron GG

Microorganisms. 2019 Jun 22;7(6): Authors: Kraemer SA, Ramachandran A, Perron GG

Article GUID: 31234491


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