Author(s): Alavi S; Mohammadimoghaddam S; Najmabadi H; Maghsoudlou S;

In this report, we describe a 6-year-old girl with a medical history of pallor, mild icterus, anemia, blood transfusion and abnormal hemoglobin variant analysis on capillary electrophoresis. She was referred for further analysis. DNA sequencing of the proband revealed a de novo mutation in Codon 88 (CTG > CCG) of the ß-globin gene (HBB: c.266T > C) in a h ...

Article GUID: 38500334

Author(s): Heyman HM; Alberts NM; Rees M; Puri L; Frett MJ; Anghelescu DL;

Adolescents with sickle cell disease (SCD) have been shown to have pain-related sequelae following COVID-19 infection. In this case series, we discuss five adolescents with SCD and SARS-CoV-2 infection who subsequently developed complex pain circumstances manifested as: (1) increased frequency of acute care visits or admissions for pain; (2) new onset chr ...

Article GUID: 36467817