Author(s): Won Kang JR; Kim YJ; Skead K; Soave D; Evans J; Bruat V; Harwood MP; Morris Q; Matovu E; Mulindwa J; Noyes H; McLeod A; Hazelhurst S; Lombard Z; Ramsay M; Fave MJ; Awadalla P;

Clonal hematopoiesis, through the age-associated accumulation of somatic mutations in blood, is strongly associated with hematological malignancies and other chronic diseases. These mutations have largely been characterized in individuals of European ancestry or environments, and consequently, it ...

Article GUID: 41282824

Author(s): Lazzari G; Ferreri L; Cattaneo L; Penhune V; Lega C;

The ability to internally generate and maintain a rhythmic pulse, i.e., beat imagery, is a fundamental aspect of musical cognition. While recent theories propose that premotor regions support internal temporal predictions during rhythm perception and imagery, direct causal evidence remains limited. In this study, we investigated the specific contributions ...

Article GUID: 41248776

Author(s): Quirk E; Brouillard M; Ahooja A; Ballinger S; Polka L; Byers-Heinlein K; Kircher R;

Many parents have concerns about raising their children with multiple languages. However, there is a paucity of previous research regarding parental concerns about multilingual child-rearing, particularly in multilingual societies. We address this gap with a corpus-assisted discourse study of parental concerns regarding multilingual child-rearing in Quebe ...

Article GUID: 41199774

Author(s): Ranipa K; Zhu WP; Swamy MNS;

Vision Transformers (ViTs), inspired by their success in natural language processing, have recently gained attention for heart sound classification (HSC). However, most of the existing studies on HSC rely on single-stream architectures, overlooking the advantages of multi-resolution features. While multi-stream architectures employing early or late fusion ...

Article GUID: 41155032

Author(s): Khademi S; Heidarian S; Afshar P; Mohammadi A; Sidiqi A; Nguyen ET; Ganeshan B; Oikonomou A;

In this study, we propose a novel hybrid framework for assessing the invasiveness of an in-house dataset of 114 pathologically proven lung adenocarcinomas presenting as subsolid nodules on Computed Tomography (CT). Nodules were classified into group 1 (G1), which included atypical adenomatous hyp ...

Article GUID: 41150036

Author(s): Paquette V; Danyluk AJ; Gilbert W; Houle SA; Lavoie P; Eltanoukhi R; Morin AJS;

Young adults use a combination of coping strategies to deal with challenges. Yet, limited research has focused on these combinations, as they differ across different profiles of youth and their implications during the major life transitions of emerging adulthood. Addressing this gap, the present longitudinal person-centered study assesses the nature, stab ...

Article GUID: 40924344

Author(s): Zou H; Wang Y; Huang A;

Fine-grained aspect-based sentiment analysis requires language models to identify aspect entities and the corresponding sentiment information in the input text content. Transformer-based pre-trained large language models have demonstrated remarkable performance on various challenging natural language processing tasks. However, large language models face l ...

Article GUID: 40876298

Author(s): Sgro M; Reid ID; Arentshorst M; Ram AFJ; Tsang A;

Many microorganisms are able to use plant-derived aromatic and cyclic compounds like the common plant secondary metabolite quinic acid as carbon and energy sources. In fungi, three enzymatic steps convert quinic acid into the common intermediate protocatechuic acid, which is then further converted into TCA cycle intermediates. The genes encoding these thr ...

Article GUID: 40853219

Author(s): Semper C; Pham TTM; Ram S; Palys S; Evdokias G; Ouedraogo JP; Moisan MC; Geoffrion N; Reid I; Di Falco M; Bailey Z; Tsang A; Benoit-Gelber I; Savchenko A;

Genomics analysis confirmed the status of filamentous fungi as a rich source of novel secondary metabolites; however, the discovery of these compounds is hampered by the cryptic nature of their biosynthetic pathways under laboratory conditions. Consequently, despite substantial research effort ov ...

Article GUID: 40852424

Author(s): Li Z; Chen R; Xing C; Zhong G; Zhang X; Jones KC; Zhu Y;

Organophosphate esters (OPEs) have emerged as a global environmental and health concern due to their persistent, bioaccumulative, and toxic (PBT) properties. Recently, their precursors-organophosphite antioxidants (OPAs)-and transformation products, which may exhibit greater persistence and toxicity, have gained attention as critical contributors to OPE-r ...

Article GUID: 40845576

Author(s): Yu S; Zhang X; Guo T; Li H; Liu W; Chen Z; Wang X; Ren B; Guo J;

Sulfur autotrophic denitrification (SAD) offers a sustainable solution for nitrogen removal in low carbon to nitrogen ratio (C/N) municipal wastewater, yet its efficiency and startup time pose significant challenges. To overcome these, we developed iron-sulfur-modified carriers (FeS@MC) and integrated them into an in-situ sequencing batch reactor (S-Fe-SB ...

Article GUID: 40712941