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A network approach to subjective cognitive decline: Exploring multivariate relationships in neuropsychological test performance across Alzheimer's disease risk states

Author(s): Grunden N; Phillips NA; ;

Subjective cognitive decline (SCD) is characterized by subjective concerns of cognitive change despite test performance within normal range. Although those with SCD are at higher risk for developing further cognitive decline, we still lack methods using objective cognitive measures that reliably distinguish SCD from cognitively normal aging at the group l ...

Article GUID: 38458017


Olfactory function reflects episodic memory performance and atrophy in the medial temporal lobe in individuals at risk for Alzheimer's disease

Author(s): Papadatos Z; Phillips NA;

We examined cognitive domains and brain regions associated with olfactory performance in cognitively unimpaired older adults (CU-OAs) and individuals with or at risk for Alzheimer's Disease (AD). We compared CU-OAs (N = 55), individuals with subjective cognitive decline (SCD, N = 55), mild cognitive impairment (MCI, N = 101), and AD (N = 45) on measur ...

Article GUID: 37146503


Hearing loss is associated with gray matter differences in older adults at risk for and with Alzheimer's disease

Author(s): Giroud N; Pichora-Fuller MK; Mick P; Wittich W; Al-Yawer F; Rehan S; Orange JB; Phillips NA;

Using data from the COMPASS-ND study we investigated associations between hearing loss and hippocampal volume as well as cortical thickness in older adults with subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer's dementia (AD). SCD participants with greater pu ...

Article GUID: 36911511


Financial well-being: Capturing an elusive construct with an optimized measure

Author(s): Aubrey M; Morin AJS; Fernet C; Carbonneau N;

Several definitions and measures of financial well-being (FWB) have been proposed in the scientific literature. The Multidimensional Subjective Financial Well-being Scale (MSFWBS) stands out among these measures in its ability to account for the conceptual richness of FWB. However, the original validation study based on a confirmatory factor analytic mode ...

Article GUID: 36033044


Effects of cognitive behavioral therapy for insomnia on subjective and objective measures of sleep and cognition

Author(s): Perrault AA; Pomares FB; Smith D; Cross NE; Gong K; Maltezos A; McCarthy M; Madigan E; Tarelli L; McGrath JJ; Savard J; Schwartz S; Gouin JP; Dang-Vu TT;

Study objectives: To assess the effects of Cognitive Behavioral Therapy for insomnia (CBTi) on subjective and objective measures of sleep, sleep-state misperception and cognitive performance. Methods: We performed a randomized-controlled trial with a treatment group and a wait-list control group ...

Article GUID: 35691208


Feasibility and preliminary efficacy of the LEAD trial: a cluster randomized controlled lifestyle intervention to improve hippocampal volume in older adults at-risk for dementia

Author(s): N D Koblinsky

CONCLUSIONS: High adherence and retention rates were observed among participants and preliminary findings illustrate improvements in diet quality and HbA1c. These results indicate that a larger trial is feasible if difficulties surrounding recruitment can be mitigated.

Article GUID: 35139918


Visual Performance and Cortical Atrophy in Vision-Related Brain Regions Differ Between Older Adults with (or at Risk for) Alzheimer's Disease

Author(s): Sana Rehan

CONCLUSION: Our findings demonstrate poor visual performance in AD and that both group membership and visual performance are predictors of cortical pathology, consistent with the idea that atrophy in visual areas and pathways contributes to the functional vision deficits observed in AD.

Article GUID: 34397410


Neural correlates of resilience to the effects of hippocampal atrophy on memory.

Author(s): Belleville S, Mellah S, Cloutier S, Dang-Vu TT, Duchesne S, Maltezos S, Phillips N, Hudon C, CIMA-Q group

INTRODUCTION: Cognitive reserve can be defined as a property of the brain that enables an individual to sustain cognitive performance in spite of age-related neural changes. This study uses brain imaging to identify which cognitive reserve mechanisms protect against the detrimental effect of hipp ...

Article GUID: 33360019


Why Are We Together? A Dyadic Longitudinal Investigation of Relationship Motivation, Goal Progress and Adjustment.

Author(s): Holding A, Barlow M, Koestner R, Wrosch C

J Pers. 2019 Aug 16;: Authors: Holding A, Barlow M, Koestner R, Wrosch C

Article GUID: 31420868


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